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Doctor insights on: Interpreting Acth Stimulation Test

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Acth stimulation test results accurate?

Acth stimulation test results accurate?

Depends: I'm assuming no lab errors. If you get a very high cortisol spike after receiving the first dose of ACTH, you are reassured you do not have Addison's. No, or a very small spike, strongly suggests Addison's. In-between... that's why there are specialist endocrinologists.

Acth Stimulation Test (Definition)

The acth stimulation test evaluate whether the adrenal gland can respond to stimulation from the pituitary gland by giving an artificial form of the pituitary hormone (acth) and measuring the adrenal gland hormone (cortisol) before and after the injection. Normally the cortisol level will rise after the injection; in most instances failure to do so indicates a problem ...Read more


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What is the definition or description of: acth stimulation test?

What is the definition or description of: acth stimulation test?

Eval adrenal functio: The acth stimulation test evaluate whether the adrenal gland can respond to stimulation from the pituitary gland by giving an artificial form of the pituitary hormone (acth) and measuring the adrenal gland hormone (cortisol) before and after the injection. Normally the cortisol level will rise after the injection; in most instances failure to do so indicates a problem with the adrenal gland.

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Regarding acth stimulation test. Do I have to be experiencing symptoms at time of test in order for it to show positive result?

Regarding acth stimulation test. Do I have to be experiencing symptoms at time of test in order for it to show positive result?

No symptoms needed: The test is designed to test the ability of your adrenal glands to respond to stimulation from the pituitary (by giving a synthetic form of the pituitary hormone), so it is not necessary to have symptoms for the test to be valid. The ability of the adrenal gland to respond to stimulation does not come and go on a short term basis, so the results will be the same no matter how one feels.

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Can I drive myself after acth stimulation test or should I have someone drive me? I don't know what to expect? Might I feel better or worse after?

Can I drive myself after acth stimulation test or should I have someone drive me? I don't know what to expect? Might I feel better or worse after?

Yes: An acth stim test. A cortisol blood test, an injection of cortrisyn followe by another cortisol blood test. It takes time, but you should be able to drive to and from work. Best wishes.

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ACTH Stimulation Test results: baseline cortisol 6.2, 30 min 19.4, 1 hour 22.7. Suspect SAI?

ACTH Stimulation Test results: baseline cortisol 6.2, 30 min 19.4, 1 hour 22.7. Suspect SAI?

While there can be: Variation between labs, these results appear to be largely normal. The baseline is normal (5-23 micrograms per deciliter). A rise from baseline of at least 7 to 10 ug/dl of cortisol, reaching at least 18 ug/dl at 60 minutes post-stimulation rules out primary adrenal insufficiency. A blunted response (not sure yours qualifies) may suggest secondary AI. Your Doctor will advise you. Stay well.

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What is the difference between acth plasma and acth stimulation test? Which one is more reliable and accurate? Can you depend solely on acth plasma?

What is the difference between acth plasma and acth stimulation test? Which one is more reliable and accurate? Can you depend solely on acth plasma?

Plasma: Is the amount of acth in your blood "free hormone" level. The acth stimulation test is used to determine if the adrenal glands are functioning properly. Depending on your symptoms, one or both test are needed. Speak with your physician for rutherford dealers.

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What is an acth stimulation test for?

What is an acth stimulation test for?

Adrenal test: It's a test to see if you have adrenal insufficiency (whether or not your adrenals are working). It typically requires a placement of an iv, blood draws from the IV line as well as injection of acth through the iv. It can be done in a doctor's office or in an infusion center.

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Acth stimulation test -- is that done in a lab?

Acth stimulation test -- is that done in a lab?

Yes and no.: Provocative acth is given iv. Serial blood measurements are made for detecting the rise in cortisol in the blood. These assays are done in a lab.

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I've been showing strong symptoms of addisons disease. Should I opt for an acth stimulation test?

Yes if indicated: If you have symptoms of adrenal insufficiency, talk to your doctor about the acth stim test. This is the best test to confirm your suspicion. If he/she agrees with your assessment, the test should be ordered. Good luck.

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What is the indication and contraindication of acth stimulation test? What is the management for acth stimulation test?

What is the indication and contraindication of acth stimulation test? What is the management for acth stimulation test?

See below: Acth stimulation allows a doctor to distinguish primary adrenal disease from pituitary disease. This is not an issue for self testing or management. See this site for more information and discuss the matter with your doctor. Http://www. Nlm. Nih. Gov/medlineplus/ency/article/003696.htm.

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Is acth stimulation test done at a normal lab that draws blood?

Is acth stimulation test done at a normal lab that draws blood?

ACTH test: The lab can draw blood for measurement of cortisol, but someone has to give the injection of acth (cortrosyn). The injection can be given IV or im. A lab that only draws blood would probably not be able to do this. Someone needs to order the acth and give the injection.

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Acth Stimulation test: PRG 17-0H basal: 3.70nmol/l 30min interval: 9.83nmol/l 60min interval: 12nmol/l Heterozygous or Homozygous NCAH? Or Pcos?

Acth Stimulation test: PRG 17-0H basal: 3.70nmol/l 30min interval: 9.83nmol/l 60min interval: 12nmol/l Heterozygous or Homozygous NCAH? Or Pcos?

NCAH or PCOS?: Not nonclassic adrenal hyperplasia with early morning 17-OH progesterone less than 200ng/dl. Yours, with conversion is 122ng/dl. Also, your stimulated level doesn't reach higher than 400ng/L. That means no 21-hydroxylase or 11beta-hydroxylase or 3-beta-hydroxysteroid dehydrogenase or 17-alpha-hydroxylase deficiency. PCOS.

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Can prednisone affect an acth stimulation test? I'm on 5 mg daily for months and will have test in 1 week!

Can prednisone affect an acth stimulation test? I'm on 5 mg daily for months and will have test in 1 week!

Yes: Normally switch patients to Hydrocortisone for a week before a stim test. It is short acting Prednisone will keep acth suppressed and not allow your pituitary respond to stimulate cortisol production.

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After acth stimulation test confirms adrenal insufficiency does it always need to be treated and/or followed up and how often?

Yes: Adrenal insufficiency means that your body is not able to produce enough steroids. Depending on the cause of adrenal insufficiency, you can be deficient in more than one steroid (cortisol and/or aldosterone). Your body needs these hormones, so it is important to follow-up with your dr. The frequency depends on how stable the disease is for the patient.

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Acth plasma and cortisol blood tests were normal but I have strong addisons symptoms with bronzing. What to do? Should I do an acth stimulation test?

Not an issue for: Self diagnosis. I trust that you are under the care of an endocrinologist, if not, it would be prudent to consult one and follow his/her advice.

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Serum cortisol 145 ng/ml, acth plasma 25. I have skin bronzing since two years. Should I do acth stimulation test as well?

No: If it is 14.5 mcg/dl this is normal am cortisol. Bronzing is due to excess acth either from a low cortisol (addison's) or a pituitary or ectopic tumor making too much acth and elevated cortisol. See an endocrinologist.

Dr. Eric Weisman
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Adrenocorticotropic Hormone (Definition)

It is one of several pituitary hormones - acth for short (the others control the thyroid gland, gonad glands, and others) that controls adrenal gland function in primarily making the hormone called cortisol (not to be confused with "adrenaline"), though the adrenal gland also ...Read more