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Doctor insights on: Intrinsic Factor Blocking Antibody

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Factor viii inhibitor in hemophilia? What is a factor viii inhibitor?

Factor viii inhibitor in hemophilia? What is a factor viii inhibitor?

Antibody to factor: Viii protein. People who are deficient in factor viii, i.e., have severe hemophilia, are treated with infusion of factor viii. Some make antibodies to factor viii and inhibit its function and are called factor viii inhibitors. Rarely non-hemophiliac can also develop such an inhibitor. ...Read more

Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


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Is the Rh factor in blood an antibody or antigen?

Is the Rh factor in blood an antibody or antigen?

Antigen: Rh factor is one the antigens present on red cells. Actually there are a number of subtypes of rh but the one people refer to is rh d antigen. See this site for more info. http://www.ncbi.nlm.nih.gov/books/nbk2269/. ...Read more

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Triple antigen prevents which diseases ?

Triple antigen prevents which diseases ?

Depends: This terminology is used more outside the US and means the combination vaccine against diptheria, tetanus and whooping cough (pertussis), given in a series of scheduled doses, followed by boosters. There is a triple antigen Hepatitis B vaccine (Hepacare) but this is not used in the US. I don't know which countries offer it or even if it is still being offered. ...Read more

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Is rheumatoid facotr different from Rh factor?

Is rheumatoid facotr different from Rh factor?

Rh Factor: Rheumatoid factor is very different from rh, or rhesus factor. Rf represents an autoimmune process, where your body is attacking itself. Rh is the "d" antigen, which makes our blood cells either positive or negative, such as o+ or o-. If it is present on our red blood cells, we do not make antibodies against it, otherwise we would attack our own blood. But if it is neg, then we do make them. ...Read more

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Positive ANA 1:160. Reflex cascade negative. How important is reflex cascade?

Positive ANA 1:160.  Reflex cascade negative.  How important is reflex cascade?

Test: Rheumatologic conditions are truly made by clinical evaluation, as tests often false positives. Hopefully under care of rheumatologist. They have clinical experience to know what's real and what isn't. It takes good clinical history, tests may or may not help, as tests don't make diagnosis, clinical judgement by physician does. What is problem? Lupus?. Confide in physicians clinical judgement not. ...Read more

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Which pain-causing diseases/disorders cause malfunction in transient receptor potential cation channels of subclass a type (trpa1)? Autoantibodies?

Which pain-causing diseases/disorders cause malfunction in transient receptor potential cation channels of subclass a type (trpa1)?  Autoantibodies?

TRPA1 Gene Family: The best article i've read on this gene family is ===> http://www.Genecards.Org/cgi-bin/carddisp.Pl?Gene=trpa1. The clinical significance of mutations in this gene has been related to caffeine and nicotine sensitivity disorders, and rare environmentally-triggered pain disorders. The complete function of this gene family is not known. ...Read more

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What is a recombinant clotting factor product?

What is a recombinant clotting factor product?

Ultra High Tech!: These products(which are used to treat a wide variety of bleeding disorders like hemophilia, and von willebrand's disease) are made either by being completely free of human plasma derivative; or use a pasteurized form that is very safe. These products are not without there share of risks; and can potentially cause diseases as well. They are also very, very expensive so let the buyer beware! ...Read more

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Where Rh factor is present exactly?

Where Rh factor is present exactly?

blood cells: This is a protein, inherited, which is one the surface of red blood cells it is an important component of blood typing and must be matched for donation to prevent reactions. ...Read more

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How are recombinant clotting factor products produced?

How are recombinant clotting factor products produced?

Bacterially, by DNA: Recombinant = dna plasmids are inserted into escherichia coli bacteria to have them make the clotting factor products. ...Read more

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Dr. Liawaty Ho Dr. Ho
3 doctors agreed:
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Is the anti-nmda receptor autoantibody considered a paraneoplastic autoantibody?

Dr. Liawaty Ho Dr. Ho
3 doctors agreed:

Anti NMDA ab: It can be found on anti-nmda receptor encephalitis -which can be related to tumor of the ovaries. Anti nmda can be also found on other conditions such as schizophrenia and narcolepsy associated with psychotic features. Please discuss further with your neurologist and your pmd. ...Read more

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Which nutrient plays an important role in preventing anemia?

Which nutrient plays an important role in preventing anemia?

Mulitple: Anemia can be caused from many things including bleeding (acute or chronic), bone marrow problems, inflammation, or vitamin deficiencies. Vitamin deficiencies associated with anemia include: b12, folate, (folic acid) iron. ...Read more

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Do elevated levels (1300) of IgE play a role in autoimmune diseases?

Do elevated levels (1300) of IgE play a role in autoimmune diseases?

Probably not: High ige is associated with allergy, smoking and some immune deficiency diseases. It is usually not associated with autoimmune diseases. ...Read more

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Blood tests showed high antibodies to: ana, ssdna, sm, rnp/sm, ssa(ro), ssb(la), scl-70, centromere. Is this likely lupus or a different automimmune?

Blood tests showed high  antibodies to: ana, ssdna, sm, rnp/sm, ssa(ro), ssb(la), scl-70, centromere.  Is this likely lupus or a different automimmune?

Prob false positive: To have all these antibodies to be positive is suggestive of a false positive result. Virus infection can cause similiar findings. Ultimately these results have to be interpretted in the context of your doctor's findings. Talk to your doctor. ...Read more

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Which is main causative factor of metabolic syndrome?

Which is main causative factor of metabolic syndrome?

Genetics of torso wt: Insulin resistance is the cause, ie. Your muscles and liver lose sensistivity the bodies own insulin. If you carry weight on the middle and are high waisted you are prone to this, exercise also improves Insulin resistance as well as low carbohydrate diets. ...Read more

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Dr. John Chiu Dr. Chiu
2 doctors agreed:
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Could an immunoglobulin deficiency effectively mask an autoimmune disorder from auto-antibody screens such as AMA ANA etc.or is it a separate thing ?

Dr. John Chiu Dr. Chiu
2 doctors agreed:
Could an immunoglobulin deficiency effectively mask an autoimmune disorder from auto-antibody screens such as AMA ANA etc.or is it a separate thing ?

No: When there is a total deficiency of the immunoglobulin, there can be no autoantibody formed from that particular class of immunoglobulin. Thus it is not a masking. However this does not rule out that other immune mechanisms may not be the cause for a certain illness. ...Read more

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Vit B12 def. Corrected for 5 yrs.Previous +rheumatoid factor, elevated igg, oligoclonal bands, high erythropoietin now large red cells.Possibilities?

Vit B12 def. Corrected for 5 yrs.Previous +rheumatoid factor, elevated igg, oligoclonal bands, high erythropoietin now large red cells.Possibilities?

See your doctor: This problem can only be solved by seeing your doctor and being evaluated face-to-face. After a thorough examination, your doctor should be able to tell you what's wrong and what to do about it. ...Read more

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Simplist terms possible, what Rh factor is?

An antigen: Rh factor is an antigen on the red blood cells which may induce specific antibodies which may destroy the blood cells. ...Read more

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Is factor 7 gene mutation (heterozygote) thrombophila?

Is factor 7 gene mutation (heterozygote) thrombophila?

No: Factor 7 mutation is very rare and causes increased risk of bleeding (not being able to clot). Factor 5 deficiency is the most common form of thrombophilia (increased risk of abnormal clotting). ...Read more