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Doctor insights on: Interferon Injections For Melanoma

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How effective are interferon alfa-2b injections for treating melanoma?

How effective are interferon alfa-2b injections for treating melanoma?

Moderate: Alfa interferon was introduced to help control metastatic melanoma. The dose however is extremely high and given over a several week period of time. With the introduction of the checkpoint inhibitors such as anti CTLA4 and the PD-1s along with the interleukins there is better control being employed than with the interferons which do help in expressing the tumor protein more effectively. ...Read more

Interferon (Definition)

Interferons are a diverse group of proteins that belong to a class of glycoproteins known as cytokines. Interferons were first discovered for their ability to block viral replication within host cells. They also have been found to activate immune cells for many disease processes. There are several classes of interferons, types i, ii and iii, depending on ...Read more


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Has anyone used peginterferon alpha 2B and temezolomide for melanoma?

Has anyone used peginterferon alpha 2B and temezolomide for melanoma?

Alone or in combo?: Both of these drugs have been used separately to treat metastatic or high risk melanoma. However, the combination of these two drugs must be considered experimental, without even knowledge of safe doses let alone efficacy. ...Read more

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How effective are Cetuximab injections for treating colon cancer?

How effective are Cetuximab injections for treating colon cancer?

Some response: Erbitux was one of the first monoclonals develoed. It targets epidermal growth Factor 1 and is used in metastatic colon Ca that has the wild mutated KRAS. The best response is like Herceptin (trastuzumab) where this epidermal growth factor 2 mAb requires added chemo. As such when Colon Ca is treated with Erbitux + chemo there is an improvement in response for a number of months. No cures have been seen. ...Read more

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How effective are Bleomycin injections for treating leukemia?

How effective are Bleomycin injections for treating leukemia?

No good!: Bleomycin is not a good diagnosis for treating Leukemia. It is often used for treating Lymph gland cancer(Hodgkin Disease). So you need to confirm your exact diagnosis before you get concerned with this response. ...Read more

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How effective are Leucovorin injections for treating colon cancer?

How effective are Leucovorin injections for treating colon cancer?

Not anti tumor: Leukovorum is used as an adjuvant or modifier of single or combinations of chemotherapeutic agents. It helps to prevent the toxic side effects of a number of chemotherapeutic agents including methotrexate. It also can be used to treat anemia caused by a lack of folic acid. It is added to combination of drugs employed in the supportive care of patients with colon cancer but does not have anticancer effects on diseases such as colon cancer, . ...Read more

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Are imuran (azathioprine) & betaferon effective treatments for ms?

Are imuran (azathioprine) & betaferon effective treatments for ms?

Yes they can be: The evidence is stronger for beta interferons (avonex, Rebif and betaseron) than it is for immuran. Interferons are fda approved and immuran is not (for ms) they all have a modest but definite effect in reducing the number of attacks in remitting relapsing forms the effect varies from patient to patient. ...Read more

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How effective are Irinotecan injections for treating colon cancer?

How effective are Irinotecan injections for treating colon cancer?

Pretty good: Usually they're part of a protocol. If I were offered this as adjuvant Rx and it was affordable from my end, I'd probably go ahead if it was offered by an ethical oncologist. I'd quit if it was clearly not helping. ...Read more

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How effective are interferon alfacon-1 injections for treating hepatitis C?

How effective are interferon alfacon-1 injections for treating hepatitis C?

Not Very: The interferons are not very effective for treatment hepatitis C. Depending on the type (genotype) of hepatitis C, the cure rate ranges from about 30% to 75% at best. There are now newer medications called Direct Acting Antivirals which are much more effective and have fewer side effects than the interferon medications. ...Read more

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How effective are Filgrastim (filgrastin) injections for treating leukemia?

How effective are Filgrastim (filgrastin) injections for treating leukemia?

Filgrastim (filgrastin): "Filgrastim is used to decrease the chance of infection in people who have certain types of cancer and are receiving chemotherapy medications that may decrease the number of neutrophils (a type of blood cell needed to fight infection), in people who are undergoing bone marrow transplants, and in people who have severe chronic neutropenia (condition in which there are a low number of neutrophils > ...Read more

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How effective are interferon alfa-2b injections for treating hepatitis C?

How effective are interferon alfa-2b injections for treating hepatitis C?

Treating Hep C: There are quite a number of totally oral (pill) regimens for treating Hep C, such that interferon is hardly ever used anymore. Not sure who is trying to give that to you, but you may want to get a second opinion. Interferon can be rough treatment -alot of patients struggle with the side effects. Interferons are good antiviral medicines, but there's alot of alternatives these days for Hep C. See MD ...Read more

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How effective is avastin (bevacizumab) as targeted therapy for the metastatic colorectal cancer?

How effective is avastin (bevacizumab) as targeted therapy for the metastatic colorectal cancer?

See below: It is not a curall for colon cancer but is effective therapy to a large extent it depends onthe size and wehre it is. Almost certianly it requires more than this drug to get a cure if acure is possible. ...Read more

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For a synovial sarcoma are imatinib or everolimusm effective?

For a synovial sarcoma are imatinib or everolimusm effective?

These have no: Established role in front line therapy. Are they being offered on a clinical trial? Both are costly, and possibly of theoretic use. Ask for the strength of the data (it will be called a phase ii trial), . ...Read more

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Patients with advanced breast cancer,Has received chemotherapy,Is there any need for radiotherapy?

Patients with advanced breast cancer,Has received chemotherapy,Is there any need for radiotherapy?

Breast Cancer: As you see on TV cancer Dx and Rx is very individualized. Some need radiation and some may not. So discuss this with your Dr. ...Read more

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Best first-line treatment for mantle cell lymphoma now: high doses of ara-c+rituximab and autologous sc transplant, or rituximab+bendamustine?

Best first-line treatment for mantle cell lymphoma now: high doses of ara-c+rituximab and autologous sc transplant, or  rituximab+bendamustine?

There is no: Definitive answer to your question. Studies have compared the strategies you mention. The high dose ara-c arm was closed because it was difficult to mobilize stem cells for transplant after these regimens. Bendamustine-r is a good program, and many centers would consolidate a good response with an autograft. ...Read more

Dr. Mike Bowman
957 doctors shared insights

Skin Cancer (Definition)

A condition in which some element of your skin--which is one of the most complex organs in the body--degenerates into cancer. The three most common types of skin cancer are: basal cell, squamous cell, and melanoma which occur in that order and degree of aggressiveness. Although heredity plays a major role, sun exposure and tobacco use and ...Read more


Dr. Travis Kidner
2,633 doctors shared insights

Melanoma (Definition)

Cancer of the melanocyte cells. Melanocyte cells determine the color of your skin. Although these cells are primarily found in your skin, they can also be found in the bowel ...Read more