Doctor insights on:
Infections That Disqualify Bone Marrow Donation
Saves lives: Pros far outweigh the cons. You can save lives and provide an amazing gift to a very sick person by this selfless act of kindness. Minor chance of infection, and can be a little painful. ...Read more
Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately ...Read more
Get familiar: You can gather all the information and get educated. Internet has plenty of information or you can go to any blood bank in a hospital and obtain literature about the procedure. There is a national marrow donor program (nmdp) which provides all the info you may need. ...Read more
Not clear?: Please be more exact in asking what you want to know. ...Read more
Stem cell collection: Some times stem cells for transplant can be collected from an IV in your arm. This process involves a medication, g-csf, which increases the stem cells. This medication can cause flu-like symptoms and bone pain. Then the cells are taken, similar to giving blood or platelets. ...Read moreSee 1 more doctor answer
No.: If you volunteer for the bone marrow registry you agree to donate for free. It is illegal to charge for transplanted organs or tissues, other than the costs involved in collecting the tissue. You can be paid by a company that wants marrow for a non-transplant reason like research or other commercial purpose. ...Read more
Like giving blood: BM donors are given a drug to make bone marrow stem cells move into the bloodstream. That can cause bone aches for a few days. The cells are collected through a needle inserted into a vein. That site can be sore and you might be a little tired after donating. There are no long term side effects. ...Read more
A little.: The actually collection of blood stem cells uses a machine connected to the donor through a needle in a vein, and is much like donated blood and not painful. To get the stem cells into the blood stream, donors are given neupogen, a drug to force stem cells into the blood. That drug can cause bone aching for a few days. It feels much like body aching when you have the flu, if it occurs. ...Read more
How does one differentiate between infection n malignancy in the bone marrow plasma cell percentage?
Monoclonal or not: Malignant plasma cells are monoclonal in that they are copies of each other and produce the same antibody. This antibody can be identified in urine or blood tests in malignancy. Increased plasma cells due to infection are polyclonal (not copies of each other) and produce non-identical antibodies. ...Read more
Yes.: Work up of possible infection of bone, called osteomyelitis, can be done by looking at the bone marrow under the microscope to see if bacteria is there, placing bits of the marrow on agar plates to see if any bacteria can be cultured (grown), getting plain x-rays, getting a bone scan, and checking the blood for infection including doing asedimentation rate and c-reactive protein test. ...Read moreSee 1 more doctor answer
Is it possible to get an infection at the site where a bone marrow biopsy was done 6 weeks ago? Would infection be possible so long after procedure
Yes it is: You should follow up with the doctor who did the biopsy. Have wound cultured get full blood work check including IgG levels. Also b12 and folic acid deficiency can cause elevated RDW. With low vitamin D you may also have a component of leaky gut syndrome. Discuss with your doctor the Gapsdiet. Com if biopsy was done in hospital make sure they check for MRSA ...Read more
They can: But usually it would be taken from the hip. ...Read more
Your WBC increases with polycythemia because the bone marrow is so hyperactive. So why are you more at-risk for infections?
Wrong cells: In polycythemia [ increased red cells] can ocur for a number of reasons. You are at risk for complications of whatever disorder caused the increase in RBCs. Conditions such as, pulmonary fibrosis, at times COPD a connection between the great vessels of the body, a vascular shunt, some drug reactions, and true polycythemia in which the bone-marrow makes too many RBCs. ...Read more
Adult male, bone marrow biopsy show Erythroid hyperplasia RBC borderline on high side, thrombocytopenia fluctuate, Splenomegaly, negative for infections.
CBC Results: If you can send us the complete blood count (CBC) report which includes Hb, WBC, Platelet counts done from 2 different dates, we can tell you if there is anything serious or how to manage your concerns. WE need to know the number of platelets (Count). RBC numbers are not useful...instead we use hemoglobin as a better test to reflect any problems with RBCs. ...Read more
I'm waiting to be a bone marrow donor, but have enlarged lymph nodes, will this hinder my, donation?
Evaluation: You should be evaluated for cause of large lymph nodes and if is benign you are ok for donation. ...Read more
Bone marrow harvest: A standard bone marrow biopsy test involves 1 or 2 needle insertions into the iliac crest bone. Depending on the size of the recipient and how many cells are needed it can be from approximately 20-50 needle insertions on each side for a bone marrow harvest/donation. ...Read more
To make diagnosis: And to judge response/remission.Get a more detailed answer ›
Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more
Infections are invasions of some other organism (fungus, bacteria, parasite) or viruses into places where they do not belong. For instance, we have normal gut bacteria that live within us without causing problems; however, when those penetrate the bowel wall and enter the bloodstream, ...Read more
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