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Doctor insights on: Inclusion Body Myositis Prognosis

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What is inclusion body myositis?

What is inclusion body myositis?

Myopathy type: Ibm is atype of inflammatory myositis. It tends to affect people older than 50. People with ibm often have weakness of their upper and lower arms and legs. Sometimes the muscles look smaller known as atrophy. Unfortunately there are no treatments that are proven to help. However, patients are sometimes tried on a short course of steroids, ivig, etc. Phys therapy is extremely important. ...Read more

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Prognosis (Definition)

The prognosis is the predicted outcome or "forecast" for a disease or process. It is only an estimate but is likely based on past experience or data taking into account the individual's overall health status. It may suggest progression of disease ...Read more


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What is inclusion body myositis (ibm)?

What is  inclusion body myositis (ibm)?

Genetic disorder: Ibm is a genetic disease in the group of diseases called inflammatory myopathies. It is progressive and leads to muscle weakness and wasting away of muscle. There is no cure but there are therapies that can help with symptoms. ...Read more

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What are dermatomyositis, polymyositis and inclusion body myositis?

Separate myosotis : Each is a specific type of inflammatory muscle disease. We call this myositis because the muscles can show information. When you have this you need an extensive evaluation looking for other associated issues. Therapy will be different for each of these. ...Read more

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Who has inclusion body myositis?

A wide spectrum Pts.: This is an inflammatory muscle disease, with slowly progressive weakness and wasting of both distal and proximal muscles, most notably of the arms and legs. Because this randomly affects different people in different ways and at different rates, there is no "textbook case." there are two kinds, sporadic and hereditary. The hereditary case does not have inflammation and is thus not myositis. ...Read more

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How to beat inclusion body myositis?

With a stick maybe?: No definitive treatment has proved effective for the sporadic form of the disease. A militaristic tough-as-nails let's-hard-nose-this-one-out how-to-beat-it when-the-going-gets-tough-the-tough-get-going attitude toward this disease will only cause greater feelings of failure and frustration down the line. Most proactive thing is to try to get into a clinical trial, see clinicaltrials.gov. ...Read more

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How does 'inclusion body myositis' affect a person's lifestyle?

Weakness.: Weakness is the main symptom of inclusion body myositis. This is usually most severe in the distal upper extremities (hands) and proximal lower extremities (hips). Physical therapy and regular physical activity are important to optimize function. ...Read more

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What defining difference exists between polymyositis and inclusion body myositis?

What defining difference exists between polymyositis and inclusion body myositis?

Different diseases: Both are muscle diseases that are difficult to treat, polymyositis tending to affect shoulders and hips, inclusion body mysoitis the forearms. Polymyositis is the more treatable, but the more likely to become very serious, we know something of its cause unlike inclusion body myositis. Under the microscope they look different. Both are difficult and i wish you good luck and courage. ...Read more

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Is there research into any genetic, autoimmune or other condition that links nerve sheath disorders (tarlov cysts, nerve sheath tumor) with autoimmune hypophysitis targeting acth cells? Ctla-4 gene?

Is there research into any genetic, autoimmune or other condition that links nerve sheath disorders (tarlov cysts, nerve sheath tumor) with autoimmune hypophysitis targeting acth cells? Ctla-4 gene?

Immune modulation: Ipilimumab is a drug used to treat melanoma. It targets ctla-4, which is a t cell receptor that downregulates part of the immune system. A side effect has been described: autoimmune hypophysitis (inflammation of the pituitary) which can knock out many hormones, including acth. There are a few articles on this. Torino et al, oncologist 2012; 17:525. ...Read more

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What are the diagnostic tests for inclusion body myositis?

Ck emyograph biopsy: Ten fold increase creatine kinase enzyme,electromyography, muscle biopsy sent to neuropathologists, or human leucocyte gene assays using gene sequencing or similar tests will Narrow this down to sporadic type but this is a disease that begs more discoveries. Of course your doc needs to determine if your symptoms are those of IBM. ...Read more

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Inflammation leftface salivary glands & lymph nodes-no bacterial viralfungal & immune-spinal tap high protein-hx metastatic breast cancer w bone mets?

Inflammation leftface salivary glands & lymph nodes-no bacterial viralfungal & immune-spinal tap high protein-hx metastatic breast cancer w bone mets?

Possible mets: There is a type of breast cancer called lobular breast cancer that tends to metastasize to lymph nodes and salivary glands. Her2 positive breast cancer can also behave this way. I think your swollen salivary glands and lymph nodes are due to metastatic breast cancer. Make sure your doctor considers this possibility. ...Read more

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May i know the simple explanation for this diagnosis: (post auricular area), excision biopsy: cellular spindle cell lesion favor nodular fascitis?

May i know the simple explanation for this diagnosis: (post auricular area), excision biopsy: cellular spindle cell lesion favor nodular fascitis?

Get 2nd opinion: A pathologist who trained at one of my institutions self-diagnosed a sarcoma and had his arm amputated, only to discover later it was nodular fasciitis, which is very benign. I was trained by some of the great pathologists and even they said they'd never call nodular fasciitis without a second pathologist agreeing. I'd suggest showing 3-4 of us pathologists. Good luck. ...Read more

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Muscle Biopsy Results Meaning? rare chronic inflammatory cells, composed of CD3/CD8 positive T-lymphocytes and CD68 positive macrophages.

Muscle Biopsy Results Meaning? rare chronic inflammatory
cells, composed of CD3/CD8 positive T-lymphocytes and CD68 positive macrophages.

All lab test need ..: With data we need clinical context. That is why you are having trouble. There is not enough information to provide an interpretation. ...Read more

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M77 , biopsy of vastus laterilus muscle says "secondary neurogenic atrophy with super imposed inflmatory myopathy" which disease this may be?thanks

M77 , biopsy of vastus laterilus muscle says "secondary neurogenic atrophy with super imposed inflmatory myopathy" which disease this may be?thanks

Your doctor needs: to findout if you have any cause for your neuropathy. This can be from many causes - usually diabetes or alcohol or other drugs are the cause. You need to go over with your doctor what possible things in your life are responsible for it. The secondary inflammation suggests you have a compromised immune system or slightly weakened one. People usually do not get inflammation of the muscle. ...Read more

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The tumor is composed of glands lined by malignant epithelial cells.The tumor is overlain by ulcerated , acanthotic epid . Please what does this means?

The tumor is composed of glands lined by malignant epithelial cells.The tumor is overlain by ulcerated , acanthotic epid . Please what does this means?

Duscuss with doctor: You have to have a personal discussion with your doctor concerning these findings. If you don't understand, ask questons until you do. If you want a second opinion, request it. ...Read more

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How is myositis ossifans cured?

Rx of myositis ossificans: Treatment of myositis ossificans involves the RICE principle of rest, ice, compression and elevation and non-painful, passive stretching and strengthening routine. I suggest you have an exam by a sports medicine specialist who can assist you with proper diagnosis and treatment for this condition. Best of luck with your health! ...Read more

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What is an epitheloid malignant peripheral nerve sheath tumor?

What is an epitheloid malignant peripheral nerve sheath tumor?

Malignant Periph. N.: Also called Malignant Schwannoma or Neurosarcoma, is a connective tissue cancer of connective tissue surrounding the nerves. Exists in 50% of ones with Neurofibromatosis. Treatment is wide resection by surgery, Chemotherapy & Radiotherapy. ...Read more

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Is myositis ossificans a rare condition?

How rare?: What frequency would you consider rare? It is a well-known condition, usually occurring as a result of trauma. ...Read more

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Is benign adnexal skin tumor compatible with eccrine poroma cancerous?

Is benign adnexal skin tumor compatible with eccrine poroma cancerous?

Benign& malignant: Skin adenexal tumors (sat ) tumors of sweat glands, ( eccrine& apocrine glands ) hair follicles , are both benign and malignant . Malignant which is lethal if excision is not done early. Eccrine porocarcinoma is malignant variety and it is not a benign tumor. ...Read more

Dr. Charles Glueck
693 doctors shared insights

Myositis (Definition)

Inflammation of the muscles that you use to move the body. Symptoms of myositis may include fatigue after walking or standing, tripping or falling, ...Read more