Doctor insights on:
Intrauterine Growth Restriction Connective Tissue Disorder
WHAT DOES BENIGN ENDOMETRIUM WITH A PROLIFERATIVE PATTERN, GLANDULAR BREAKDOWN AND DIFFUSE STROMAL BREAKDOWN - SCANT BENIGN ENDOCERVICAL TISSUE MEAN?
No worries!: Benign is normal or "non-cancerous". Proliferative just means the cells are in the phase where they are dividing which is normal during the estrogen part of the cycle. Endocervical tissue is just cells that came from inside the cervix - these were also benign! All good news! ...Read more
The body is composed of tissue that are classically described as beiing derived from three basic embyonic layers known as the endoderm, mesoderm and ectoderm that then differentiate into the structures that compose the body such as skin, soft tissues, bone, muscle, organs, etc. Stem cells are not differentiated and have the potential to ...Read more
Likley: A combination of both in which genetics predispose you but a trigger or exposure which your body encounters turns on the autoantibodies. ...Read more
Histological section shows mainly decidualised endometrial tissue with hyperplastic glandular component
specimen: uterine evacuation?
Hyperplasia: The sample you describe is suggestive of overgrowth of tissue in the uterus due to irregular menstrual cycles. It is seen in women who go for > 6 months without bleeding and suggests overstimulation due to estrogen effect. If left untreated, it could lead to endometrial cancer. Still, it is very slow growing but needs to be monitored. ...Read more
Connective Tissue : There are over 200 disorders that impact connective tissue. Some, like cellulitis, are the result of an infection. Injuries can cause connective tissue disorders, such as scars. Others, such as ehlers-danlos syndrome, marfan syndrome, and osteogenesis imperfecta, are genetic. Still others, like scleroderma, have no known cause. Each disorder has its own symptoms and needs different treatment. ...Read more
Endometrium is tubular to elongated endometrial glands, separated by dense stroma, and focal crowding of stroma with areas of hemorrhage, nonsecretory?
Abnormal bleeding: The biopsy you described suggests that you are not having regular cycles and your doctor wanted to confirm that there was not a precancerous condition in your uterus. If you go for long periods of time without a menstrual cycle and still have a thick endometrium, it can become precancerous. You may need to take medications to regulate your cycles to prevent these changes. ...Read more
Inactive endometrium with stromal breakdown.
No evidence of hyperplasia or neoplasia. What does this diagnosis?
What type of tissue is the stroma in your iris? A connective tissue , nervous tissue, or epithelial tissue?
Iris: Stroma is made up of fibers & cells. ...Read more
Which connective tissue diseases cause a skin rash? Punch biopsy suggestive of early connective tissue disease.
Is there any known/suspected relationship between. Undifferentiated connective tissue disease and mast cell activation syndrome ?
Unaware: I am not aware of such a connection ...Read more
There are: literally millions of genes that control cell growth not only in pancreatic tissue but throughout the entire body. Why do you ask? ...Read more
Aqua jogging, bike: Exercise limitations associated with mixed connective tissue disorder can be very variable. Some people may be capable of near normal exercise including running, jogging on a treadmill, and planning impact sports. Other people may be much more limited. Good low impact options include aqua jogging, biking (either stationary or regular), swimming, elliptical, and stair climbing. Your choice. ...Read more
Muscular Dystrophies: Muscular dystrophies cause progressive skeletal muscle weakness & wasting. Main types are Duchenne, Becker, limb girdle, congenital, facioscapulohumeral, myotonic, oculopharyngeal, distal, and Emery-Dreifuss, but > 100 similar inherited diseases exist. Most involve an internal organs/systems- heart, endocrine & nervous systems, GI & urinary tracts, skin &/or eyes- at some stage. See mda.org. ...Read more
A real mish-mash...: Causes for any one of the hundreds of connective tissue disorders can vary. Some causes are just simply not known. Injury or trauma can be involved as well as infections. There is also a genetic component to causing some of the disorders. If you suspect a connective tissue problem, consult with your primary care provider for a thorough history and physical evaluation to help identify the cause. ...Read more
Tend to run families: ...But no association I am aware of w/any genetic problems. ...Read more
Depends on how many!: Many diseases are called connective tissue disease, but if you them autimmune diseases, you would include thyroiditis, which causes hypothyroidism. The 10% of the population would have one. But if you define connective disease as rheumatoid arthritis, lupus, mctd, scleroderma, and sjogren's syndrome, then slightly less than 2%. ...Read more
Depends on disease.: In general, many of the connective tissue diseases fall into the realm of a third of patients get worse, a third stay the same and a third get better. An exception to this is RA which usually gets better in pregnancy. Some of the diseases, such as lupus, can increase the risk of miscarriage and blood clot formation during pregnancy. You should consult your OB before conceiving. ...Read moreSee 1 more doctor answer
Please interpret this tissue biopsy. Fibrous pericardium with granulation tissue and fibrinous exudate. There is mild fibroplasia?
Healing: The pericardium has been injured in some way, perhaps by surgery or there may be a healing infection. What is means most of all is there isn't tumor. ...Read more
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