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Doctor insights on: Invasive Squamous Cell Carcinoma

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Does invasive squamous cell carcinoma spread quickly?

Does invasive squamous cell carcinoma spread quickly?

Depends: Origin of cancer is very important. If skin, usually not unless large, ulcerated lesion. Depending on site, stage at presentation then plays a role. Squamous cancers can origin wherever there is skin lining with then resultant pattern of spread so tough to say more. ...Read more

Dr. Barry Rosen
4,310 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Is invasive squamous cell carcinoma skin cancer more likely to spread than non-invasive?

Surgical excision: That is a pathological description of an excised lesion. There are two major ethos of treating a squamous cell cancers. The first is radiation, but this can leave permanent skin discoloration, and breakdown. Surgical excision with frozen echoing will help rule out. ...Read more

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What is inverted papilloma with dysplasia and foci of in situto invasive squamous cell carcinoma(transitional)?

What is inverted papilloma with dysplasia and foci of in situto invasive squamous cell carcinoma(transitional)?

Location: What is the source of the biopsy? In the paranasal sinuses inverted papilloma is a sinus tumor traditionally treated with surgery, especially if there are foci of carcinoma. ...Read more

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What does this mean? Inverted papilloma with dysplasia and foci of in situ invasive squamous cell carcinoma (transitional)?

What does this mean? Inverted papilloma with dysplasia and foci of in situ invasive squamous cell carcinoma (transitional)?

Premalignant: An inverted papilloma is a tumor in which surface epithelial cells grow downward into the underlying supportive tissue. It may occur in the nose and/or sinuses or in the urinary tract (bladder, renal pelvis, ureter, urethra).. With dysplasia and in-situ squamous Ca this would probably be a premalignant sinus carcinoma bordering on squamous cell Ca needing resection. ...Read more

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What is the prognosis for Stage 2 Invasive squamous cell carcinoma of the lower third of the vagina without conventional treatment. Patient is 65.

What is the prognosis for Stage 2 Invasive squamous cell carcinoma of the lower third of the vagina without conventional treatment. Patient is 65.

Poor prognosis: If left alone or not handled properly the disease will progress thru enlargement and invasion. The anterior vagina is in close proximity to the urethra, its anterior wall shared with bladder and posterior wall with rectum. Radiation with chemo like mitomycin may dramatically shrink if not resolve tumor. If left to grow, the removal procedure is known as pelvic exenteration. ...Read more

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Can invasive moderately differentiated squamous cell carcinoma of esophagus lead to death?

Can invasive moderately differentiated squamous cell carcinoma of esophagus lead to death?

It can: Esophageal cancer is very serious, and is a difficult cancer to treat. For your type, there's debate about the best treatment strategy (surgery vs chemoradiation vs all 3). Your specific prognosis will depend on the stage of disease, but esophagus cancer is always quite serious. Best of luck to you. ...Read more

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Invasive moderately differentiated squamous cell carcinoma.. What does this mean? Severe squamous dysphasia meaning also please.

Invasive moderately differentiated squamous cell carcinoma..
What does this mean? Severe squamous dysphasia meaning also please.

Degree of dysplasia: Squamous cell carcinomas (scc) are categorized in well-, moderately-, and poorly- differentiated tumors based on histological criteria such as keratin production, cohesion of tumor cells, and nuclear and cellular dysplasia. Severe squamous dysplasia means in the context of invading scc that there was also scc-in situ, which is basically scc just before it invaded. ...Read more

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Invasive non keratinizing squamous cell carcinoma tongue showing nests of malignant squamous cells grade 3 prognosis?

Invasive non keratinizing squamous cell carcinoma tongue showing nests of malignant squamous cells grade 3 prognosis?

Can be cured: If no nodes palpable and lesion localized, RT chemo can reduce size and position site for curative resection. Partial glossectomy after initial therapy. If larger and not responsive to chemo, Ive used hight dose MTX with citrovorum factor over 12 hrs. Most effective in presence of nodal disease Basic chemo is Platinum/Taxol + RT ...Read more

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My father has been diagnosed with invasive moderately differentiating keratinising squamous cell carcinoma on his right cheek. Is it curable

My father has been diagnosed with invasive moderately differentiating keratinising squamous cell carcinoma on his right cheek. Is it curable

Likely yes: Provided the tumor is entirely removed, it may be cured. However, patients with sun exposure-related cancers are often susceptible to developing new cancers in sun-exposed skin, so he'll have to be closely followed by a dermatologist going forward, with vigorous use of sunscreen and other sun-protective means (hat, umbrella, etc) during prolonged exposure. ...Read more

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Where can I find squamous cell carcinoma statistics for incidence by age. Looked all over Google and can not locate. ?

Where can I find squamous cell carcinoma statistics for incidence by age.  Looked all over Google and can not locate.
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Won't find them: You already know that everything depends on location, grade, stage, and a few markers depending on the tumor type. Survival curves are age-adjusted. Age has basically no impact on cancer survivability in adults. A squamous skin cancer is very unlikely to kill. A stage IV squamous lung cancer is lethal regardless of age. Hope things go well for you. Best wishes. ...Read more

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How can I tell if squamous cell carcinoma is life threatening?

How can I tell if squamous cell carcinoma is life threatening?

Can be: Squamous cell cancer in advanced untreated forms can be life threatening. It can be locally aggressive by invading critical structures and can also rarely metastasize to distant organs. Some scc like head and neck locations have a high rate of lymph node spread. Purely skin scc is less dangerous overall than melanoma but still requires timely treatment. ...Read more

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What is squamous cell carcinoma like?

What is squamous cell carcinoma like?

Depends on site: Squamous cell carcinomas of the skin are usually slow growing and metastasize only infrequently. Squamous cell carcinomas of the lung are lethal and a majority of the patients are dead within a year. Squamous cell carcinomas of the esophagus, cervix, oro-pharynx etc fall in between. ...Read more

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What is vasive squamous cell carcinoma?

What is vasive squamous cell carcinoma?

"Invasive" - deeper: Skin squamous cell carcinoma (scc) often goes through stages of evolution on its way to becoming "invasive" and eventually metastasizing. It may begin as an area of sun damage or pre-cancer (actinic keratosis) and worsen to become a superficial scc that does not yet invade deeper (scc in situ). Eventually, the scc will start to go deeper and become "invasive", then metastasize if left unchecked. ...Read more

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Can you explain squamous cell carcinoma?

Can you explain squamous cell carcinoma?

SCC: Squamous cells are normal epithelial cells present in a layer of the skin called the epidermis. When the architecture of the cell is distorted, severely disorganized, and has uninhibited growth, it becomes a cancer. ...Read more

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Can children get squamous cell carcinoma?

Can children get squamous cell carcinoma?

Very rarely: Squamous cell carcinomas are uncommon in children. When diagnosed in young individuals, there is usually a predisposing factor like immunosuppression (transplant patients), previous exposure to radiation or chemotherapy, or human papilloma virus infection. Squamous cell cancers of the skin usually takes years of ultraviolet light exposure before appearing at an average age of 65. ...Read more

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What are stages of squamous cell carcinoma?

What are stages of squamous cell carcinoma?

Differentiated: The pathology report will desribe well, moderate or poorly differentiated. Well differentiated is less advanced. It will also describe depth on invasion and whether nerves are involved. An evaluation of lymph nodes is done to confirm squamous cell is localized to skin. In advanced cases it will have spread requiring surgery followed by radiation, and possible chemotherapy. ...Read more

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What does squamous cell carcinoma mean to you?

Subtype of cancer: It only means-a subtype of cancer. Nothing much. The treatment, prognosis etc- will depend on where is this cancer located primarily? , what is the stage ( how big it is? Any lymph node or adjacent tissue involvement? Any spreading to distant organ? Etc. If you smoke tobacco and drink alcohol- you need to quit. Please discuss in detail with your oncologist. ...Read more

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Dr. John Ebner
143 doctors shared insights

Squamous Cell Cancer (Definition)

By definition, these mimic the squamous epithelial surfaces of the body that provide protection. Keratin pearls, prominent desmosomes, apoptosis of individual cells, staining for the distinctive molecules in these surfaces all help ...Read more


Squamous Cell (Definition)

Describes the tile like architecture of cells; however, their behavior is deranged, nuclei irregualrly enlarged and ...Read more