Doctor insights on:
What can cause mild elevation of ALT 51 and range up to 33 with a normal AST .. and can using medication(imuran,asprin,hydroquin for 3 days cause that?
I have been on imuran (azathioprine) 50 mg for about 2 months, how long do people usually stay on this medication, because it has many side effects and I am worried?
Crohn's dosease: Depends on the relief of symptoms called remission. The remission time is different in person to person. Looks like you have flare or relapse because you are taking other meds as well. Your doctor would evaluate the status of crohn's disease time to time and adjust the treatment accordingly. ...Read more
Dx of pancreatic insufficiency. On imuran (azathioprine) and prednisolone(for aied, history of uc), is there any point getting igg4 levels done if on these medication?
Daughter with Crohn's has been getting a sore throat for the last year.On imuran and pentasa. Could it be from her medication? Recently started Nexium (esomeprazole)
Imuran (azathioprine): "Azathioprine (Imuran (azathioprine)) is a drug used to treat swelling and pain in arthritis. The most common diseases treated with Imuran (azathioprine) are dermatomyositis, systemic lupus erythematosus and vasculitis. It belongs to a class of medications called disease-modifying antirheumatic drugs (DMARDs) or immunosuppressants. This class of medicines can decrease joint damage and disability" ...Read more
Reduce WBC: Azathioprin (imuran) lowers the white blood cell (WBC) count. Wbcs are part of the immune system that fight infection, but also cause inflammation of crohn's, colitis, etc. The goal of Imuran (azathioprine) is to lower the WBC enough to stop the inflammation, but not enough to result in serious infections. That is why routine blood work monitoring is important. ...Read more
Imuran (azathioprine): "IMURAN (azathioprine) should not be given to patients who have shown hypersensitivity to the drug. IMURAN (azathioprine) should not be used for treating rheumatoid arthritis in pregnant women. Patients with rheumatoid arthritis previously treated with alkylating agents (cyclophosphamide, chlorambucil, melphalan, or others) may have a prohibitive risk of malignancy if treated with IMURAN (azathioprine)." See: ...Read more
Blocks immunity: Imuran (azathioprine) is an immunosuppressive drug that works by blocking the proliferation of activated immune white blood cells (lymphocytes, monocytes, granulocytes, etc.). It is used to treat autoimmune diseases and less so transplant rejection. It can cause bone marrow suppression, liver toxicity, hair loss, nausea, vomiting, etc. You should discuss any side effects with your doctor. ...Read moreSee 1 more doctor answer
Low blood counts: The commonest reason to lower the dose is decreased white cell count. Caancers particularly skin cancer are increased in patient using Imuran (azathioprine) after organ transplantation. This is seen after several years on the drug and an annual dermatological check is recommended. ...Read more
How much time does it take for imuran/azathioprine to completely leave your body after stopping the medicine?
Drug elimination: Well.....it will depend on few factors.....how your liver and kidneys are....remember this drug has a very short half live.... Around 5 hours.....but its toxicity will depend on what other medications you are on while on imuran (azathioprine)....for example antigout drug allopurinol.....even aspirine or antihypertensive meds for example commonly used and very good drug losartan....none in few hours in your blood ...Read more
Not usually: The immunosuppressive agent can cause toxicity to the liver but not usually the gallbladder. You should discuss with the doctor prescribing the medicine for you. ...Read more
It is dose dependent: The toxicity depends how much you are taking and how long.... . It also depends what other med you are on i.e. Med for gout.....if you are with antigout....bone marrow suppression can be a serious condition. .......infection,liver function alteration,cancer etc.....low dose should not be a problem and are given for many conditions and patient can be on for long time with regular follow ups ...Read more
Sometimes: Imuran (azathioprine) seems to be effective in a small subset of patients with Crohn's (likely fewer than 40%). At the moment it's difficult to predict who will respond in the long term. But as it can be safely used with monitoring, it's often worth trying. ...Read moreSee 1 more doctor answer
Imuran (azathioprine): See: http://www.drugs.com/sfx/imuran-side-effects.htmlGet a more detailed answer ›
Immune suppression: Imuran (azathioprine) is a medication which suppresses your immune system. This can lead to an increased risk of infections such as viruses and colds. Other side effects are less common, such as nausea and vomiting, suppression of bone marrow function (especially white and red blood cells), pancreas inflammation and liver dysfunction. Long term use may be associated with certain types of cancers (lymphoma, skin) ...Read more
May be, but...: Wheatgrass & spiruina are foods supplements and not well tested in combined use with the prescribed Imuran. Hence, no one could ever give you an definite answer saying yes or not. If in doubt, consider if Imuran or food supplement is more important for you - priority, for which you may ask your doc, and be off supplement and see since nowadays most folks are not malnutritioned. Best... ...Read more
Bone marrow toxicity: Imuran (azathioprine) is a non specific immunosuppressive drug that works by blocking the proliferation of activated immune white blood cells (lymphocytes, monocytes, granulocytes, etc.). It can cause too much bone marrow suppression, liver toxicity, hair loss, nausea, vomiting, etc. You should discuss any side effects with your doctor. ...Read moreSee 1 more doctor answer
Historical: You bring up an ancient approach to treat ms in the recent past when all we had were self injectable meds. To improve outcomes, a european study looked at better control with betaseron, and added Imuran and steroid pulses. Unfortunately, did not work well and now, we have stopped using this and turned to the newer more potent meds, such as gilenya, tysabri, (natalizumab) and tecfidera. ...Read more
Disease may flare: Imuran (azathioprine) is a non specific immunosuppressive drug used in several autoimmune diseases (i.e. Inflammatory bowel disease) and transplant rejection. It usually suppresses the formation of white blood cells. If suddenly stopped the reason it was prescribed may suddenly flare. You should discuss changing the dose with your doctor. ...Read more
Mostly none: If you're taking Imuran (azathioprine) at the doses used to teat ibd, most have no side effects. Few are allergic and develop pancreatitis. The biggest issue is to monitor blood counts to make sure WBC doesn't go too low, which can lead to serious infections. Occasionally liver enzymes can go up, which is reversible. Very rarely associated with malignancy. You should have tpmt checked before starting. ...Read more
Difficult to tell: It is always difficult to tell what the cause of pancreatitis is which is why a lot of lab work is done. Doctors take a medical history, check triglyceride levels, perform imaging like ultrasound or CT, and review medications. If there is no other explanation and the patient is on a high risk medication known to cause pancreatitis, then we will recommend discontinuing that drug. ...Read more
My temperature is 97.6 and i'm currently taking imuran, (azathioprine) an immunosuppressant. Should i be concerned?
No: The most common side effects of Imuran (azathioprine) are nausea/vomiting (~12%) which may be accompanied by malaise, diarrhea. Drowsiness is really not common with this drug. This drug is used for many conditions, so the drowsiness may also be a result of other conditions. Please see your doctor for evaluation and continuous care. Take care. ...Read more