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Doctor insights on: Intravascular Hemolysis

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Doctors, what is the difference between extravascular and intravascular hemolysis?

Doctors, what is the difference between extravascular and intravascular hemolysis?

See below: Intravascular hemolysis refer to breakdown of red cells in the circulating blood. It the more dangerous of the two types. Extravascular hemolysis occurs when red cells are coated with antibody or complement and are taken up macrophages and destroyed outside the circulating blood. Both cause anemia. ...Read more

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Why are intravascular and extravascular hemolysis dangerous?

Why are intravascular and extravascular hemolysis dangerous?

Oxygen carrying RBC: The red blood cells carry oxygen to the tissues of the body. Hemolysis is breakdown or destruction of red blood cells. Without the RBCs, our tissues including heart and brain cannot get enough oxygen. Taken to the extreme, it could be fatal. ...Read more

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What is the classic sign of hemolysis?

What is the classic sign of hemolysis?

Jaundice, dark urine: Commonly jaundice and dark urine can be seen in a patient having hemolysis. Other signs can be subtle such as increasing weakness, fatigue, shortness of breath etc. A hematologist can do the proper blood work to evaluate ongoing hemolysis. ...Read more

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Is it possible for hemolysis to cause hypocalcaemia?

Is it possible for hemolysis to cause hypocalcaemia?

Yes: It can cause it by directly binding calcium, or the subsequent transfusions can lead to hypocalcemia by binding calcium as well. ...Read more

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Is it possible to prevent hemolysis?

Is it possible to prevent hemolysis?

Depends: Are you talking about hemolysis in vivo or in a specimen? There are many caused of hemolysis and each needs a different approach. See this site for info on hemolytic anemia. http://www.ncbi.nlm.nih.gov/pubmedhealth/pmh0001597/. ...Read more

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Why doesn't hemolysis occur when erythrocytes are placed in dextrose?

Why doesn't hemolysis occur when erythrocytes are placed in dextrose?

It's glucose: An isotonic solution of glucose is just a healthy nutrient solution. It's the fuel that red cells use for generating the little bit of energy they need. ...Read more

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How to treat blood hemolysis?

How to treat blood hemolysis?

Please clarify: If you received a lab result of "specimen hemolyzed", then the problem was with the way in which the sample was collected and/or transported to the lab and has no implications for your health beyond making the results less reliable. If you have ongoing hemolysis of you blood cells, you will need to find the cause (many possible) with your physician; perhaps it can be treated. Good luck. ...Read more

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How to treat hemolysis blood?

THere are: Many type of hemolytic anemia. If it is autoimmune and a warm antibody then the first treatment is steroid (prednsione). ...Read more

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How do they test for hemolysis?

How do they test for hemolysis?

Several labs: An elevated reticulocyte count or seeing numerous young red cells on a smear is a tipoff to hemorrhage or hemolysis in a patient. I recommend against haptoglobin or free hemoglobin tests. Coombs test picks up immune sensitization & there are a host of others. There are other situations, such as the blood bank, where other tests work. ...Read more

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