Doctor insights on:
Inflammatory Bowel Disease Diff Panel
Why is the p-anca test included in the inflammatory bowel disease panel that i just had done by labcorp?
Correlation: Low-level anti-neutrophil cytoplasmic antibodies of varying specificities, including anti-lysozyme and anti-myeloperoxidase, are often found in ulcerative colitis and sclerosing cholangitis. It's good to check as they support the diagnosis and may eventually be guides to treatment. ...Read more
The gastrointestinal tract starts at the mouth, travel down the tunnel (esophagus), which connects to the stomach, which then empties into the duodenum, jejunum, and ileum---the three parts of the small intestine (@25 feet). This empties into the colon or large intestine (about 5 feet), which then becomes the sigmoid colon, rectum and out the anus. So, every morsel eaten ...Read more
Depends: Inflammatory bowel disease generally refers to crohn's disease or ulcerative colitis. Both may give you diarrhea up to 10-20 movements per day, uc usually with blood mixed in, abdominal pain, weight loss, loss of energy and numeropus other associated co morbid conditions. If in doubt see either a colorectal surgeon or GI doctor. ...Read moreSee 2 more doctor answers
Medications: Variety of medications that will try to down regulate the inappropriate immune response found in ibd. Mesalamine (ie 5asa) products are a mainstay for uc and crohn's colitis. Other medications include immunosuppresant agents such as 6mp, immuran as well as biologic agents such as remicdae or humira. Steroids such as Prednisone are used in severe flares, but a not a long term option. ...Read moreSee 2 more doctor answers
Many options: 1. 5-asa medications (sulfasalazine, asacol, pentasa) may work for mild ulcerative colitis (uc), but not crohn's disease. 2. Steroids work, but are only useful for short course because of side effects. 3. Azathioprine (imuran), 6-mp, Methotrexate are often effective, and reduce the need for steroids. 4. Remicade, Humira are often effective for crohn's, sometimes for uc. 5. Surgery if needed. ...Read moreSee 1 more doctor answer
Cure for IBD?: Ulcerative colitis involves inflammation of the colonic mucosal surface, so colectomy (removal of the colon) is curative for it. Crohn's disease however is a transmural (full-thickness) inflammation of any part of the GI tract (from mouth to anus). Crohn's is not curable, but it is controllable with medications (see my previous healthtap answer regarding "step up" versus "top down" treatments. ...Read moreSee 1 more doctor answer
Cramps diarrhea: Symptoms vary from patient to patient, but most have some sort of abdominal pain - usiually cramping and loose, frequent bowel movements. Sometimes fever, sometimes blood in the stool, frequently weight loss if the symptoms are bad enough. See your doctor because many of these symptoms are nonspecific. ...Read moreSee 1 more doctor answer
With flares, but...: Ulcerative colitis involves inflammation of the colonic mucosal surface, so colectomy (removal of the colon) is curative for it. Crohn's disease however is a transmural (full-thickness) inflammation of any part of the GI tract (from mouth to anus). Crohn's is not curable, but it is controllable with medications (see my previous healthtap answer regarding "step up" versus "top down" treatments. ...Read moreSee 2 more doctor answers
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