Doctor insights on:
Interferon Alfa 2b And Ribavirin Medication
Interferons are a diverse group of proteins that belong to a class of glycoproteins known as cytokines. Interferons were first discovered for their ability to block viral replication within host cells. They also have been found to activate immune cells for many disease processes. There are several classes of interferons, types i, ii and iii, depending on ...Read more
Contraindications: See list of contraindications at: https://dailymed. Nlm. Nih. Gov/dailymed/archives/fdaDrugInfo. Cfm? Archiveid=12503 ...Read more
Interferon alpha: Is a treatment for chronic hepatitis c and is also occasionally used in certain types of lymphoma and leukemia. It is a manufactured protein that is derived from a real human protein. There are some very significant side effects that include severe flu-like symptoms, depression, nausea, diarrhea, headaches. ...Read more
Interferon alfa-2b: Interferon Alpha 2b, made from recombinant dna, used in the treament of several illnesses. A poor name -- an intron is defined to be a portion that is transcribed by messenger RNA but then the corresponding portion of messenger RNA is removed by RNA splicing before translation. ...Read more
Moderate: Alfa interferon was introduced to help control metastatic melanoma. The dose however is extremely high and given over a several week period of time. With the introduction of the checkpoint inhibitors such as anti CTLA4 and the PD-1s along with the interleukins there is better control being employed than with the interferons which do help in expressing the tumor protein more effectively. ...Read more
Treating Hep C: There are quite a number of totally oral (pill) regimens for treating Hep C, such that interferon is hardly ever used anymore. Not sure who is trying to give that to you, but you may want to get a second opinion. Interferon can be rough treatment -alot of patients struggle with the side effects. Interferons are good antiviral medicines, but there's alot of alternatives these days for Hep C. See MD ...Read more
Google it: Since I don't know what specific information you need, it is difficult to answer in a concise manner given the limitation of our responses. Honestly I would "google it" as there are a lot of medical and non medical topics that might help you. If you have further specific questions, I would be happy to answer. ...Read more
Many; see below: Many of patients experience flu-like symptoms like fever, chills, headache, fatigue, and weakness within 1-2 hours of taking the medication. Symptoms like irregular heartbeat, chest pressure or tightness, hallucinations, irritability, insomnia, depressive mood, and suicidal thoughts may also occur. It’s important to report any of these to your doctor. ...Read more
Effective: There is better treatment nowadays with lamivudine or better tenofovir ...Read more
Interferon: Intron a (interferon alfa 2b) is the trade name for interferon alpha. Not used as much as in the past, but still can be used for high risk melanoma, rarely for some myeloproliferative neoplasia situations and renal cell cancers. Most common use is in hepatitis c. Interferon is a natural substance made by lymphoid cells in response to viral and other illnesses. ...Read more
For HCV?: Interferon gamma and Ribavirin has been the standard of care for treatment of hepatitis c virus infections. Success rates have been poor, however. Newer antiviral agents are now available and being used in patients who did not have successful treatment with interferon and ribavirin. You should talk to your doctor about new options. ...Read more
Lots...: Fatigue, headache, rigors, fever, insomnia, irritability, depression, dizziness, impaired concentration, anxiety, emotional lability, hair loss, pruritus, dry skin, rash, nausea, anorexia, weight loss, diarrhea, vomiting, abdominal pain, anemia, injection site reaction, muscle and joint pains, shortness of breath, cough, flu-like symptoms, birth defects, chest pain, suicidal behavior to start. ...Read more
Depends: That depends on which genotype of hcv you have. In general, it's easier to cure hepatitis c with a combination of interferon, ribavirin, and an hcv protease inhibitor than with interferon and Ribavirin alone. However, there are some hcv genotypes that have a high cure rate without the protease inhibitor. ...Read more
Question regarding pegylated interferon injections and ribavirin treatment. Who does them and when?
I have beta-thalassemia and HCV. I was on interferon with ribavirin in 2008. It didn't work. Now I want to try Sovaldi. What are my chances it works?
Worth the try: It's looking really good. I hope you are able to get it. The politics of availability are bizarre -- I feel the drug company needs to see a fair profit that will allow more work, and that the people whose taxes paid for the basic research aren't denied a great medicine. Keep reading the blogs and find out the best way for you to get access to the real stuff at reasonable cost. ...Read more
Going through interferon and ribavirin trtmt for hepc, labs show very low platelet count what does that mean?
Known side effect: Bone marrow suppression is a known side effect of your treatment. Low platelet counts are usually not problematic unless the count falls below 40, and in some patients a count as low as 10 may not cause problems. Blood counts are usually monitored during treatment and you should discuss your concerns with your doctor. ...Read more
What are relapse symptoms after triple therapy (ribavirin, peg-interferon, incivek) for hepatitis c? Very worried about relapsing at the moment!
Hep c: Hep c is hard to treat and as you know, the treatment is hard to tolerate. Symptoms of relapse would include jaundice, but a better way is to just get a viral load checked with a blood test. That would tell you a lot more. ...Read more
I am on interferon/ribavirin and was curious how to keep my lymphatic system in good shape? My lymph glands in my neck gets swollen from time to time?
I'm going through interferon and ribavirin treatment for hep c, can it weaken my immune system and make it easier for me to catch colds, etc?
Can: Any time you are on biologics such as interferon you place yoursef at risk so any time you get sick or bhave fevers seek medical opinion. ...Read more
Will I be able to drink alcohol while taking the medications ribavirin and peg intron (peginterferon alfa 2b)?
This a site for medical answers and not legal
when you are adviced to take this medicine there is a warning given to the person that they should practce birth control and and you or your sexual partner if you are a male have to have a pregnancy test done before starting on this medicine as it can cause birth defects or loss of fetus, and don't get pregnant for six monyhs after stopping the treatment. ...Read more
# OF INJECTIONS: Both Avonex and Copaxone are drugs of the 90's, and have helped numerous pts. Copaxone is injected daily, does have injection rxtns, yet is considered safer for pregnancy. Avonex is injected once weekly, but can cause flu rxtns, depression, thyroid and liver issues, and is not safe for pregnancy. Both are modestly effective, but many newer agents have better outcomes (tysabri, gilenya, (fingolimod) etc). ...Read more
Avonex (interferon beta 1a) v Copaxone: Avonex (interferon beta 1a) is an injection given to a muscle once per week. It is a deep shot. Copaxone is a superficial shot given under the skin every day. The retail costs of the medicines are about the same. They are both expensive; insurance coverage may be important. Avonex (interferon beta 1a) sometimes may cause flu-like side effect symptoms, copaxone may not. Both can cause irritation by the injection site. ...Read more