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Doctor insights on: Infliximab Infusion And Taking Methotrexate

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Methotrexate injections and pills didn't work for scleritis and was wondering if remicade (infliximab) is good medicine for the scletitis?

Methotrexate injections and pills didn't work for scleritis and was wondering if remicade (infliximab) is good medicine for the scletitis?

Resistant scleritis: Initial therapy always requires systemic nsaids, glucocorticoids, or other immunosuppressives (rituximab & cyclophosphamide). Cyclosporine & mycophenolate may also work. Azathioprine or mtx may be most beneficial for maintenance. Tnf Alpha inhibitors (eg infliximab) may be effective in resistant disease. Scleritis should ideally be managed by ophthalmologist+rheumatologist experts. ...Read more

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Methotrexate (Definition)

Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more


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Child on remicade (infliximab) and methotrexate what can I do to help her from getting sick when school starts back? Worried I can't keep her from sick kids

Child on remicade (infliximab) and methotrexate what can I do to help her from getting sick when school starts back? Worried I can't keep her from sick kids

Several things: Make sure your immunizations are up to date. Wash your hands frequently with soap and water after touching people or school things. You can carry a small bottle of hand sanitizer when soap not convenient. Keep your hands away from your face, eyes and head. Be careful not to get near those with colds, coughing and sneezing. Let the school nurse about your arthritis and medications. ...Read more

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Is remicade (infliximab) chemo if given at high does like methotrexate is? Nurse said remicade (infliximab) is in chemo family but not chemo. Unsure what she meant please expla

Is remicade (infliximab) chemo if given at high does like methotrexate is? Nurse said remicade (infliximab) is in chemo family but not chemo. Unsure what she meant please expla

No: Remicade (infliximab) is not chemotherapy...it is similar in that it is given IV. It is not a chemical structure and not a poison that is toxic to cell...it a biologic structure (an antibody) that blocks the overproduction of TNF, a messenger between immune cells. Hope this helps ...Read more

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I have been diagnosed with scleritis red and painful. The Remicade (infliximab) and Methotrexate took care of redness but pain still there.can I still have sclerit?

I have been diagnosed with scleritis red and painful. The Remicade (infliximab) and Methotrexate took care of redness but pain still there.can I still have sclerit?

Risk of damage: This can lead to damage of the sclera so you need to clarify with your ophthalmologist about surface damage. The pain is a clue to ongoing damage. ...Read more

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Doctor is offering me a choice of infliximab or methotrexate. Do I want either of these?

Doctor is offering me a choice of infliximab or methotrexate. Do I want either of these?

MTX 1st!: Go with mtx first . Preferably sc, rather than oral. Humira (adalimumab) works better when you are on mtx anyway! ...Read more

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For medium-active Crohn's disease, is remicade (infliximab) better off as the first line of treatment than methotrexate? Azoran has been ruled out.

See details: Often the combination of both is the most effective therapy. Often Methotrexate is tried first because it is easier to administer, is much less expensive and can be effective as a single agent. However, for severe disease i would opt for Remicade (infliximab) either alone or in combination as the first choice. ...Read more

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If a child on methotrexate and remicade (infliximab) gets a abcescss/MRSA do they need to be admitted or in some cases will oral antibiotics work?

If a child on methotrexate and remicade (infliximab) gets a abcescss/MRSA do they need to be admitted or in some cases will oral antibiotics work?

Depends. : Depends on the examining doctor who is taking care of his medications. As u may have been explained Remicade ( infliximab) may allow infections to become life threatening. If IV antibiotics are contemplated they can be administered at home with an indwelling peripheral vein catheter and nurse home visits. Sometimes just drainage of abscess is all that may be required. Close follow up is key. ...Read more

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Can Remicade (infliximab) and Methotrexate cause gastric ulcers?

Can Remicade (infliximab) and Methotrexate cause gastric ulcers?

Methotrexate usually: causes the GI upset, including nausea/vomiting, stomach ulceration and inflammation, abdominal discomfort, and diarrhea. If I were to to blame one of those, it would be Methotrexate! I would talk to your doctor more about this concern. ...Read more

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Can someone on methotrexate and remicade (infliximab) be admitted to hospital if they have staphylococcal folliculitis?

Can someone on methotrexate and remicade (infliximab) be admitted to hospital if they have staphylococcal folliculitis?

Folliculitis: Hi, if the problem is just Folliculitis and there is no systemic infection the best way to treat that person is as outpatient, because being in the hospital would put that person more at risk for more serious infection. ...Read more

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Infusion (Definition)

An infusion implies a substance administered via IV 2 a person, such as blood (transfusion), antibiotics and pain meds or other meds. Some can be ...Read more


Dr. Jeremy Adler
125 doctors shared insights

Infliximab (Definition)

Infliximab is an ...Read more