Doctor insights on:
Inoperable Pancreatic Cancer Prognosis
Depends: For the 85% or so of patients who present with disease that cannot be resectable, survival is usually 6 months or less without treatment and around a year with aggressive chemo +/- radiation. Surgery with negative lymph nodes has about a 25% 5-year survival rate with chemo and radiation. Surgery with positive nodes - about 14 months average with chemo and radiation.See 1 more doctor answer
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
My son has pancreatic cancer. It has moved to the lymph nodes. Generally what is the prognosis? He is 39.
Poor: Prognosis is 6-12 months for unresectable adenocarcinoma of the pancreas.
Pancreatic cancer, ampullary tumor. Whipple procedure. Spread to liver, not respectable. Chemo for 6 months and continuing. Prognosis?
Poor: While Whipple is the best approach for a primary pancreatic or ampullary lesion, the recurrence rate at 1-2 yrs is 90%. Chemo either of the FOLFIERI or Genciabine /Abraxane combo have limited effects on liver mets which in pancreas are not considered amenable to resection. There is an FDA protocol using specific monoclonals targeting pancreas that might be available but only after chemo failure
CANCER: Is the DaVinci Robotic System used for pancreatic cancer in any major medical center in the U.S.?
Probable viral: Pancreas cancer starts out as an intraductal lesion similar to breast DTIC (dacarbazine). It smolders within the ductal system for 15-20 yrs before first signs of ductal wall invasion to become an early pancreatic carcinoma. The TAA that are expressed early are oncofetal in origin and are suppressed at birth to reappear in the tumor as the oncogenic protein. Transformation probably viral induced.
Yes indeed: The usual form is pancreatoblastoma, a tumor with a different appearance and behavior from common adult pancreatic cancer. It's quite uncommon, with a few dozen cases in the us each year. A microscopic photo of one such tumor is shown in the picture.
Yes.: But, not unheard of. The typical adenocarcinoma of the pancreas is much more common in middle-aged to elderly patients. There are some other types of cancer, more endocrine in nature, which can occur in younger patients. Make sure you have a discussion with your doctor, who can guide you to a competent surgeon and oncologist, if needed. Good luck.See 1 more doctor answer
Can be: Pancreatic cancer symptoms depend on the extent of the cancer and can range form minimal to very significant in intensity. Typical symptoms include jaundice, abdomen pain (can be severe), bowel obstruction, weight loss, new-onset diabetes, depression, fatigue to name a few.See 1 more doctor answer
Surgery evaluation: Pancreatic cancer is a very aggressive malignancy. A surgical oncologist needs to evaluate the patient to see if the patient has resectable disease and can tolerate the whipple procedure. If the cancer is resectable often radiation and chemotherapy is used afterwards to delay/prevent recurrences. On unresectable patients combinations of radiation and chemotherapy offer some palliation.See 1 more doctor answer
Long incubation: The incubation is very long for the carcinoma in situ. Why after this period of time the invasive lesion is so aggressive is undetermined. Early diagnosis in the incubation period of time can be made with ERCP brushing where the atypical preinvasive cells can be identified. Usually after 15 years the in-situ lesion transforms and invades the ductal wall into the parenchyma to become invasive.
So do we: Pancreatic cancer seems to be a spontaneous event and because it is internal with no early symptoms, is rarely detected until it has spread beyond meaningful treatment. No one knows the cause. There is much investigation being done to provide earlier detection and discover the cause.
Unsure of question!: Do YOU have pancreas cancer? That is very rare in someone in their 30s. No one knows what causes pancreas cancer. Symptoms are usually upper mid-abdominal pain near the breast bone, often after eating going into the back, weight loss, loss of appetite, change in taste/smell sensation, blood clot in leg, depression. Early pancreas cancer's best chance for cure is surgery.
Pancreatic Cancer: Cancer of the pancreas are fast growing abnormal cells. These can be adenocarcinoma that can grow quickly, difficult to diagnose at an early stage & only sometimes can be removed with surgery. Endocrine cancers tend to be slower growing & may produce hormones & are surgically removed. Cystic cancers also may have better success with surgery. All of these can be difficult to diagnose & treat.
Abdominal organ. It is digestive organ: it secretes enzymes into the small bowel which break down food and help its absorption. It is also an endocrine organ: it produces hormones involved in sugar control and control of digestion. Insulin is one of these hormones. Diabetics either lack Insulin (type 1 diabetes) or have inadequate ...Read more
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