Doctor insights on:
Insulin Other Pancreas Makes Important
Insulin dependent diabetes: is there any other treatment to reactivate pancreas to generate insulin?
Abdominal organ. It is digestive organ: it secretes enzymes into the small bowel which break down food and help its absorption. It is also an endocrine organ: it produces hormones involved in sugar control and control of digestion. Insulin is one of these hormones. Diabetics either lack Insulin (type 1 diabetes) or have inadequate ...Read more
Absolutely: The pancreas has a dual role as both an endocrine and exocrine organ. Aside from insulin, other pancreatic endocrine hormones like glucagon and somatostatin are responsible for controlling your body's blood sugar. The exocrine pancreas is vital in producing enzymes to help digest carbs, proteins, and fats in the intestine. Otherwise, you'd have severe malabsorption of nutrients. ...Read more
Does metformin regulate glucose made by liver? What's best way to treat diabetics, control liver glucose production or pancreatic insulin production?
Yes but there's more: One of metformin's actions is reducing liver glucose production. It also helps improve the body's use of insulin, aka Insulin sensitivity. This is key to long term health with diabetes. Eating smart, exercise, and keeping to a good weight also help. Metformin is our usual first choice & meds that increase pancreatic Insulin production are not , but you & your doc must pick what's best for you. ...Read more
Is diabetes mellitus 1 characterized as the inability of the pancreas to produce sufficient insulin?
A key issue, but No: Glucose control is complex & Insulin is only one of many controls involved, but insufficient ouput is basis for DX of type 1, <35 to 45 units/24 hrs, easily checked by checking c-peptide production. Insulin always secreted with amylin, available as symlin (pramlintide), (pramlintide) thus stopping all carbs & adding symlin (pramlintide) can markedly help. Other issues: body fat (binds insulin), muscle mass, adrenalin, gh, resistin, glp-1. ...Read more
Is it possible that taking unneeded insulin confuse a person's pancreas or make it "lazy" ultimately leading to diabetes?
Since all cells require insulin, do the BETA CELLS of the pancreas (beta cells make insulin) give themselves insulin? How does it work?
Is it real that januvia (sitagliptin) 100mg made pancreas cells produce more insulin ( made beta cells more active )?
Incretin: Januvia (sitagliptin) is an incretin which inhibits the breakdown of an enzyme called dpp-4. Dpp-4 breaks down glp-1. Glp-1 stimulates Insulin and inhibits glucagon (which raises glucose). Inhibition of glp-1 breakdown means it can stimulate more Insulin and inhibit more glucagon. ...Read more
What are the pros and cons of an insulin pump? Does it keep a diabetic type 1 insulin in better check? No other health problems.
appropriate for some: Insulin pump is a great tool to control both type 1 and type 2 diabetes and it is commonly used. However, not all patients are candidates for the Insulin pump. The only way to know is to have a discussion with your physician about your appropriateness for an Insulin pump. ...Read more
PCOS sometimes is related to insulin resistance,what are the required tests to diagnose such insulin resistance?
Muscle wasting, eating plenty,insulin resist. pancreatic beta cell dysfunction fructosamine and post prandial high, insulin level @2 what does it mean?
Complex interaction: Phosphoprotein phosphatase is activated by the insulin, which indicates that there is a high concentration of glucose in the blood. The enzyme then acts to dephosphorylate other enzymes. The net effect is for glucose to enter the cell where it can be metabolized andlalso lowers the serum glucose level. ...Read more
Insulin pump: It is a good insulin pump, and many users like it. However, an insulin pump often does not solve your blood sugar issues. It requires a lot of care, and you still need to check your glu many times per day. If you are thinking about a pump, you should be talking to an endocrinologist who uses a lot of pumps and who can guide you through this. ...Read more
Lifestyle change : Even for patients on medication for diabetes or metabolic syndrome, a healthy diet accompanied by weight loss, exercise, and quality sleep (or treated obstructive sleep apnea), is the key to getting back on track. For those already on medication, doctors may even be able to decrease doses once the effects of lifestyle change start happening. A healthy lifestyle involves a lifelong commitment. ...Read more
Could pancreatic insufficiency be linked with trouble digesting sugars (bc of amylase), or only lipids?
Chronic pancreatitis: Chronic pancreatitis is hallmarked by problems absorbing fats (greasy, floating stools, sometimes gray or chalky). Problems with sugar metabolism come later as more of the pancreas is damaged. Chronic pancreatitis is further characterized less by low amylase production and more with lack of Insulin production and associated problems with glucagon. ...Read moreSee 1 more doctor answer
Be good 2your liver: Insulin causes skeletal muscle and fat cells to absorb blood glucose. This glucose often comes from the liver after glycogenolysis. This is the breakdown of glycogens, which are the sugars your liver stores in long chains to use later. the release of blood sugar from these glycogen chains is done via the enzyme glycogen phosphorylase. ...Read more
Yes: Igf-1 is a potent glucose lowering agent , in fact the new Insulin analogs Humalog (insulin lispro) and NovoLog have alterations in one of the Insulin components that were derived from the observation that when igf-i was injected through the skin it lowered the sugar faster than regular insulin. ...Read more
Is it possible for a person to get both diabetes type 1 and 2? As in, the insulin receptors become so irresponsive that blood glucose levels rise twice as rapidly?
Yes and no: Patients with type 1 diabetes who develop Insulin resistance requiring lots of Insulin have both. It is sometimes referred to as type 1 1/2 dm. Insulin resistance will often accompany obesity, poor diabetes control and high triglycerides, for example. Blood sugars don't "double" in rate, but Insulin doses may go up significantly to maintain control of blood sugars. ...Read moreSee 1 more doctor answer
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