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Doctor insights on: Increased Pigmentation On Knuckles

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Can subcutaneous nodules(around 1 cm) on lower legs that slightly itch wid little swelling and blackening(purplish)of skin on legs be signs of cancer?

Can subcutaneous nodules(around 1 cm) on lower legs that slightly itch wid little swelling and blackening(purplish)of skin on legs be signs of cancer?

Let's biopsy: I'm actually more concerned about a cryoglobulin or leukocytoclastic vasculitis. If you have been offered a biopsy, by all means go for it. This does not sound like erythema nodosum, but i've learned not to try to second-guess a rash / skin eruption without seeing it. ...Read more

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Can lupus cause loss of pigmentation on face?

Can lupus cause loss of pigmentation on face?

Yes: But mostly raised demarcated reddish lesions, usually sun sensitive. There are other types of rashes, some may scar. Vitiligo or loss of pigment may happen on its own due to antibodies to melanin. ...Read more

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Blood pooling, both feet - outer along talus/tarsals. Edema right foot/hand. Knuckles red or bluish, feet/hands hot/splotchy, big veins w/ activity?

Blood pooling, both feet - outer along talus/tarsals. Edema right foot/hand.  Knuckles red or bluish, feet/hands hot/splotchy, big veins w/ activity?

May be acrocyanosis: Some of these symptoms match acrocyanosis, which is a physiologic way that blood can cause pooling. The edema is not related . Cannot say why your hands are splotchy . Your evaluation may help clarify your medical situation. ...Read more

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Could periodic rapid thickening (then splitting and peeling) of skin on tips of all fingers and toes combined with rust colored pits on finger pads indicate an autoimmune problem?

Could periodic rapid thickening (then splitting and peeling) of skin on tips of all fingers and toes combined with rust colored pits on finger pads indicate an autoimmune problem?

Its possible: Rough, thick skin on the finger tips with cracks and discoloration can be related to repeated exposure to chemicals/dry environment. This can also be seen is polymyositis and dermatomyositis which are autoimmune diseases involving primarily the muscles and skin respectively. ...Read more

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Pale red dots on cheek. 18 years old. Always wore sunscreen. Never had acne. Hyper pigmentation? Underlying freckles? Uneven skin tone? Narrow down?

Pale red dots on cheek. 18 years old. Always wore sunscreen. Never had acne. Hyper pigmentation? Underlying freckles? Uneven skin tone? Narrow down?

Sorry...: But is sounds like you have narrowed down your options about as much as anyone can without actually seeing the lesions that you are referring to. Instead of narrowing it down, I could add other possibilities but that would be fruitless. If you are interested in an actual answer you will need to see a physician (primary care or dermatologist). Take care. ...Read more