Doctor insights on:
Monospecific Ab.: Monoclonal antibodies are those that are produced by the identical immune cells that are descended from the same parent cell. They produce anitibodies that bind to only one epitope or site on an antigen. This means that they are monospecific. This makes them useful in things like research because they can isolate a strain purely and completely. ...Read more
My serum test is negative for endomysial antibody iga, ttg tissue transglutasminase iga, gliadin antibody igg. But positive for gliadin antibody iga?
Ebvab VCA IgM <36 (range 0-35.9), ebvearly antigenab IgG 37 (0-8.9), ebvab VCA IgG >600 (0-17.9), EBV nuclearantigenab IgG 409 (0-17.9) mono? No mono?
You had mono...: Your mono-like symptoms likely prompted the testing- i hope you are starting to feel a little better. Testing for different antibodies (igm and igg) against ebv, requires careful interpretation. In early phases of infection, the igm level peaks first followed by a decline; levels of igg peak afterwards, and may remain elevated for quite a while. ...Read more
IVIg, SCIg: Immunoglobulins are proteins that aour body produce with the major function of neutralizing microbes. They are also called antibodies. Some people are congenitally deficient and receive a concentrate of immunoglobulins prepared from blood donors. When given intravenously is called ivig, given subcutaneously is scig. Another function is anti-inflammation, and is used in autoimmune conditions. ...Read more
Cells vs, animals: A monoclonal antibody is produced by in-vitro manipulation by expoanding a single cell making a desired antibody. Polyclonal antibodies are usually derived from immunizing an animal and colletcting its blood/serum containing the antibody. Polyclonal antibodies are a mixture of a large number of different cells. ...Read more
Protein, antibody: An immunoglobulin, also called an antibody, is a protein that binds susbtances to eliminate or neutralize them. Most of immunoglobulins are in the blood, but also in the lining of the respiratory tract and the gastrointestinal tract. Immunoglobulins are produced with small variations that allow them to bind the millions of different microbes. There are 5 types; igg, igm, iga, IgD and ige. ...Read more
Elevated EBV ab VCA IgG <8 and EBV nucleaer antigen ab IgG test 4.2. & anti-dna(ss)igg ab qn ( 119)& c react protien(5.6) what are implications?
Nothing.: Ebv antibodies indicate you had a previous infection, but not active. The c-reactive protein needs a units indicator - that is either normal or somewhat elevated. The anti ss dna is extremely nonspecific and very rarely indicated; I have no idea why that was ordered, discuss with your doctor. ...Read more
They don't usually: Antibody does not usually kill an antigen but binds it. The attachment may then, under certain circumstances , triggers the release of certain mediators or the influx of body cells (cytotoxic lymphocytes, macrophage etc) to do the job of killing. This is a very simplistic answer to a complex question however. ...Read moreSee 1 more doctor answer
Hepatitis c (HCV) antibody is reactive. The hepatitis C Recombinant Immunoblat Assay(riba) confirmation test is non reactive.Is antibody false positiv
Well : A positive hepatitis C antibody test with a negative or in a test usually is not a false positive that usually means someone had hepatitis C infection and their body cleared the infection and they are now immune to hepatitis C. Do a Healthtap visit or see a primary care physician for specific diagnosis ...Read moreSee 1 more doctor answer
Celiac disease? Biopsy needed?Endomysial AB IGA Negative,Gliadin AB IGA High=16, Anti-Gliadin IGG A B High=22, t-transglutanimaze IGG Normal 1.7, t-transglutanimaze igA Normal 3.1, IGA Normal 186
All the same: Antibodies are complex protein molecules made by the immune system. The have a variable portion that can be made specific to a target. "monoclonal" refers to antibodies whose variable regions are all the same. When directed at specific biological targets, e.g. Inflammatory mediators, they can be used as drugs ("biologics") to modify diseases. ...Read moreSee 1 more doctor answer
HBV test results: Hepatitis B Surface Antigen: Nonreactive; Hepatitis B Core Antibodies: Reactive; HBV PCR: Negative. Need any medication or vaccine?
Excellent question: and your story stumps many a doctor, often! :) a lot of the recommendations depend on - are you someone with risk factors for HBV? is this the first time that it has been checked? are your liver enzymes normal? are you about to undergo any procedures/ treatments that could put you at risk for HBV? If you have no sig risk factors, yes, I'd vaccinate you if there's potential for exposure. ...Read more
Do inactivated rabies vaccines elicit cell mediated immunity(t-cells) aside from just antibody production?
Activated rabies vac: Yes. They activate dendritic cells and presumptively enhance immune function in that fashion. J virol 2011 feb; 85(4) :1634-44. ...Read more