Top
10
Doctor insights on: Indirect Antiglobulin Test

Share
1

1
Had a Rhogam in injection in January. In March (9 weeks later) I had INDIRECT ANTIGLOBULIN TEST and tested positive. Is this because of the rhogam?

Had a Rhogam in injection in January. In March  (9 weeks later) I had INDIRECT ANTIGLOBULIN TEST and tested positive.  Is this because of the rhogam?

Likely: The half life of immunogloblin G is about 4 weeks, therefore you are likely to have residual antibody from the Rhogam injection at 7 weeks after the injection. Your doctor may wish to retest in about 6 months. ...Read more

2

2
I am RH negative, pregnant for the first time and tested positive to INDIRECT ANTIGLOBULIN TEST. How will this affect my 1st pregnancy?

I am RH negative, pregnant for the first time and tested positive to  INDIRECT ANTIGLOBULIN TEST.  How will this affect my 1st pregnancy?

Need more info: Did you ever receive blood transfusion? Could you have had a miscarriage? If by positive antiglobulin test you mean that you have antibody to Rh, that is distinctly uncommon in first pregnancy. However, it does not preclude you from having a successful pregnancy and a healthy baby. You need to see your obstetrician and be compliant with all the suggestions for follow-up and tests. ...Read more

3

3
I am rh- and my boy friend is rh- so will my babys indirect Coombs test came back positive?

I am rh- and my boy friend is rh- so will my babys indirect Coombs test came back positive?

Baby is also Rh- : Your baby will also be rh-. Because rh- is recessive to rh+ you and your boyfriend both have two rh- genes. Your haplotype is rh-/rh- and your phenotype rh- and so is his. You and he can only give rh- genes to your babies. All of your babies with this father will be rh-/rh-. Don't sweat it. ...Read more

4

4
What are the differences between direct Coombs test and indirect Coombs test?

What are the differences between direct Coombs test and indirect Coombs test?

Both test Ag-Ab rxns: Direct Coombs will test for the reaction using the patient’s RBCs, if there is a reaction, then the direct test is positive, used to test for autoimmune hemolytic anemia. Indirect Coombs test uses the patient’s serum (not rbcs) which is added to rbcs that are known to have a certain antigenicity, positive in cases of hemolytic diseases of the newborn, mother's serum against baby's RBCs, ...Read more

5

5
What is the difference between the direct Coombs test and indirect Coombs test?

What is the difference between the direct Coombs test and indirect Coombs test?

Bound vs unbound ABs: Direct coombs' test is used to detect antibodies that are already bound to the surface of red blood cells. Many diseases and drugs (quinidine, methyldopa, and procainamide) can lead to production of these antibodies indirect coombs' test looks for unbound circulating antibodies against a series of standardized red blood cells. The indirect coombs' test is only rarely used to diagnose a condition. ...Read more

6

6
Why can't you donate plasma with an abnormal indirect Coombs test result?

Why can't you donate plasma with an abnormal indirect Coombs test result?

Antibody to red cell: A person with positive indirect coombs test has antibodies to red cells. If such plasma is transfused into a person, s/he could suffer loss of her/his own red cells. ...Read more

7

7
I am b - hubby is o +. I am not pregnant but before pregnancy can I get the indirect Coombs test done to check if my blood is sensitized?

I am b - hubby is o +. I am not pregnant but before pregnancy can I get the indirect Coombs test done to check if my blood is sensitized?

Ask OB/Gyn: Easier and safer to get Rhogam shot to provide passive protection to fetus, if are or might become sensitized to (+) due to any peri-placental sharing. ...Read more

9

9
How can I test my pain tolerance?

How can I test my pain tolerance?

Any thing that you: Do to your body that causes extreme pain is likely to damage your body. There are really no reasons to need to have an exact knowledge of what your pain threshold is. That is also a very subjective thing to try to rate. Enough painful things occur in life without people deliberately inflicting pain upon themselves. ...Read more