Doctor insights on:
Imuran Side Effects
Bone marrow toxicity: Imuran (azathioprine) is a non specific immunosuppressive drug that works by blocking the proliferation of activated immune white blood cells (lymphocytes, monocytes, granulocytes, etc.). It can cause too much bone marrow suppression, liver toxicity, hair loss, nausea, vomiting, etc. You should discuss any side effects with your doctor. ...Read moreSee 1 more doctor answer
Disease may flare: Imuran (azathioprine) is a non specific immunosuppressive drug used in several autoimmune diseases (i.e. Inflammatory bowel disease) and transplant rejection. It usually suppresses the formation of white blood cells. If suddenly stopped the reason it was prescribed may suddenly flare. You should discuss changing the dose with your doctor. ...Read more
Mostly none: If you're taking Imuran at the doses used to teat ibd, most have no side effects. Few are allergic and develop pancreatitis. The biggest issue is to monitor blood counts to make sure WBC doesn't go too low, which can lead to serious infections. Occasionally liver enzymes can go up, which is reversible. Very rarely associated with malignancy. You should have tpmt checked before starting. ...Read more
Immune suppression: Imuran is a medication which suppresses your immune system. This can lead to an increased risk of infections such as viruses and colds. Other side effects are less common, such as nausea and vomiting, suppression of bone marrow function (especially white and red blood cells), pancreas inflammation and liver dysfunction. Long term use may be associated with certain types of cancers (lymphoma, skin) ...Read more
I have been on imuran 50 mg for about 2 months, how long do people usually stay on this medication, because it has many side effects and I am worried?
Crohn's dosease: Depends on the relief of symptoms called remission. The remission time is different in person to person. Looks like you have flare or relapse because you are taking other meds as well. Your doctor would evaluate the status of crohn's disease time to time and adjust the treatment accordingly. ...Read more
It is dose dependent: The toxicity depends how much you are taking and how long.... . It also depends what other med you are on i.e. Med for gout.....if you are with antigout....bone marrow suppression can be a serious condition. .......infection,liver function alteration,cancer etc.....low dose should not be a problem and are given for many conditions and patient can be on for long time with regular follow ups ...Read more
If methotrexate injworked great at controlling my symptoms but gave me GI issues, is it likely that imuran tablets would give me GI side effects too?
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