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Doctor insights on: Invasive Lobular Carcinoma Breast Cancer

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What is the survival rate for a 46 yr old pt with stage 2B invasive lobular breast cancer w/node involvement?

What is the survival rate for a 46 yr old pt with stage 2B invasive lobular breast cancer w/node involvement?

Better than 85%: Invasive lobular carcinoma begins in the milk-producing glands (lobules) of the breast the cells having broken out of the lobule where they began and in Stage IIB have spread to regional lymph nodes. It typically doesn't form a lump, but often causes a fullness in one part of the breast.. They tend to have more hormone-receptor–positive tumors , lower nuclear grade and survival better than 85% ...Read more

Dr. Barry Rosen
1,297 doctors shared insights

Breast Cancer (Definition)

The breast is both a male and female organ. However its main function is in the delivery of milk to the newborn. Breast cancer occurs 95% of the time in women and 5% of the time in men. It is treated the same regardless of which sex it appears in. It comes in two forms invasive and non-invasive; distinction is important as ...Read more


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What is the survival rate for a 46 yr old pt with stage 2B invasive lobular breast cancer w/node involvement?

What is the survival rate for a 46 yr old pt with stage 2B invasive lobular breast cancer w/node involvement?

Approximately 80%: The exact answer to this question depends on a number of factors: actual tumor size, level of estrogen expression, number of nodes involved, medications given and individual response to medications. Lifestyle factors are also key. 80% 5-year survival comes from pooled data from a variety of patients. It's best to ask you medical oncologist to calculate your survival based upon your personal data ...Read more

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My mom had invasive lobular breast cancer. Is that more hereditary than invasive ductal?

My mom had invasive lobular breast cancer. Is that more hereditary than invasive ductal?

Probably no, but...: Most of the statistics I have seen show similar rates of lobular cancer in carriers of BRCA 1/2 mutations (which is the most common recognizable inherited breast cancer trait) compared to non-carriers. Exception: carriers of CDH1 mutations (hereditary diffuse gastric cancer syndrome) have high risk for aggressive stomach cancer and lobular breast cancer. ...Read more

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I have lobular neoplasia. Is it a likely that i will develop breast cancer in the future?

I have lobular neoplasia. Is it a likely that i will develop breast cancer in the future?

Sightly increased...: There is a slightly increased risk of breast cancer with lobular neoplasia, but the majority of women with this diagnosis do not get breast cancer. Some sites describe a 7 to 11 times increased risk for future breast cancer. Tamoxifen may be a consideration for breast cancer prevention. See a breast specialist and consider genetic testing for breast cancer risk analysis. ...Read more

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My mom had lobular breast cancer at 52. Brca negative. Is lobular breast cancer more genetic based than ductal?

My mom had lobular breast cancer at 52. Brca negative. Is lobular breast cancer more genetic based than ductal?

No its medullary: a quote from Lancethttp://www.ncbi.nlm.nih.gov/pubmed/9167459: "The occurrence of invasive lobular carcinoma and invasive ductal carcinoma was not significantly different between carriers of BRCA1 or BRCA2 mutations and controls. Medullary or atypical medullary carcinoma was, however, found more often in BRCA1 (13%, p ...Read more

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My mom was diagnosis with tubulo-lobular breast cancer nottingham score grade 2. Tubule formation was graded 3, with very little tubules . How can this be.?

Mostly lobular: If the tumor is mostly lobular with very little tubule formation it would be graded 3 in terms of tubule formation. The overall grade would still be 2 since the nuclei are usually small sized and the mitotic rate low. These tumors usually have a good prognosis if they are under 2cm and a single focus. ...Read more

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How do doctors know when is chemotherapy needed for ductal and lobular breast cancer?

How do doctors know when is chemotherapy needed for ductal and lobular breast cancer?

Depends: Depends on the stage of the disease, cell type, size of cancer, whether lymph nodes are involved, hormone receptors, dna oncotype testing, etc. Many decades of research helps the medical oncologisr discuss with the patient their options & choices. ...Read more

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My mom had lobular breast cancer at 54 and her paternal cousin had breast cancer at 48. Everyone is brca negative. Is this likely hereditary?

My mom had lobular breast cancer at 54 and her paternal cousin had breast cancer at 48. Everyone is brca negative. Is this likely hereditary?

Hard to tell...: ...without more info. BRCA 1 and 2 are not the only genes known to increase the risk for cancer and there are probably others we do not know anything about. Someone in the family (preferably your mom or her cousin) should visit a genetic counselor (if they have not yet done so) to see what other genes need to be tested if necessary and what else they can do to reduce their risk. ...Read more

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Would the use of skin creams containing phytoestrogens be harmful to me, given that i had oestrogen dependent lobular breast cancer in 2000?

Would the use of skin creams containing phytoestrogens be harmful to me, given that i had oestrogen dependent lobular breast cancer in 2000?

Congrats survivor: Congrats to you for being a 12 year survivor. The risk for developing another breast cancer is back to normal risk (1 in 8). These skin creams can be absorbed depending on how they are prepared and the dosage. I recommend contacting a dermatologist for a recommendation. ...Read more

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Dr. Barry Rosen
4,121 doctors shared insights

Cancer (Definition)

An uncontrolled cell growth leading to invasion and metastases is what cancer is defined as. It produced abnormal growth of cells which acquire destructive properties causing serious threat to host's life, unless it can be removed or destroyed by ...Read more


Dr. Mark Hoepfner
983 doctors shared insights

Breast Carcinoma (Definition)

Breast carcinoma is also known as Breast cancer. Breast carcinoma is a type of cancer where this uncontrolled growth of breast cells. Symptoms can include breast lumps, pain, and weight ...Read more