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Doctor insights on: Intrahepatic Cholestasis Of Pregnancy Meconium Stained Amniotic Fluid

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How does meconium stain amniotic fluid causes amniotic fluid embolism?

How does meconium stain amniotic fluid causes amniotic fluid embolism?

It does not!: Meconium passage in utero is common and generally without consequence provided there is no fetal distress. Amniotic fluid embolism is a very rare but almost always lethal maternal complication of late pregnancy. The two conditions are unrelated. ...Read more

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Dr. Jeffrey Wint
4 doctors shared insights

Pregnancy (Definition)

When your due date arrives, you will be more than ready to have your baby! Most women deliver the baby somewhere between 37 and 42 weeks. According to the American College of Obstetricians and Gynecologists, only 5% of babies arrive on the exact due date. Approximately 7% of babies are not delivered by 42 weeks, and when that happens, it is referred to ...Read more


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Can normal seperation of placenta during birth cause Amniotic Fluid Embolisim?

Can normal seperation of placenta during birth cause Amniotic Fluid Embolisim?

Very rare event: Amniotic fluid embolism is a very rare event occurring in about 1/50,000 deliveries. The exact cause in unknown. ...Read more

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Fetal lung fluid & urine make amniotic fluid, right? So what caused oligohydramnios?

Fetal lung fluid & urine make amniotic fluid, right? So what caused oligohydramnios?

Decreased perfusion: Oligo can be either loss of fluid or decreased production. A stressed infant will shunt oxygenated blood to more vital organs, less renal perfusion, therefore less urine produced. Anything that decreases placental perfusion can cause it (abruption or placental separation, poor implantation, vascular problems, clots, uterine abnls, etc). There are too many causes to list here, ask your ob. ...Read more

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If amniotic sac is intact during vaginal delivery or c section, Are chances of AMniotic Fluid Embolisim basically zero chance?

If amniotic sac is intact during vaginal delivery or c section, Are chances of AMniotic Fluid Embolisim basically zero chance?

Yes: Actually, AFE is quite a rare event and, to a degree, independent of a patient's ruptured status. The general idea is that there is a breech and/or permeability of the of the natural blood-amniotic barriers. This allows products of pregnancy to, unaturally, enter the maternal circulation and cause catatrophic events (primarily in the lungs), culminating in death, oftentimes. ...Read more

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Bleeding during first trimester slightly irregular gestational sac 17mm fluid collection beside gestational sac free fluid in cervix baby hr 167?

Bleeding during first trimester slightly irregular gestational sac 17mm fluid collection beside gestational sac free fluid in cervix baby hr 167?

Threaten miscarriage: You need to wait it out and have another ultrasound in a few days. This is a threatened miscarriage. The fht is good. ...Read more

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Is intrahepatic cholestasis of pregnancy painful?

Is intrahepatic cholestasis of pregnancy painful?

NO: Cholestasis of pregnancy does not generally cause pain. The most common symptoms is pruritis (itching). It almost always starts with itching on the palms of the hands and soles of the feet, and it is first noticed at night. The itching spreads to other parts of the body over time. Treatment with ursodiol (bile salts) can improve symptoms. Consultation with a high risk OB is recommended. ...Read more

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Can u leak amniotic fluid at 35 weeks of pregnancy?

Can u leak amniotic fluid at 35 weeks of pregnancy?

Yes, call OB: Call your obstetrician, could be premature rupture of membranes, infection, trauma, other things. ...Read more

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What does dilated fetal kidneys with normal amniotic fluid mean for a second trimester fetus?

What does dilated fetal kidneys with normal amniotic fluid mean for  a second trimester fetus?

No big deal.: Detecting renal problems by fetal ultrasound is very accurate and efficient because it can prevent serious complications postnatally. Fetal renal pyelectasis or even hydronephrosis is nothing to worry about, provided the amniotic fluid is monitored and remains normal. The neonatology team should be notified at birth to institute appropriate follow-up for the newborn; monthly ultrasounds are needed. ...Read more

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Why does c sections increase the risk of amniotic fluid embolism?

Why does c sections increase the risk of amniotic fluid embolism?

2 possibilities: The theoretical reason is that the operative delivery disrupts the tissues and allows amniotic fluid to more easily pass into the woman's blood vessels. But it's not entirely clear if this is a true risk or just an association. Women with suspected amniotic fluid embolism are rushed to c-section. So it's possible it's the other way around, amniotic fluid embolism increases risk of c-section. ...Read more

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How does amniotic fluid dry up in the womb during pregnancy?

How does  amniotic fluid dry up in the womb during pregnancy?

Decreases amniotic : Decreased amniotic fluid level most commonly occurs due to rupture of membranes. Other causes can be due placental insufficiency or fetal renal anomalies. Your baby will continue to normally produce amniotic fluid by voiding. So the amniotic fluid does not dry up. Either less fluid is produced or more fluid is leaving than is produced. ...Read more

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Ultrasound showed fetal demise and collection of fluid after an abortion?

Ultrasound showed fetal demise and collection of fluid after an abortion?

See your doctor: These are symptoms that require a thorough evaluation by your doctor. Only after obtaining this informstion, can he/she adequately diagnose and treat you. ...Read more

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What is the result of liver function tests in intrahepatic cholestasis of pregnancy?

What is the result of liver function tests in intrahepatic cholestasis of pregnancy?

Cholestasis: You could elevated bilirrubin and alkaline phosphatase predominantly. Others sucn as transaminases can be elevated too. They will all normalize upon delivery. ...Read more

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Is 7.5cm amniotic fluid level a sign of concern( 38 week 1 day). What is done in case of low amniotic fluid at this stage of pregnancy?

Is 7.5cm amniotic fluid level a sign of concern( 38 week 1 day). What is done in case of low amniotic fluid at this stage of pregnancy?

> 5: In general we look for an amniotic fluid level above 5 cm at term. 7.5 is normal but it needs to be analyze in terms of your specific pregnancy with your doctor. There may be other issues that change the answer to this question. ...Read more

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What are the risks of disseminated intravascular coagulation after a single fetal demise @ 28 weeks. This a triplet pregnancy - trichorion/triamnio?

What are the risks of disseminated intravascular coagulation after a single fetal demise @  28 weeks.
This a triplet pregnancy - trichorion/triamnio?

I am truly sorry: for a loss of one of your Fetus. At 28 weeks with the advent of Modern medicine and Technology survival rate of other fituses are 100%. All the best ...Read more

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Treatment of fetal demise with colection of fluid in the uterus ?

Treatment of fetal demise with colection of fluid in the uterus ?

Treatment: D&C: You need to see your ob/gyn. He/she needs to verify that the unborn fetus is completely gone. Tissue fragments could lead to infection and pain/bleeding. He may need to do a dilation and currattage. ...Read more

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Eco/level 2 ultrasound revealed thick umbilical cord small amount of fluid around baby's heart. Is this normal? or cause for worry? 1st pregnancy

Eco/level 2 ultrasound revealed thick umbilical cord small amount of fluid around baby's heart.  Is this normal? or cause for worry? 1st pregnancy

Consult G.Y.N.doctor: YourU/S revealing thick umbilical cord and small amount of fluid around baby heart is not normal ,but may be it is going go away (fluid) .Subsequent U/S may show some change in fluid around heart .Persuming there is no other abnormality seen on U/S ,Wish every thing is going to be normal ...Read more

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Male fetus ultrasound (35w 4d) which showed an enlarged fetal bladder. Normal amniotic fluid and kidneys. Is this typical in third trimester?

Male fetus ultrasound (35w 4d) which showed an enlarged fetal bladder. Normal amniotic fluid and kidneys. Is this typical in third trimester?

Specific case: This is a very specific case that requires a doctor to evaluate the exact findings of the sonogram to determine if it is normal or not. You will need to seek clarification from your doctor regarding the term “enlarged bladder” to determine if further testing, follow up sonograms or a referral to a perinatologist is indicated. ...Read more

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Can alzheimer's genes be detected via amniotic fluid before a baby is born?

Can alzheimer's genes be detected via amniotic fluid before a baby is born?

Genes for Alzheimers: Well, the gene for alzheimer's disease isn't known as yet. And their may be more than one cause for what we call alzheimer's disease. So, without knowing what gene causes the disease, we can't detect it by amniocentesis. ...Read more

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Are there things I can do for intrahepatic cholestasis of pregnancy at home?

Are there things I can do for intrahepatic cholestasis of pregnancy at home?

Uncertain: Cause and treatment of intra-hepatic cholestasis are uncertain. Since it is often associated with itching, you need to protect your skin with emollients and refrain from scratching your skin. ...Read more

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How long does pruritus associated with intrahepatic cholestasis of pregnancy last?

Until pregnancy ends: Cholestasis of pregnancy is a considition which generally occurs in the 3rd trimester and is characterized by intense pruritis without rash and increase serum levels of free bile acids. The condition lasts until the pregnancy ends. The pruritis sometimes can be controlled with medications, such as ursodiol. ...Read more

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Which treatment works the best and fastest for intrahepatic cholestasis of pregnancy?

Which treatment works the best and fastest for intrahepatic cholestasis of pregnancy?

See your doc: The one we know it works in relieving the symptoms if itching is the ursodeoxycolic acid. But in pregnancy this is a very serious condition that requires frequent fetal monitoring, maternal monitoring and potentially delivery before your due date. Please see and ob/gyn specialized in high risk pregnancy if you dont have one. ...Read more

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Could I have icp (intrahepatic cholestasis of pregnancy)? What are the risks?

Icp causes itching: I have only had one patient with icp in 27 years of practicing obstetrics. Diagnosis is made by elevated bile salts (detectable by lab test) and the treatment is cholestyramine. Pregnancy outcome should be unaffected by the condition. So icp is rare and makes you miserable, but should not affect your baby. One case however hardly makes me an expert so second opinions welcome. ...Read more

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What is the result of liver function tests in intrahepatic cholestasis of pregnancy?

Cholestasis: You could elevated bilirrubin and alkaline phosphatase predominantly. Others sucn as transaminases can be elevated too. They will all normalize upon delivery. ...Read more

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Is intrahepatic cholestasis of pregnancy painful?

NO: Cholestasis of pregnancy does not generally cause pain. The most common symptoms is pruritis (itching). It almost always starts with itching on the palms of the hands and soles of the feet, and it is first noticed at night. The itching spreads to other parts of the body over time. Treatment with ursodiol (bile salts) can improve symptoms. Consultation with a high risk OB is recommended. ...Read more

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What are the tests for intrahepatic cholestasis of pregnancy?

What are the tests for intrahepatic cholestasis of pregnancy?

LFTs, bile acids.: Liver function tests (alt/ast/alkaline phosphatase) and bile acids can clinch the clinical diagnosis of intrahepatic cholestasis of pregnancy - in the absence of cholelithiasis. ...Read more

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Are some people more prone to getting intrahepatic cholestasis of pregnancy?

Yes: There may be some familial predisposition to this disorder as it seems to apear in clusters of related women. It is also more common with multiple pregnancies (twins/triplets) and recurrence risk is as high as 50% or more in subsequent pregnancies. Resolution of symptoms is usually very prompt after delivery. ...Read more

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How long does abdominal pain associated with intrahepatic cholestasis of pregnancy last?

How long does abdominal pain associated with intrahepatic cholestasis of pregnancy last?

24-48 hrs: Usually all symptoms of intrahepatic cholestasis of pregnancy resolve within 24-48 hrs after delivery, in rare cases sx may continue to up to one week after and may signify retained placenta. But if you have this condition pregnancy needs to be monitored by obgyn very closely as poor outcomes for the baby are not uncommon if not monitored. ...Read more

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I had intrahepatic cholestasis due to alcohol 8 months ago.I didn't drink 6 months.Now i drink.My GGT is 67, indirect bilirubin is1.2 is it ok to drink?

I had intrahepatic cholestasis due to alcohol 8 months ago.I didn't drink 6 months.Now i drink.My GGT is 67, indirect bilirubin is1.2 is it ok to drink?

Probably not: If you have already had liver problems associated with drinking alcohol, it is likely that you are at risk of recurrance and you likely have some permanent liver damage as well. The safest thing that you can do to optimize your health would be to abstain from drinking alcohol at all. I would discuss this with your GI physician. ...Read more

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Can intrahepatic cholestasis be a problem if pregnant?

Can intrahepatic cholestasis be a problem if pregnant?

Cholestasis: Cholestasis in pregnancy can be a serious problem. Usually occurs in the third trimester. It's caused by an excess accumulation of bile acids which can be toxic to the fetus. Leading to fetal distress and can even lead to fetal death. One of the most common symptoms is intense itching. Delivery at 36-37 weeks.
If not term, fetal monitoring and monitor liver enzymes and rx for itching. ...Read more

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What can be done for intraheptic cholestasis of pregnancy?

What can be done for intraheptic cholestasis of pregnancy?

Ursodiol/hydroxyzine: Delivery is the ultimate therapy for cholestasis gravidarum, by 36-38 weeks with 1-2/week fetal surveillance to avoid fetal demise. Oral ursodiol and Hydroxyzine cab help control the bile acid level in the mother's blood stream and decrease her pruritus. ...Read more

Mike Moore Dr. Moore
11 doctors agreed:
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What meds are good for cholestasis of pregnancy?I had it once and don't want to experience it again.

Mike Moore Dr. Moore
11 doctors agreed:

UCDA: Ursodeoxycholic acid (udca) is used in the treatment of intrahepatic cholestasis of pregnancy (icp). We don't know exactly how udca works, but we think it improves bile salt loss from the liver into the bile, which reduces serum bile acid, liver enzyme, and bilirubin levels. This reduces itching, and the risk to the fetus/mother, allowing deliver closer to term. Udca is safe to use in pregnancy. ...Read more

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What are the options of contraception for a woman with liver problems and after cholestasis of pregnancy?

Not hormones: You can use local methods condoms, diaphragm, if u do not want any more kids, office sterilzation, is easier and safer than laparoscopic tubal coagulation. I currently do both adiana and essure in the offcie. If you have a c-section, the tubes can be tied at that time. But as you know tubal methods are permanent, but with your condition, another pregnancy could be risky. ...Read more

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How can YOU DIFFERENTIATE Cholestasis of pregnancy from other itching. Having random spots of itching that feel like prikles on my skin. 28 weeks toda?

How can YOU DIFFERENTIATE Cholestasis of pregnancy from other itching. Having random spots of itching that feel like prikles on my skin. 28 weeks toda?

A few ways: Cholestasis causes total body itching not just in patches or in random areas. Your doctor can do a good test called bile acids. Your doctor can also try you on Ursadiol to see how you respond. Cholestasis will improve. Other causes of itching will not ...Read more

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How far along in pregnancy does cholestasis or pregnancy start? And what is cholestasis of pregnancy?

Cholestasis: Cholestasis of pregnancy is a condition in which the normal flow of bile in the gallbladder is affected by the high amounts of pregnancy hormones. Cholestasis is more common in the last trimester of pregnancy when hormones are at their peak, but it usually goes away within a few days after delivery. ...Read more

Dr. Katherine Kohari
38 doctors shared insights

Cholestasis Of Pregnancy (Definition)

A condition that can occur in pregnancy where the flow of bile, a digestive fluid produced by the liver, slows or stops. As a result, the bile enters the bloodstream and causes intense itching on the palms of the hands and the soles of the feet, plus ...Read more


Dr. Jeffrey Wint
79 doctors shared insights

Cholestasis (Definition)

A condition where the flow of bile, a digestive fluid produced by the liver, slows or stops. As a result, the bile chemicals can get into the bloodstream and cause itching ...Read more