Doctor insights on:
Inclusion Body Myositis Prognosis
Myopathy type: Ibm is atype of inflammatory myositis. It tends to affect people older than 50. People with ibm often have weakness of their upper and lower arms and legs. Sometimes the muscles look smaller known as atrophy. Unfortunately there are no treatments that are proven to help. However, patients are sometimes tried on a short course of steroids, ivig, etc. Phys therapy is extremely important. ...Read moreSee 1 more doctor answer
A wide spectrum Pts.: This is an inflammatory muscle disease, with slowly progressive weakness and wasting of both distal and proximal muscles, most notably of the arms and legs. Because this randomly affects different people in different ways and at different rates, there is no "textbook case." there are two kinds, sporadic and hereditary. The hereditary case does not have inflammation and is thus not myositis. ...Read more
With a stick maybe?: No definitive treatment has proved effective for the sporadic form of the disease. A militaristic tough-as-nails let's-hard-nose-this-one-out how-to-beat-it when-the-going-gets-tough-the-tough-get-going attitude toward this disease will only cause greater feelings of failure and frustration down the line. Most proactive thing is to try to get into a clinical trial, see clinicaltrials.gov. ...Read moreSee 1 more doctor answer
Different diseases: Both are muscle diseases that are difficult to treat, polymyositis tending to affect shoulders and hips, inclusion body mysoitis the forearms. Polymyositis is the more treatable, but the more likely to become very serious, we know something of its cause unlike inclusion body myositis. Under the microscope they look different. Both are difficult and i wish you good luck and courage. ...Read more
Is there research into any genetic, autoimmune or other condition that links nerve sheath disorders (tarlov cysts, nerve sheath tumor) with autoimmune hypophysitis targeting acth cells? Ctla-4 gene?
Immune modulation: Ipilimumab is a drug used to treat melanoma. It targets ctla-4, which is a t cell receptor that downregulates part of the immune system. A side effect has been described: autoimmune hypophysitis (inflammation of the pituitary) which can knock out many hormones, including acth. There are a few articles on this. Torino et al, oncologist 2012; 17:525. ...Read more
Ck emyograph biopsy: Ten fold increase creatine kinase enzyme,electromyography, muscle biopsy sent to neuropathologists, or human leucocyte gene assays using gene sequencing or similar tests will Narrow this down to sporadic type but this is a disease that begs more discoveries. Of course your doc needs to determine if your symptoms are those of IBM. ...Read moreSee 1 more doctor answer
Inflammation leftface salivary glands & lymph nodes-no bacterial viralfungal & immune-spinal tap high protein-hx metastatic breast cancer w bone mets?
Possible mets: There is a type of breast cancer called lobular breast cancer that tends to metastasize to lymph nodes and salivary glands. Her2 positive breast cancer can also behave this way. I think your swollen salivary glands and lymph nodes are due to metastatic breast cancer. Make sure your doctor considers this possibility. ...Read moreSee 1 more doctor answer
May i know the simple explanation for this diagnosis: (post auricular area), excision biopsy: cellular spindle cell lesion favor nodular fascitis?
Get 2nd opinion: A pathologist who trained at one of my institutions self-diagnosed a sarcoma and had his arm amputated, only to discover later it was nodular fasciitis, which is very benign. I was trained by some of the great pathologists and even they said they'd never call nodular fasciitis without a second pathologist agreeing. I'd suggest showing 3-4 of us pathologists. Good luck. ...Read more
Muscle Biopsy Results Meaning? rare chronic inflammatory
cells, composed of CD3/CD8 positive T-lymphocytes and CD68 positive macrophages.
All lab test need ..: With data we need clinical context. That is why you are having trouble. There is not enough information to provide an interpretation. ...Read more
M77 , biopsy of vastus laterilus muscle says "secondary neurogenic atrophy with super imposed inflmatory myopathy" which disease this may be?thanks
Your doctor needs: to findout if you have any cause for your neuropathy. This can be from many causes - usually diabetes or alcohol or other drugs are the cause. You need to go over with your doctor what possible things in your life are responsible for it. The secondary inflammation suggests you have a compromised immune system or slightly weakened one. People usually do not get inflammation of the muscle. ...Read more
The tumor is composed of glands lined by malignant epithelial cells.The tumor is overlain by ulcerated , acanthotic epid . Please what does this means?
Duscuss with doctor: You have to have a personal discussion with your doctor concerning these findings. If you don't understand, ask questons until you do. If you want a second opinion, request it. ...Read more
Does metastatic cheek 1.5cm lymph node & almost completely occupied by a tumor proliferation without extracapsular extension need radiotherapy?
Maybe: Not always - need to sample additional and if carcinoma still present would rec XRT ; can do a scan to see if any residual tumor. ...Read more
Rx of myositis ossificans: Treatment of myositis ossificans involves the RICE principle of rest, ice, compression and elevation and non-painful, passive stretching and strengthening routine. I suggest you have an exam by a sports medicine specialist who can assist you with proper diagnosis and treatment for this condition. Best of luck with your health! ...Read more
What is life expectancy of small cell neuroendrocrine carcinoma that metastizied to the brain (35 tumors) and spinal fluid (3 tumors)?
Metastatic brain ca: Poor prognosis. 6-8 months or less especially if more than one. ...Read more
- Talk to a doctor live online for free
- Inclusion body myositis dysphagia
- Hereditary inclusion body myositis
- Treatment of inclusion body myositis
- Ask a doctor a question free online
- Inclusion body myositis support groups
- Inclusion body myositis treatment options
- Diet for inclusion body myositis
- Leg exercises for inclusion body myositis
- Talk to a orthopedic surgeon online for free