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Doctor insights on: Intrahepatic Cholestasis Of Pregnancy History Of Icp

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Is intrahepatic cholestasis of pregnancy painful?

Is intrahepatic cholestasis of pregnancy painful?

NO: Cholestasis of pregnancy does not generally cause pain. The most common symptoms is pruritis (itching). It almost always starts with itching on the palms of the hands and soles of the feet, and it is first noticed at night. The itching spreads to other parts of the body over time. Treatment with ursodiol (bile salts) can improve symptoms. Consultation with a high risk OB is recommended. ...Read more

Dr. Andrew Berry
4 doctors shared insights

Pregnancy (Definition)

When your due date arrives, you will be more than ready to have your baby! Most women deliver the baby somewhere between 37 and 42 weeks. According to the American College of Obstetricians and Gynecologists, only 5% of babies arrive on the exact due date. Approximately 7% of babies are not delivered by 42 weeks, and when that happens, it is referred to ...Read more


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What is the result of liver function tests in intrahepatic cholestasis of pregnancy?

What is the result of liver function tests in intrahepatic cholestasis of pregnancy?

Cholestasis: You could elevated bilirrubin and alkaline phosphatase predominantly. Others sucn as transaminases can be elevated too. They will all normalize upon delivery. ...Read more

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Could I have icp (intrahepatic cholestasis of pregnancy)? What are the risks?

Icp causes itching: I have only had one patient with icp in 27 years of practicing obstetrics. Diagnosis is made by elevated bile salts (detectable by lab test) and the treatment is cholestyramine. Pregnancy outcome should be unaffected by the condition. So icp is rare and makes you miserable, but should not affect your baby. One case however hardly makes me an expert so second opinions welcome. ...Read more

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What are the tests for intrahepatic cholestasis of pregnancy?

What are the tests for intrahepatic cholestasis of pregnancy?

LFTs, bile acids.: Liver function tests (alt/ast/alkaline phosphatase) and bile acids can clinch the clinical diagnosis of intrahepatic cholestasis of pregnancy - in the absence of cholelithiasis. ...Read more

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What risks are associated with hemangioma of the liver during pregnancy?

What risks are associated with hemangioma of the liver during pregnancy?

Probably none: Unlike hepatic adenomas, the risk of pregnany related increase in size and associated bleeding is minimal to none. ...Read more

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What are the chances of having cholestasis of pregnancy in consecutive pregnancies?

70% recurrance risk: Recurrance risk for cholestasis of pregnancy can be as high as 70% in subsequent pregnancies. There is no current therapy to lessen the risk or prevent those recurrances. ...Read more

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What are the risks of pulmonary hypertension during pregnancy?

What are the risks of pulmonary hypertension during pregnancy?

Big: Very complex condition, if taking era drugs are toxic. Other no, will depend on the pressures, fc, etc.Talk with your ph expert soon or ger a ph center appt. ...Read more

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MRCP "Persistent mild dilation of the central intrahepatic duct. There are areas of mild narrowing & irregularity of the intrahepatic ducts & proximal common duct. No dilation of common bile duct. Gallbladder sludge is present." What causes this?

MRCP "Persistent mild dilation of the central intrahepatic duct. There are areas of mild narrowing & irregularity of the intrahepatic ducts & proximal common duct. No dilation of common bile duct. Gallbladder sludge is present." What causes this?

Nonspecific: I believe that the ductal findings are nonspecific. Sludge in the gall bladder can cause abdominal distress and indigestion. A gastroenterologist would sit down with the radiologist and review the images and decide whether more imaging studies like an MRI or liver biopsy are advisable depending upon your symptoms or lack of symptoms. ...Read more

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What are the early signs of hepatic encephalopothy?

What are the early signs of hepatic encephalopothy?

Confusion: It can vary in how it manifests which can be mild confusion to coma. ...Read more

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What are the effects of gestational diabetes during pregnancy?

What are the effects of gestational diabetes during pregnancy?

Many possible: Diabetes can affect the developing baby throughout the pregnancy. In early pregnancy, a mother's diabetes can result in birth defects and an increased rate of miscarriage. Many of the birth defects that occur affect major organs such as the brain and heart. During the 2nd & 3rd trimester, a mother's diabetes can lead to over-nutrition & excess growth of the baby. ...Read more

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Whats the risk of vomiting during pregnancy?

Whats the risk of vomiting during pregnancy?

Variable: Nausea is very common with vomiting less common during early pregnancy. If vomiting persists to the point weight loss occurs, that can become an issue during pregnancy. The easiest treatment if vitamin b6 and unisom twice daily both available otc. Unisom, of course, can make you drowsy. ...Read more

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Have you noticed any links between the use of isotretinoin and the development of various liver/ biliary system disorders (i.E.: hepatic cholestasis)?

Have you noticed any links between the use of isotretinoin and the development of various liver/ biliary system disorders (i.E.: hepatic cholestasis)?

NO: Isotretinoin is one of the most researched medications on the planet. Roche , the initial company that made the medication, did tons of studies on this med. There have been reported cases of depression, ulcerative colitis, crohn's disease coming on while someone is on isotretinoin. Some of these cases were won in courts of law. Later studies suggested that these were probably coincidence. ...Read more

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Discrete coarsened increased echogenicity of the liver with history of hemochromatosis meaning on ultrasound?

This is : A nonspecific finding on ultrasound though hemochromatosis in one of the many things that can cause this appearance. Magnetic resonance imaging (MRI) is the best imaging examination to evaluate abnormal iron deposition in the liver. ...Read more

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What are the long-term effects of cholestatic jaundice?

What are the long-term effects of cholestatic jaundice?

Several: They depend on cause and age of patient. In preterm infants, it is frequently from prolonged use of TPN and late start of feeds. Majority resolve. In some cases it can cause gall bladder sludge, gall stones or inflammation/infection of the plumbing system of the liver (cholangitis). In extreme cases, these patients can develop cirrhosis and chronic liver failure and may need liver transplant. ...Read more

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Are intermediate FeNO levels an accurate indicator of asthma in the absence of clinical signs?

Are intermediate FeNO levels an accurate indicator of asthma in the absence of clinical signs?

Mgt: FeNO reflects activation of a type of cell associated with allergic lung disease. It can be falsely elevated in some situations. If you have no symptoms, discussing why you had this test with your PCP is advised. If your doctor suspects that you have asthma, I would suggest having a lung function test performed. ...Read more

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What are the risks of pregnancies after peripartum cardiomyopathy?

What are the risks of pregnancies after peripartum cardiomyopathy?

Significant: Even if you fully recover from peripartum cardiomyopathy, the risk of recurrence in subsequent pregnancies can be 20% or more. If you have not fully recovered the risks are much greater. ...Read more

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Could I have icp (intrahepatic cholestasis of pregnancy)? What are the risks?

Icp causes itching: I have only had one patient with icp in 27 years of practicing obstetrics. Diagnosis is made by elevated bile salts (detectable by lab test) and the treatment is cholestyramine. Pregnancy outcome should be unaffected by the condition. So icp is rare and makes you miserable, but should not affect your baby. One case however hardly makes me an expert so second opinions welcome. ...Read more

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Is intrahepatic cholestasis of pregnancy painful?

NO: Cholestasis of pregnancy does not generally cause pain. The most common symptoms is pruritis (itching). It almost always starts with itching on the palms of the hands and soles of the feet, and it is first noticed at night. The itching spreads to other parts of the body over time. Treatment with ursodiol (bile salts) can improve symptoms. Consultation with a high risk OB is recommended. ...Read more

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What are the tests for intrahepatic cholestasis of pregnancy?

LFTs, bile acids.: Liver function tests (alt/ast/alkaline phosphatase) and bile acids can clinch the clinical diagnosis of intrahepatic cholestasis of pregnancy - in the absence of cholelithiasis. ...Read more

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Are some people more prone to getting intrahepatic cholestasis of pregnancy?

Yes: There may be some familial predisposition to this disorder as it seems to apear in clusters of related women. It is also more common with multiple pregnancies (twins/triplets) and recurrence risk is as high as 50% or more in subsequent pregnancies. Resolution of symptoms is usually very prompt after delivery. ...Read more

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Are there things I can do for intrahepatic cholestasis of pregnancy at home?

Are there things I can do for intrahepatic cholestasis of pregnancy at home?

Uncertain: Cause and treatment of intra-hepatic cholestasis are uncertain. Since it is often associated with itching, you need to protect your skin with emollients and refrain from scratching your skin. ...Read more

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Which treatment works the best and fastest for intrahepatic cholestasis of pregnancy?

Which treatment works the best and fastest for intrahepatic cholestasis of pregnancy?

See your doc: The one we know it works in relieving the symptoms if itching is the ursodeoxycolic acid. But in pregnancy this is a very serious condition that requires frequent fetal monitoring, maternal monitoring and potentially delivery before your due date. Please see and ob/gyn specialized in high risk pregnancy if you dont have one. ...Read more

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How long does pruritus associated with intrahepatic cholestasis of pregnancy last?

Until pregnancy ends: Cholestasis of pregnancy is a considition which generally occurs in the 3rd trimester and is characterized by intense pruritis without rash and increase serum levels of free bile acids. The condition lasts until the pregnancy ends. The pruritis sometimes can be controlled with medications, such as ursodiol. ...Read more

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What is the result of liver function tests in intrahepatic cholestasis of pregnancy?

Cholestasis: You could elevated bilirrubin and alkaline phosphatase predominantly. Others sucn as transaminases can be elevated too. They will all normalize upon delivery. ...Read more

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How long does abdominal pain associated with intrahepatic cholestasis of pregnancy last?

How long does abdominal pain associated with intrahepatic cholestasis of pregnancy last?

24-48 hrs: Usually all symptoms of intrahepatic cholestasis of pregnancy resolve within 24-48 hrs after delivery, in rare cases sx may continue to up to one week after and may signify retained placenta. But if you have this condition pregnancy needs to be monitored by obgyn very closely as poor outcomes for the baby are not uncommon if not monitored. ...Read more

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Can intrahepatic cholestasis be a problem if pregnant?

Can intrahepatic cholestasis be a problem if pregnant?

Cholestasis: Cholestasis in pregnancy can be a serious problem. Usually occurs in the third trimester. It's caused by an excess accumulation of bile acids which can be toxic to the fetus. Leading to fetal distress and can even lead to fetal death. One of the most common symptoms is intense itching. Delivery at 36-37 weeks.
If not term, fetal monitoring and monitor liver enzymes and rx for itching. ...Read more

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I had intrahepatic cholestasis due to alcohol 8 months ago.I didn't drink 6 months.Now i drink.My GGT is 67, indirect bilirubin is1.2 is it ok to drink?

I had intrahepatic cholestasis due to alcohol 8 months ago.I didn't drink 6 months.Now i drink.My GGT is 67, indirect bilirubin is1.2 is it ok to drink?

Probably not: If you have already had liver problems associated with drinking alcohol, it is likely that you are at risk of recurrance and you likely have some permanent liver damage as well. The safest thing that you can do to optimize your health would be to abstain from drinking alcohol at all. I would discuss this with your GI physician. ...Read more

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What can be done for intraheptic cholestasis of pregnancy?

What can be done for intraheptic cholestasis of pregnancy?

Ursodiol/hydroxyzine: Delivery is the ultimate therapy for cholestasis gravidarum, by 36-38 weeks with 1-2/week fetal surveillance to avoid fetal demise. Oral ursodiol and Hydroxyzine cab help control the bile acid level in the mother's blood stream and decrease her pruritus. ...Read more

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What are tests, treatment for cholestasis of pregnancy?

What are tests, treatment for cholestasis of pregnancy?

Med, early delivery: Intrahepatic cholestasis is usually first noticed when a pregnant woman complains of itching all over the body but no rash. Testing will show abnormal bile salt levels and liver function tests. There is a medication that relieves the itching and lowers bile salt, but there is increased risk for stillbirth, so close monitoring of the pregnancy and delivery as soon as feasible is usual management. ...Read more

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How long does it take ursodeoxycholic acid to work when you have cholestasis of pregnancy?

How long does it take ursodeoxycholic acid to work when you have cholestasis of pregnancy?

Not long.: Ursodiol can pretty quickly decrease the bile acid levels in cases of intrahepatic cholestasis of pregnancy, however the pruritius may continue until Hydroxyzine is taken. ...Read more

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How far along in pregnancy does cholestasis or pregnancy start? And what is cholestasis of pregnancy?

Cholestasis: Cholestasis of pregnancy is a condition in which the normal flow of bile in the gallbladder is affected by the high amounts of pregnancy hormones. Cholestasis is more common in the last trimester of pregnancy when hormones are at their peak, but it usually goes away within a few days after delivery. ...Read more

Dr. Katherine Kohari
38 doctors shared insights

Cholestasis Of Pregnancy (Definition)

A condition that can occur in pregnancy where the flow of bile, a digestive fluid produced by the liver, slows or stops. As a result, the bile enters the bloodstream and causes intense itching on the palms of the hands and the soles of the feet, plus ...Read more


Dr. Heidi Fowler
79 doctors shared insights

Cholestasis (Definition)

A condition where the flow of bile, a digestive fluid produced by the liver, slows or stops. As a result, the bile chemicals can get into the bloodstream and cause itching ...Read more