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Doctor insights on: Inapsine Inotrope

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When is inapsine (droperidol) used?

When is inapsine (droperidol) used?

Refractory PONV: Inapsine (droperidol) is also known as Droperidol which was extensively used in 90s then it had fda warning for qt prolongation leading to cardiac arrest so we have not been using it unless patients have resistant postoperative nausea and vomiting. ...Read more

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Inapsine (Definition)

Droperidol is an inotrope which is a kind of heart ...Read more


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Antidote for beta blocker overdose?

Antidote for beta blocker overdose?

Answer: If severe or symptomatic, intravenous pressers (drugs that mimic adrenaline) and/or temporary pacing is needed. This is not to be tried at home kids! if not severe and patient young/healthy, might only need close monitoring and IV fluids in icu. I hope this person is in a hospital! ...Read more

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Do selective adeno-adenergic blockers (prazosin, terazosin, doxazosin, trimazosin) protect  from acute cocaine-induced vasoconstrictive damage?

Do selective adeno-adenergic blockers (prazosin, terazosin, doxazosin, trimazosin) protect  from acute cocaine-induced vasoconstrictive damage?

Some: Cocaine causes it's effect by preventing the reuptake of monamine (epinephrine, etc) and causes these neurotransmitters to continue exciting the a1 receptor. The meds listed block alpha-1 receptors, so theoretically will blunt the effects of Cocaine on some vessels, but focus mostly (esp. Tamsulosin) on a specific sub-type (alpha-1a) that is mostly in the bladder, not in the vessels. ...Read more

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Why is dobutamine given intravenously?

Why is dobutamine given intravenously?

No other form: Presently, there is no other form of Dobutamine on the market. Generally, when Dobutamine is used, one is seeking immediate action of the drug, if the drug was administered through just about any other route, it would take longer to act and the delay in action is not desirable. This of course excludes CHF patients on chronic Dobutamine pump, my first sentence is directed at them. ...Read more

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Glutamine excitatory or inhbitory?

Glutamine excitatory or inhbitory?

Both, indirectly: Glutamine is a major precursor of glutamate, the most potent excitatory neurotransmitter, & of gaba (gamma-aminobutyric acid), the most potent inhibitory neurotransmitter in mammalian brains. ...Read more

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Beta blocker overdose fatal?

Beta blocker overdose fatal?

Can be, not usually: Beta blockers can slow the heart, decrease blood pressure, cause abnormal heart rhythms (even fatal ones), cause bronchospasm (asthma/wheezing), heart failure, mental status changes, rash, allergic reactions. May require aggressive medical rx, especially if taken with other meds. ...Read more

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Why is digoxin contraindicated in ventricular tachycardias?

Why is digoxin contraindicated in ventricular tachycardias?

Ventricular tachycar: Ventricular tachycardia is a dangerous cardiac rhythm and one of the abnormal rhythms caused by digoxin toxicity. Digoxin could cause worsening of VT or conversion to vf. ...Read more

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Why were erythropoiesis-stimulating agents banned?

From sports: Because using them is cheating. Many are useful in clinical medicine. ...Read more

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Is histamine excitatory or inhibitory?

Is histamine excitatory or inhibitory?

Excitatory: Histamine is actually classified as an excitatory neurotransmitter in the brain responsible for the sleep wake cycle. Too much of it can keep you awake. That is why it is used in many commercial sleep aides seen with the letters "pm" attached to some kind of pain killer. A common side-effect of a histamine blocker like Diphenhydramine (benadryl) is drowsiness. ...Read more

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Is stanozolol a beta receptor antagonist?

Is stanozolol a beta receptor antagonist?

Stanozolol: Stanozolol is a synthetic anabolic steroid derived from testosterone. It is banned from use in athletes but has a role in some medical conditions. Please look up stanozolol in Wikipedia on the internet. ...Read more

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Benztropine mesylate uses?

Benztropine mesylate uses?

There are a few uses: Benztropine is an anticholinergic drug used to reduce the side effects of antipsychotic treatment, such as pseudoparkinsonism and dystonia. It is also a second-line drug for the treatment of parkinson's disease. It improves tremor but not rigidity and bradykinesia. It is also sometimes used for dystonia, a rare disorder that causes abnormal muscle contraction. ...Read more

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Is ketamine a viable anti-depressant drug therapy? Vfhjr.

Is ketamine a viable anti-depressant drug therapy?

Vfhjr.

Ketamine: Ketamine offers very interesting possibilities for depressed patients who don't respond to standard therapies. It does induce dissociation and sometimes hallucinations, but in some there's an antidepressant effect that lasts for several hours/days after those are gone. Some drawbacks: can be liver damage; it must be given IV in a controlled setting; effects may wear off. All is being studied. ...Read more

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Why is adrenaline contraindicated in hypotensive shock?

Why is adrenaline contraindicated in hypotensive shock?

It's not: But typically you want to volume resuscitate prior to using a pressor like Epinephrine or norepinephrine because that typically fixes the problem. ...Read more

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Can succinylcholine drugs (nicotinic depolarizing neuromuscular blocker) decrease intraocular pressure? Any answers appreciated!

Can succinylcholine drugs (nicotinic depolarizing neuromuscular blocker) decrease intraocular pressure? Any answers appreciated!

No.: Succinylcholine actually causes an increase in intraocular pressure for about 10 minutes after administration. Classic teaching was not to use succ in people with open globe injuries. There are situations, though, where using succ with other agents that lower IOP is preferred because it makes intubation more smooth, avoiding hypertension and airway reactivity that is worse for the situation anyway ...Read more

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Will Narcan (naloxone) reverse an opiate overdose once cardiac arrest has occurred?

Will Narcan (naloxone) reverse an opiate overdose once cardiac arrest has occurred?

Not completely: Narcan (naloxone) can reverse a narcotic overdose to a point. If someone takes a narcotic overdose, and it is enough to stop breathing, the lack of oxygen and rise in carbon dioxide can cause the heart to stop ( cardiac arrest) at that point simply reversing the effect of the narcotic that started the process is not enough, one take additional measures to restore a pulse and resuscitate the patient. ...Read more

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What is nipride (nitroprusside) drip?

What is nipride (nitroprusside) drip?

Nitroprusside: Nipride is nitroprusside a vasodilator (means open up blood vessels) which is used to lower blood pressure. It is given intravenously(through the veins) and is usually used in severe hypertensive(high blood pressure) situations. It needs to be closely monitored as it can at times lower blood pressure too much. ...Read more

Dr. Steven Smith
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Droperidol (Definition)

Droperidol is an inotrope which is a kind of heart ...Read more