Doctor insights on:
Intra Ductal Papilloma
Viral insertion: DCIS is the earliest phase of transformation to malignancy developing in the ductal system before invasion into parenchyma has occurred. It is defined on mammo by clustered microcalcification. In general the long terminal repeat of the MMTV viral genome enters the ductal cell to initiate transformation. with time the cells become aggressive and invade basement membrane helped by the EBV virus ...Read more
Breastduct excision fibrocystic changes,ductal hyperplasia w/o atypical,apocrine metaplasia,dilated benign ducts with thermal artifact.this means what?
No cancer: All of the changes in your breast are benign and there is no cancer. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more
Send us UR? in Engli: Sorry I can not read Spanish. But if you have Invasive ductal carcinoma...that means cancer. If it is not invasive(it is called Ductal carcinoma in situ) that is a pre-cancer. Go see a surgeon and ask for advice for further treatment as you will likely need surgery to remove either one of the two conditions that I have mentioned. ...Read more
Many organs: The first likely tissue where metastases occurs in invasive ductal cancer is the lymph nodes on the armpit or behind the chest wall. Other organs may include the bones, lungs, liver, brain, adrenal glands, skin, bone marrow, the lining around the lungs or heart or the abdomen. Other parts of the body are less often sites of spread. ...Read more
Stage-Dependent: Breast cancers are staged based upon the size of the cancer, lymph node or distant organ involvement, and unique molecular features of the tumor. Published rates of 5-yr survival (http://www.Cancer.Org/cancer/breastcancer/detailedguide/breast-cancer-survival-by-stage) vary quite a bit based on these variables, between 15%-93%. The type of cancer (ductal, lobular, etc) doesn't impact survival. ...Read more
No: Although both are breast cancers they are different in the significance attached to them. Lobular carcinoma is more likely to be larger, lymph node positive and estrogen positive then invasive ductal. A study in the ann surg oncol. 2010 jul;17(7):1862-9. Epub 2010 feb 17 suggests that invasive lobular carcinoma has a better prognosis stage for stage than invasive ductal carcinoma. ...Read more
What does this mean? Inverted papilloma with dysplasia and foci of in situ invasive squamous cell carcinoma (transitional)?
Premalignant: An inverted papilloma is a tumor in which surface epithelial cells grow downward into the underlying supportive tissue. It may occur in the nose and/or sinuses or in the urinary tract (bladder, renal pelvis, ureter, urethra).. With dysplasia and in-situ squamous Ca this would probably be a premalignant sinus carcinoma bordering on squamous cell Ca needing resection. ...Read more
Grade 2 invasive ductal carcinoma infiltrating as cords and tumour cells in a fibroadipose stroma, what does this mean?
Grade 2: There are 2 basic forms of breast cancer, ductal and lobular. Yours tumor is a ductal but it sounds like it has some lobular features, in particular it's infiltrating as cords sometimes called "Indian file infiltration". I don't think this has any clinical significance. See your oncologist and follow their advice. Most important is knowing lymph node status. Best of luck and God bless. ...Read moreSee 1 more doctor answer
Bilateral lung nodules,Atelectasis prior papilloma thyroid CA.Pituitary Adenoma,Chiari Malformation,FMD,enlarged common bile duct no stones. Genetic?
Maybe genetic: Probably should have genetic consult. Forinstance Chiari malformation, fibromuscular dysplasia, and thyroid cancer can be associated with neurofibromatosis. Lung nodules are non specific and can be from some infections but also metastatic disease sometimes from papillary thyroid cancer. You may want to consult a geneticist physician. ...Read more
Invasive non keratinizing squamous cell carcinoma tongue showing nests of malignant squamous cells grade 3 prognosis?
Can be cured: If no nodes palpable and lesion localized, RT chemo can reduce size and position site for curative resection. Partial glossectomy after initial therapy. If larger and not responsive to chemo, Ive used hight dose MTX with citrovorum factor over 12 hrs. Most effective in presence of nodal disease Basic chemo is Platinum/Taxol + RT ...Read more
Maybe, maybe not: If the tumor is benign then it might not need to come out. However, if it's in there long enough, it might start to cause problems like blocking the ducts to your mammary glands. Also, just because it's benign today doesn't mean it won't transform at some point. It might be worth having it out, if it's simple and easy to do. See your local surgeon for more ideas. ...Read moreSee 1 more doctor answer