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Doctor insights on: Invasive Squamous Cell Carcinoma

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Does invasive squamous cell carcinoma spread quickly?

Does invasive squamous cell carcinoma spread quickly?

Depends: Origin of cancer is very important. If skin, usually not unless large, ulcerated lesion. Depending on site, stage at presentation then plays a role. Squamous cancers can origin wherever there is skin lining with then resultant pattern of spread so tough to say more. ...Read more

Dr. Barry Rosen
4,214 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Is invasive squamous cell carcinoma skin cancer more likely to spread than non-invasive?

Surgical excision: That is a pathological description of an excised lesion. There are two major ethos of treating a squamous cell cancers. The first is radiation, but this can leave permanent skin discoloration, and breakdown. Surgical excision with frozen echoing will help rule out. ...Read more

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What is inverted papilloma with dysplasia and foci of in situto invasive squamous cell carcinoma(transitional)?

What is inverted papilloma with dysplasia and foci of in situto invasive squamous cell carcinoma(transitional)?

Location: What is the source of the biopsy? In the paranasal sinuses inverted papilloma is a sinus tumor traditionally treated with surgery, especially if there are foci of carcinoma. ...Read more

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What does this mean? Inverted papilloma with dysplasia and foci of in situ invasive squamous cell carcinoma (transitional)?

What does this mean? Inverted papilloma with dysplasia and foci of in situ invasive squamous cell carcinoma (transitional)?

Premalignant: An inverted papilloma is a tumor in which surface epithelial cells grow downward into the underlying supportive tissue. It may occur in the nose and/or sinuses or in the urinary tract (bladder, renal pelvis, ureter, urethra).. With dysplasia and in-situ squamous Ca this would probably be a premalignant sinus carcinoma bordering on squamous cell Ca needing resection. ...Read more

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What is the prognosis for Stage 2 Invasive squamous cell carcinoma of the lower third of the vagina without conventional treatment. Patient is 65.

What is the prognosis for Stage 2 Invasive squamous cell carcinoma of the lower third of the vagina without conventional treatment. Patient is 65.

Poor prognosis: If left alone or not handled properly the disease will progress thru enlargement and invasion. The anterior vagina is in close proximity to the urethra, its anterior wall shared with bladder and posterior wall with rectum. Radiation with chemo like mitomycin may dramatically shrink if not resolve tumor. If left to grow, the removal procedure is known as pelvic exenteration. ...Read more

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Can invasive moderately differentiated squamous cell carcinoma of esophagus lead to death?

Can invasive moderately differentiated squamous cell carcinoma of esophagus lead to death?

Depends: This is not as straight forward a question as it seems. If there is surgical removal of the cancer, no metastatic disease and no involved lymph nodes then there may be a surgical cure. If there is extensive disease other treatment s can sometimes be used such as radiation or chemotherapy in addition to surgery with varying success. ...Read more

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Invasive non keratinizing squamous cell carcinoma tongue showing nests of malignant squamous cells grade 3 prognosis?

Invasive non keratinizing squamous cell carcinoma tongue showing nests of malignant squamous cells grade 3 prognosis?

Can be cured: If no nodes palpable and lesion localized, RT chemo can reduce size and position site for curative resection. Partial glossectomy after initial therapy. If larger and not responsive to chemo, Ive used hight dose MTX with citrovorum factor over 12 hrs. Most effective in presence of nodal disease Basic chemo is Platinum/Taxol + RT ...Read more

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Invasive moderately differentiated squamous cell carcinoma.. What does this mean? Severe squamous dysphasia meaning also please.

Degree of dysplasia: Squamous cell carcinomas (scc) are categorized in well-, moderately-, and poorly- differentiated tumors based on histological criteria such as keratin production, cohesion of tumor cells, and nuclear and cellular dysplasia. Severe squamous dysplasia means in the context of invading scc that there was also scc-in situ, which is basically scc just before it invaded. ...Read more

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My father has been diagnosed with invasive moderately differentiating keratinising squamous cell carcinoma on his right cheek. Is it curable

My father has been diagnosed with invasive moderately differentiating keratinising squamous cell carcinoma on his right cheek. Is it curable

Likely yes: Provided the tumor is entirely removed, it may be cured. However, patients with sun exposure-related cancers are often susceptible to developing new cancers in sun-exposed skin, so he'll have to be closely followed by a dermatologist going forward, with vigorous use of sunscreen and other sun-protective means (hat, umbrella, etc) during prolonged exposure. ...Read more

Dr. John Ebner
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Squamous Cell Cancer (Definition)

By definition, these mimic the squamous epithelial surfaces of the body that provide protection. Keratin pearls, prominent desmosomes, apoptosis of individual cells, staining for the distinctive molecules in these surfaces all help ...Read more


Squamous Cell (Definition)

Describes the tile like architecture of cells; however, their behavior is deranged, nuclei irregualrly enlarged and ...Read more