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Doctor insights on: Interaction Zoloft Sertraline

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What are the interactions between Zoloft (sertraline) and melatonin if any?

What are the interactions between Zoloft (sertraline) and melatonin if any?

Zoloft/Melatonin: No interactions. Only caution when taking melatonin is if u r on medications that suppress the immune system, blood thinners, diabetes medications, & birth control pills. ...Read more

Dr. Heidi Fowler
1,094 Doctors shared insights

Sertraline (Definition)

Also called zoloft, (sertraline) is one of selective serotonin reuptake inhibitors, with antidepressant/anti-anxiety actions. May cause headaches, nausea & ...Read more


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I take zoloft, (sertraline) are there any interactions between Zoloft (sertraline) and herbalife shakes?

I take zoloft, (sertraline) are there any interactions between Zoloft (sertraline) and herbalife shakes?

Zoloft (sertraline) and herbs: When taking zoloft, (sertraline) be careful not to take St John's wart ginkgo biloba, 5 ht and l-tryptophan as they can increase serotonin. Check if herbalife products contain these ingredients. ...Read more

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Does Zoloft (sertraline) cause weight gain? Are there any interactions with Zoloft (sertraline) and st. John's wort?

Does Zoloft (sertraline) cause weight gain? Are there any interactions with Zoloft (sertraline) and st. John's wort?

Probaly Not: There is no strong association between zoloft (sertraline) and weight gain but depression can cause loss of appetite and treatment may cause it to return.
Do not take st. Johns wort, its affects are additive to zoloft (sertraline) and might cause a condition called serotonin syndrome or neuroleptic malignant syndrome. ...Read more

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There any interaction between Zoloft (sertraline) 50mg and Risperdal 0.25 and remeron 15mg?? And can bi combine together?

There any interaction between Zoloft (sertraline) 50mg and Risperdal 0.25 and remeron 15mg?? And can bi combine together?

Discuss w/ provider: Hopefully the same doctor prescribed these or they consulted if it was not. There is a potential problem (serotonin syndrome) when Zoloft (sertraline) and Remeron are taken in combo. So, make sure this is the best treatment plan available to you since it needs close monitoring. They all interact w/ each other in a non-major way that can increase dizzy, drowsy, confused effects so be careful w/ what you do. ...Read more

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I am worried about the interaction of Zoloft (sertraline) and elavil, the drowsiness does not bother me as a matter of fact better rest is welcome.

I am worried about the interaction of Zoloft (sertraline) and elavil, the drowsiness does not bother me as a matter of fact better rest is welcome.

One too many: Taking two serotonergic drugs with similar mechanism of action is generally not advisable. Serotonin syndrome which can be seriously life threatening may occur. Talk with you doctor about getting on one serotonin drug. ...Read more

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I don't trust my doctor for certain reasons and I wanted to know what are the phenylpiracetam interactions with lithium, zoloft, (sertraline) risperidal, and artane?

I don't trust my doctor for certain reasons and I wanted to know what are the phenylpiracetam interactions with lithium, zoloft, (sertraline) risperidal, and artane?

Second opinion: The doctor patient relationship is very important. You can start w/getting a second opinion from another doc. If you are more comfortable w/second or even third doc, then stay w/him or her. If you don't trust any doc then you would do well to sort that out w/a therapist. Peace and good health. ...Read more

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My psychiatrist is away for a while and I wanted to know what are the phenylpiracetam interactions with lithium, zoloft, (sertraline) risperidal, and artane?

My psychiatrist is away for a while and I wanted to know what are the phenylpiracetam interactions with lithium, zoloft, (sertraline) risperidal, and artane?

Med Interaction: Perhaps one of the psychiatrists here can take this question. If they don't contact who ever may be taking call for your reg. Psychiatrist. Drs generally have another dr. Cover for them while they are out of town. ...Read more

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Do you think taking Le-Vel Thrive and Zoloft (sertraline) at the same time would cause interactions?

Unknown interactions: Le Vel Thrive is a product marketed to promote weight loss, energy and improved mood and focus. It reportedly contains vitamins, minerals, herbal supplements, enzymes and antioxidants designed to produce lean muscle and mental clarity. However, such claims have not been endorsed by the FDA. This means that there may be unknown adverse interactions if taken with antidepressants such as Zoloft (sertraline). ...Read more

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Seretide acuhealer 125 mg x2 a day + Zoloft (sertraline) 200mg if no interactions?

Seretide acuhealer 125 mg x2 a day + Zoloft (sertraline) 200mg if no interactions?

Med Interactions: There is no specific contraindication and I would assume your doctor who prescribed is aware of your other medications. If you are still worried, please ask the prescribing doctor since they know you best and the reason (s) for prescribing your medications. ...Read more

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I'm prescribed 50mg of Zoloft (sertraline) and 10mg daytrana. Should I worry about the interactions of the three?

I'm prescribed 50mg of Zoloft (sertraline) and 10mg daytrana. Should I worry about the interactions of the three?

Zoloft/daytrana: Daytrana and zoloft (sertraline) are often prescribed together. The only interaction is that Daytrana can increase zoloft (sertraline) levels in the blood. This varies from person to person. If you have a mood disorder and adhd, you also need to consider the treatment for adhd can worsen your mood. If you have both issues, I would recommend that you see a psychiatrist who can treat both and be aware of conflicts. ...Read more

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I am presently taking Risperdal and now I am being put back on my Zoloft (sertraline) should I worry bout any interactions?

Not particularly: Should not be much to worry about with risperidone. Technically both work on the aspects of the serotonin system but should not affect how each other are broken down. I am not aware of any absolute contraindications of being on both ...Read more

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Does Zoloft (sertraline) and Doxycycline have any interactions?

Does Zoloft (sertraline) and Doxycycline have any interactions?

No: No interactions reported, but always let a prescribing doctor know about your other medications. It really helps them serve you best. ...Read more

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I take lopressor 37.5 mg and zoloft (sertraline) 25mg. Is it safe to use together, like there is now interactions?

I take lopressor 37.5 mg and zoloft (sertraline) 25mg. Is it safe to use together, like there is now interactions?

Discuss w/ Dr: Zoloft (sertraline) can exaggerate the effects of the lopressor so it's important for your doctor to check you more frequently to be sure dosage is appropriate. Work together on any combinations of medications to be safe. Best! ...Read more

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Would any type of birth control (besides only condoms) be safe to use or take while I am taking zoloft (sertraline)? I absolutely don't want bad interactions.

Would any type of birth control (besides only condoms) be safe to use or take while I am taking zoloft (sertraline)? I absolutely don't want bad interactions.

Birth control on zol: Antidepressants decrease the effectiveness of birth control, but fortunately zoloft and wellbutrin (bupropion) effect it the least. I suggest you use a backup method with oral contraceptives while on an antidepressants, maybe an iud or a vaginal condomn, or your partner use a condomn. ...Read more

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Can I take valerian root at night before bed while taking 25mg Zoloft (sertraline) daily? Is it safe? Or are there interactions?

Can I take valerian root at night before bed while taking 25mg Zoloft (sertraline) daily? Is it safe? Or are there interactions?

Be careful: As you say you'd be taking the Valerian at bedtime, the fact that the combo can cause drowsiness, inability to concentrate and dizziness may not be too disturbing - but it can also increase a risk of respiratory depression - so if you have any breathing issues I'd avoid it and if you feel even a bit of such problems cease use immediately. I'd try warm milk or a boring book instead. Best! . ...Read more

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Will there be a Zoloft (sertraline) and metoprolol tartrate interaction?

Will there be a Zoloft (sertraline) and metoprolol tartrate interaction?

Possibly: Sertraline may potentiate the effect of metoprolol. It may cause the heart to beat at a slower rate than normal. Symptoms of this condition include dizziness, chest pain, and fainting. ...Read more

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Can I drink chamomile tea with Zoloft (sertraline)? Is there an interaction? I know St. John's Wort is off limits :) Is chamomile safe?

Yes it is: The St. John's is more of a theoretical. Although it (but not chamomile) lowers liver metabolism of drug, it is not a strong blocker of liver metabolism, and the safety margin of Zoloft (sertraline) is quite high (double the amount is still safe in most). ...Read more

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Can I take generic pepto with an ssri? I am taking Zoloft (sertraline) and it is causing me awful nausea. I have a bottle of generic pepto bismol in my dorm room... Can I take that without having a problematic interaction?

Can I take generic pepto with an ssri? I am taking Zoloft (sertraline) and it is causing me awful nausea. I have a bottle of generic pepto bismol in my dorm room... Can I take that without having a problematic interaction?

Sertraline: Sertraline (zoloft) potentiates bleeding. So if there any concern over an ulcer it would not be safe. A safer choice may be to get a prescription for zofran (ondansetron) (odansetron) from student health. That is orally absorbed and safe to take for nausea. ...Read more

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I take Zoloft (sertraline) and clonazepam is it ok to take my atenolol and melatonin at night the Zoloft (sertraline) side interactions said no. Advise thanks?

I take Zoloft (sertraline) and clonazepam is it ok to take my atenolol and melatonin at night the Zoloft (sertraline) side interactions said no. Advise thanks?

Yes it's ok: There are no known interactions between the medications you list other than when combined they can make you sleepier than with just one of them. ...Read more

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Drug interactions with niacin atenolol vit c magnesium iron Zoloft (sertraline) melatonin and armour?

Epocrates check: A quick check on my trusty med database program reveals 3 main negative interactions with those meds listed. Two of them are with armour. The armour interacts with both the iron and magnesium making the thyroid med less absorbed, so separate these vitamins from your armour by at least 4 hrs. The other major interaction is atenolol and niacin. Less cholesterol lowering effect and overlowering of bp. ...Read more

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I was prescribed Zoloft (sertraline) and don't want it. Can I pour it down toilet?

Talk to your doctor: First, it is not a good idea to flush meds down the toilet due to filtration and sanitation concerns. It is best to have your physician's office, pharmacy or the police station dispose of them properly. As far as discontinuing zoloft (sertraline) on your own, I would strongly recommend that you speak with your doctor about your concerns with yhe med. ...Read more

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Will Zoloft (sertraline) help will obsessive harmful thought s that won't go away?

Will Zoloft (sertraline) help will obsessive harmful thought s that won't go away?

Maybe.: Sertraline is a reasonable drug to consider. It has more than a fair chance of working for you. ...Read more

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What should I do if I haven't felt any change after taking Zoloft (sertraline) for almost 4 weeks?

What should I do if I haven't felt any change after taking Zoloft (sertraline) for almost 4 weeks?

See your doctor: Like all antidepressants, it may take 4-6 weeks to feel the full benefit, but you should see at least some benefit within a couple of weeks zoloft can be dosed up to 150 mg so if you are on a lower dose, the dose can be increased. If you are already on150 mg then it is time to consider another antidepressant or adding abilify, (aripiprazole) wellbutrin, or Remeron to supplement the effects of the zoloft. ...Read more

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Does Zoloft (sertraline) make you gain weight? I've put on 30 lbs in two months and I can't loose it

Does Zoloft (sertraline) make you gain weight? I've put on 30 lbs in two months and I can't loose it

Zoloft (sertraline) weight gain: Some people are very sensitive to mental medicines and would gain weight even with meds that are not kwown to make people gain weight. If you already have a weight issue and cannot lose weight easily, zoloft (sertraline) can also cause you some weight gain even thought it causes the least of that.
If you already have a healthy lifestyle, please make it better, if not then try to adopt a healthy one. ...Read more

Dr. Alan Ali Dr. Ali
1 doctor agreed:
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I feel like I've lost myself while being on Zoloft (sertraline) but I can't stop taking it what should I do?

Dr. Alan Ali Dr. Ali
1 doctor agreed:

Zoloft (sertraline): Not sure what dose u r taking & whether your symptoms started after increasing the dose, but I recommend reviewing those possibilities with your prescribing doctor to see if lowering the dose might be an option. ...Read more

Dr. Heidi Fowler
1,048 Doctors shared insights

Zoloft (Definition)

Zoloft is a serotonin reuptake blocker which is a kind of ...Read more


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