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Doctor insights on: Intrahepatic Cholestasis Of Pregnancy History Of Gallstones

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Is intrahepatic cholestasis of pregnancy painful?

Is intrahepatic cholestasis of pregnancy painful?

NO: Cholestasis of pregnancy does not generally cause pain. The most common symptoms is pruritis (itching). It almost always starts with itching on the palms of the hands and soles of the feet, and it is first noticed at night. The itching spreads to other parts of the body over time. Treatment with ursodiol (bile salts) can improve symptoms. Consultation with a high risk OB is recommended. ...Read more

Previous Gallstones (Definition)

Gallstones occur in nearly 25% of women in the U.S. by age 60, and as many as 50% by age 75. In most cases, they have no symptoms. In general, women are probably at increased risk because estrogen stimulates the liver to remove more cholesterol from blood and divert it into the bile. Pregnancy increases the risk for gallstones, and pregnant women with stones are more likely to have symptoms than nonpregnant women. Surgery should be delayed until after delivery if possible. In fact, gallstones may disappear after delivery. If surgery is necessary, laparoscopy ...Read more


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What is the result of liver function tests in intrahepatic cholestasis of pregnancy?

What is the result of liver function tests in intrahepatic cholestasis of pregnancy?

Cholestasis: You could elevated bilirrubin and alkaline phosphatase predominantly. Others sucn as transaminases can be elevated too. They will all normalize upon delivery. ...Read more

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What are the tests for intrahepatic cholestasis of pregnancy?

What are the tests for intrahepatic cholestasis of pregnancy?

LFTs, bile acids.: Liver function tests (alt/ast/alkaline phosphatase) and bile acids can clinch the clinical diagnosis of intrahepatic cholestasis of pregnancy - in the absence of cholelithiasis. ...Read more

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Could I have icp (intrahepatic cholestasis of pregnancy)? What are the risks?

Icp causes itching: I have only had one patient with icp in 27 years of practicing obstetrics. Diagnosis is made by elevated bile salts (detectable by lab test) and the treatment is cholestyramine. Pregnancy outcome should be unaffected by the condition. So icp is rare and makes you miserable, but should not affect your baby. One case however hardly makes me an expert so second opinions welcome. ...Read more

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MRCP "Persistent mild dilation of the central intrahepatic duct. There are areas of mild narrowing & irregularity of the intrahepatic ducts & proximal common duct. No dilation of common bile duct. Gallbladder sludge is present." What causes this?

MRCP "Persistent mild dilation of the central intrahepatic duct. There are areas of mild narrowing & irregularity of the intrahepatic ducts & proximal common duct. No dilation of common bile duct. Gallbladder sludge is present." What causes this?

Nonspecific: I believe that the ductal findings are nonspecific. Sludge in the gall bladder can cause abdominal distress and indigestion. A gastroenterologist would sit down with the radiologist and review the images and decide whether more imaging studies like an MRI or liver biopsy are advisable depending upon your symptoms or lack of symptoms. ...Read more

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What risks are associated with hemangioma of the liver during pregnancy?

What risks are associated with hemangioma of the liver during pregnancy?

Probably none: Unlike hepatic adenomas, the risk of pregnany related increase in size and associated bleeding is minimal to none. ...Read more

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What are the symptoms of biliary cirrhosis?

What are the symptoms of biliary cirrhosis?

Jaundice & itching: Primary biliary cirrhosis is an autoimmune phenomenon and may be associated with damage to other organs. The prominent symptoms of biliary cirrhosis are jaundice and itching. With progression symptoms of liver failure, e.g., edema, bleeding, ascites etc appear. ...Read more

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What are the chances of having cholestasis of pregnancy in consecutive pregnancies?

70% recurrance risk: Recurrance risk for cholestasis of pregnancy can be as high as 70% in subsequent pregnancies. There is no current therapy to lessen the risk or prevent those recurrances. ...Read more

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I have all symptoms of gall/b cancer. Jaundice, vometing,full of gallstones. G/stones being removed in 3 weeks.Is there any test to diagnose gall/b Cancer before surgery?

I have all symptoms of gall/b cancer. Jaundice, vometing,full of gallstones. G/stones being removed in 3 weeks.Is there any test to diagnose gall/b Cancer before surgery?

Low probability : you have a very low chance of cancer. The stones explain the symptoms. The symptoms are more of an obstructed biliary tree. Stones have clogged up your bile duct. Was any imaging done? I am presuming you may have had a ultrasound or ct scan. Hopefully they can help you sooner than 3 weeks. The imaging should pick up any mass in the gall bladder. Your risk is low. Best of luck ...Read more

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What are the complications of pancreatic cysts, pseudocysts?

What are the complications of pancreatic cysts, pseudocysts?

Infection: It could get infected, bleeding, fistula. www.drlugo.com. ...Read more

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What is acute fatty liver of pregnancy?

Fatty liver: Acute fatty liver of pregnancy (aflp) is a rare, potentially fatal complication that occurs in the third trimester or early postpartum period. Although the exact pathogenesis is unknown, this disease has been linked to an abnormality in fetal fatty acid metabolism. Early diagnosis of aflp sometimes can be difficult because it shares features with other common conditions such as pre-eclampsia, vira. ...Read more

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Ultrasound results: large gallstone present in neck of gallbladder and tumefactive sludge. What is meaning?

Ultrasound results: large gallstone present in neck of gallbladder and tumefactive sludge. What is meaning?

See below: It means a gallstone is stuck in the neck of the gallbladder and preventing biles from leaving the gallbladder, causing the biles to clump up into debris, instead of being bile fluid. I would recommend talking to your physician regarding appropriate management. ...Read more

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What are the causes of a fatty liver of pregnancy?

What are the causes of a fatty liver of pregnancy?

Enzyme deficiency: The association of cases of acute fatty liver of pregnancy with one of the inherited defects in mitochondrial beta-oxidation of fatty acids (the acronym for which is lchad), suggests that some affected women and their fetuses might have an inherited enzyme deficiency in beta-oxidation that predisposes the mother to this disorder. ...Read more

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Which one increase risk of gallbladder cancer: acalculus cholecystitis(no stone) or fistula in gallbladder and intestine? ?

Which one increase risk of gallbladder cancer: acalculus cholecystitis(no stone) or fistula in gallbladder and intestine? ?

Both conditions: By themselves probably do not increase chance of gallbladder cancer. If it does, it is still very very low. Even if you have gallstones, chances of developing gallbladder cancer is very low. Unfortunately, once you develop gallbladder cancer, chances of survival are quite low. ...Read more

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What are the symptoms of liver disease iin pregnancy?

Depends: There are some liver diseases that are related to pregnancy (common). On the other hand, someone may have pre-existing liver disease. Symptoms of pregnancy related liver disease vary from no symptom (only blood work will show abnormal liver tests) to itching, nausea/vomiting, belly pain, leg swelling, high blood pressure and signs of liver failure etc. ...Read more

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What are early signs & symptoms of primary biliary cirrhosis?

None: Early on primary biliary cirrhosis can be associated with little or no symptoms at all, just like many chronic liver diseases. As the disease progresses, however, many people start experiencing chronic fatigue & weakness, jaundice and itching (from bilirubin build up in skin), followed by complications of cirrhosis such as ascites & malnutrition. ...Read more

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Describe the features of biliary cirrhosis.?

Describe the features of biliary cirrhosis.?

Liver failure: There are many things that happen with cirrhosis, depending on how severe it is. These include confusion, bleeding from the GI tract, jaundice, fluid buildup in the belly, increased risk for liver cancer, and other symptoms. ...Read more

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Dr. Dariush Saghafi
4 doctors shared insights

Pregnancy (Definition)

When your due date arrives, you will be more than ready to have your baby! Most women deliver the baby somewhere between 37 and 42 weeks. According to the American College of Obstetricians and Gynecologists, only 5% of babies arrive on the exact due date. Approximately 7% of babies are not delivered by 42 weeks, and when that happens, it is referred to ...Read more


Dr. Katherine Kohari
38 doctors shared insights

Cholestasis Of Pregnancy (Definition)

A condition that can occur in pregnancy where the flow of bile, a digestive fluid produced by the liver, slows or stops. As a result, the bile enters the bloodstream and causes intense itching on the palms of the hands and the soles of the feet, plus ...Read more