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Indirect Antiglobulin Test
Had a Rhogam in injection in January. In March (9 weeks later) I had INDIRECT ANTIGLOBULIN TEST and tested positive. Is this because of the rhogam?
I am RH negative, pregnant for the first time and tested positive to INDIRECT ANTIGLOBULIN TEST. How will this affect my 1st pregnancy?
Need more info: Did you ever receive blood transfusion? Could you have had a miscarriage? If by positive antiglobulin test you mean that you have antibody to Rh, that is distinctly uncommon in first pregnancy. However, it does not preclude you from having a successful pregnancy and a healthy baby. You need to see your obstetrician and be compliant with all the suggestions for follow-up and tests. ...Read more
Baby is also Rh- : Your baby will also be rh-. Because rh- is recessive to rh+ you and your boyfriend both have two rh- genes. Your haplotype is rh-/rh- and your phenotype rh- and so is his. You and he can only give rh- genes to your babies. All of your babies with this father will be rh-/rh-. Don't sweat it. ...Read more
Both test Ag-Ab rxns: Direct Coombs will test for the reaction using the patient’s RBCs, if there is a reaction, then the direct test is positive, used to test for autoimmune hemolytic anemia. Indirect Coombs test uses the patient’s serum (not rbcs) which is added to rbcs that are known to have a certain antigenicity, positive in cases of hemolytic diseases of the newborn, mother's serum against baby's RBCs, ...Read more
Bound vs unbound ABs: Direct coombs' test is used to detect antibodies that are already bound to the surface of red blood cells. Many diseases and drugs (quinidine, methyldopa, and procainamide) can lead to production of these antibodies indirect coombs' test looks for unbound circulating antibodies against a series of standardized red blood cells. The indirect coombs' test is only rarely used to diagnose a condition. ...Read more
I am b - hubby is o +. I am not pregnant but before pregnancy can I get the indirect Coombs test done to check if my blood is sensitized?
Any thing that you: Do to your body that causes extreme pain is likely to damage your body. There are really no reasons to need to have an exact knowledge of what your pain threshold is. That is also a very subjective thing to try to rate. Enough painful things occur in life without people deliberately inflicting pain upon themselves. ...Read more
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