Top
20
Doctor insights on: Interleukin 6

Share
1

1
CML 10/12. Gleevec .5 log at 6 mths. Sprycel (dasatinib) .5 log at 6 mths. Stem cell transplant 4/14. 7/14 Blast crisis - 65% blast BM + Aspergillus F lung Help?

CML 10/12. Gleevec .5 log at 6 mths. Sprycel (dasatinib) .5 log at 6 mths. Stem cell transplant 4/14.  7/14 Blast crisis - 65% blast BM + Aspergillus F lung Help?

Difficult case: it is a complicated case obviously. first and foremost the infection has to be treated. i would suggest you to follow up with ID and oncologist very closely. importantly is to check if there is certain mutation like T315i mutation as this mutation is resistant to gleevec, sprycel, tasigna (nilotinib) - and should be treated with ponatinib or aurora kinase inhibitor etc. discuss with oncologist. God bless ...Read more

Dr. Sewa Legha
13 doctors shared insights

Aldesleukin (Definition)

Aldesleukin is a cancer-related immune system affecting agent which is a ...Read more


2

2
Why is interleukin important?

Why is interleukin important?

Interleukins: One of a large group of proteins produced mainly by t cells and in some cases by mononuclear phagocytes or other cells. Interleukins participate in communication among leukocytes and are important in the inflammatory response. Most interleukins direct other cells to divide and differentiate. Each acts on a particular group of cells that have receptors specific to that interleukin. ...Read more

3

3
Are the WBC results 15.6, 14.4, 11.4, 13.5, 12.7, 16.7, 14.4 13.3, 12.4, 15.3, 13.9, 14.4 & 17.8 slightly, moderately or highly elevated in general?

Are the WBC results 15.6, 14.4, 11.4, 13.5, 12.7, 16.7, 14.4 13.3, 12.4, 15.3, 13.9, 14.4 & 17.8 slightly, moderately or highly elevated in general?

Blood tests: There are a few diseases that leap out from blood tests. Most of the time, however, blood tests don't tell the doctor much on their own. These results fall into the second group. Good health to you. It is reassuring that the results do not consistently keep rising. ...Read more

4

4
Are there different kinds of pregnancy tests?

Are there different kinds of pregnancy tests?

Yes: Most currently available pregnancy tests are about the some. Dsome of them are for testing urine and some are for testing blood. ...Read more

See 1 more doctor answer
5

5
Is interleukin 6 (IL-6) elevated in lymphoma?

Is interleukin 6 (IL-6) elevated in lymphoma?

IL6 : IL6 is a blood marker of inflammation . It can be seen elevated in some cases of lymphoma or be elevated in other medical conditions not necessarily lymphoma. ...Read more

6

6
Is Interleukin IL-6 typically elevated with advanced stage lymphoma???

Is Interleukin IL-6 typically elevated with advanced stage lymphoma???

Lymphoma: If you have advanced stage lymphoma, the IL-6 level will not make or break the diagnosis. IL-6 is an inflammatory cytokine and anything from infection to arthritis can increase levels. ...Read more

7

7
Why is interleukin important?

Interleukins: One of a large group of proteins produced mainly by t cells and in some cases by mononuclear phagocytes or other cells. Interleukins participate in communication among leukocytes and are important in the inflammatory response. Most interleukins direct other cells to divide and differentiate. Each acts on a particular group of cells that have receptors specific to that interleukin. ...Read more

8

8
What are EPO and interleukin-11?

What are EPO and interleukin-11?

Important proteins: Epo (erythropoietin) is a key hormone (made by kidneys in adults, liver in babies) in stimulating/signalling the production of red blood cells--it is used to treat anemia in folks wth kidney failure. Interleukin-11 is a cellular protein encoded by the gene il-11 and is important is regulation of a megakaryocyte--the cell which makes platelets. Very complex processes. Have fun learning. Good luck. ...Read more

9

9
What is interleukin 12?

What is interleukin 12?

Signaling molecule: Interleukin-12 (il-12) is known as a cytokine, which are small cell-signaling protein molecules that are secreted by numerous cells and are used extensively in intercellular communication. Il-12 is secreted by certain types of immune cells (such as dendritic cells) to regulate other members of the immune cells (for example, natural killer (nk) cells). ...Read more

10

10
Does interleukin inhibit or turn down the immune response?

Does interleukin  inhibit or turn down the immune response?

Interleukins: One of a large group of proteins produced mainly by t cells and in some cases by mononuclear phagocytes or other cells. Interleukins participate in communication among leukocytes and are important in the inflammatory response. Most interleukins direct other cells to divide and differentiate. Each acts on a particular group of cells that have receptors specific to that interleukin. ...Read more

11

11
Is interleukin-1 increased in fever?

Is interleukin-1 increased in fever?

IL 1: Interleukins are cytokines. These are chemical substances released by one cell (often inflammatory), which influence the behavior of other cells. Several interleukins, particularly il 1, are known as pyrogens, in that they may induce fever. Since the interactions among these are quite complex it is possible that the fever was induced by one pyrogen which also caused release of il 1. ...Read more

12

12
What makes interleukin-2 and what makes interferon gamma? Are they both made by t-lymphocytes?

What makes interleukin-2 and what makes interferon gamma?  Are they both made by t-lymphocytes?

Yes: Interleukin 2 (aldesleukin) is made by t-cells and is important for the growth of other t-cells. Interferon gamma is made by both t cells and natural killer cells and is part of the innate immune response. ...Read more

13

13
Results of trial of proleukin (aldesleukin) in recent onset type 1 diabetes?

Results of trial of proleukin (aldesleukin) in recent onset type 1 diabetes?

Ongoing Study: According to clinicaltrials.Gov, the phase i trial is still on-going; there are no results yet. ...Read more

14

14
Can phase I trial of proleukin (aldesleukin) and Rapamune lead to type 1 diabetes?

Can phase I trial of proleukin (aldesleukin) and Rapamune lead to type 1 diabetes?

NIH study: The combination of these drugs is being studied in adult patients already diagnosed with type 1 diabetes. The thought is that the combination might help slow down the progress of diabetes. The study isn't complete yet. If there is another phase 1 trial using these drugs in a different study, the investigator should be approached with your question. ...Read more

15

15
Phase I trial of proleukin (aldesleukin) and Rapamune in recent onset type 1 diabetes, what to do?

Phase I trial of proleukin (aldesleukin) and Rapamune in recent onset type 1 diabetes, what to do?

Phase I trials: This is a question best asked of your endocrine specialist. I suppose you are contemplating entering the trial? Do your research and make sure that your questions are answered, be sure that you are willing to make the necessary time commitment. Discuss with family and trusted peers/friends before deciding to join a study. http://clinicaltrials.gov/show/NCT00525889 ...Read more

16

16
Any good results from the phase I trial of proleukin (aldesleukin) and Rapamune in recent onset type 1 diabetes?

Any good results from the phase I trial of proleukin (aldesleukin) and Rapamune in recent onset type 1 diabetes?

Probably not: It appears that a phase 1 trial of these medications was attempted in 2007, but results were never published. This probably means that the trial was abandoned. Years ago, another immunosuppressive med was used (cyclosporin) to treat early Type 1 diabetes and was successful in preserving pancreatic function. However further studies were abandoned because of excessive toxicity of this class of med ...Read more

17

17
Can i show at 6 weeks?

maybe your: Waist may be thicker. Really - would not show much at this point. ...Read more

18

18
2-6/HPf(1+) wat does it mean?

2-6/HPf(1+) wat does it mean?

Microscopy: This is saying that 2-6 cells were seen in one high-power field (hpf). And that correlates to a 1+ rating. I'm assuming this is on a urinalysis, but it could be on a number of other tests as well. Hope this helps!! ...Read more

19

19
2-6/HPf(1+) wat does it mean?

2-6/HPf(1+) wat does it mean?

Microscopy: This is saying that 2-6 cells were seen in one high-power field (hpf). And that correlates to a 1+ rating. I'm assuming this is on a urinalysis, but it could be on a number of other tests as well. Hope this helps!! ...Read more

20

20
How can I grow 3-6 inches taller?

How can I grow 3-6 inches taller?

Puberty: If you are still in puberty - growth spurts are still possible. However after you reach adulthood there are no ways to make yourself grow taller. If you had a specific medical condition that stunted your growth that might respond to appropriate treatment. Our height is determined primarily by genetics. ...Read more