Doctor insights on:
Immunosuppressive Therapy Side Effects
Mostly infusion rxns: Rituxan is given intravenously slowly at first to look for common immediate reactions like chills, fever, shakes, itching, hives, headache all of which could be prevented or lessened by giving premedications like Benadryl (diphenhydramine) and steroids. Reactivation of hepatitis b, lowering resistance to infections, rapid destruction of tumor cells causing i'll effects to organs (tumor lysis) can also occur. ...Read more
Watch for infections: Orencia (abatacept) is approved to treat moderate to severe rheumatoid arthritis. Typically it is prescribed when disease modifying anti rheumatic drugs (DMARDS) are not effective. The most common DMARD is methotrexate. Orencia (abatacept) is usually prescribed in combination with methotrexate but sometimes is given alone. Orencia (abatacept) is quite effective for many but not all people. It's main side effect: infections. ...Read moreSee 1 more doctor answer
Numerous: Multiple classes of anti-retrovirals each containing several different drugs and each with a wide spectrum of side-effects. Too much information to be transmitted in this venue. If you are concerned about a specific compound, rephrase the question. ...Read more
None: No interactions.Get a more detailed answer ›
Plenty : XX oral dos: Methotrexate is a surprisingly effective drug for many forms of arthritis and the consensus 1st choice for RA by the acr and eular (european). The oral dosage is more problematic because of variable absorption and first-pass effect through liver. It is completely absorbed with sucutaneous injection and doesn't bolus liver. Hair loss can be a problem. Everyone should take 2mg of folic acid. ...Read more
Many: The side effects are too many to list here but some of the more common ones (occur in >10% of patients) are fever, fatigue, headache, insomnia, depression, emotional lability, rash, nausea, diarrhea, weight loss, anemia, muscle aches, joint pains, flu-like syndrome and injection site reations. ...Read more
Heart failure: About 4% of women treated with Herceptin (trastuzumab) develop some weakness in their heart. This decrease in heart function is almost always reversible when the drug is stopped. Other side effects of Herceptin (trastuzumab) can include allergic reaction, fatigue, headache and diarrhea. Most of my patients have no side effects! ...Read moreSee 1 more doctor answer
Many: It is an immunosuppressive agent so infections can occur. Gi symptoms such as nausea and vomiting and diarrhea are reported. Bone marrow suppression and pancreatitis are other severe known complications associated with this agent. Cancers (especially skin cancers) are more common in people taking immunosuppression drugs. ...Read more
Improved eczema: Flucoinolone is a potent topical steroid that can improve allergic skin issues like eczema. Typically the more potent ones should not be used on children, on the face, in the armpits or groin as that skin is thinner and some steroids if used there chronically can cause stretch marks. Often the topical steroids really help but the eczema can recur once stopped. They are wonderful in a flare! ...Read more
How long? Which?: Most expiration dates are about half of the actual time that the compounds remain active, but this may not guarantee their activity. Side-effects of the products of these compounds as they deteriorate vary with the compound, but very few if any have serious toxicities. Best to throw them out if they have expired. Better than taking a chance they are inactive or toxic. ...Read more
Infliximab injection: See: http://www.drugs.com/sfx/infliximab-side-effects.htmlGet a more detailed answer ›
Bleeding: There are risks associated with tpa (alteplase). Complications include bleeding into the brain, other types of serious bleeding (e.g., gastrointestinal), and death. It is important to weigh the possibility of benefit against the possibility of harm. In most cases tpa (alteplase) is safe and makes a positive impact on the outcome in stroke patients. ...Read moreSee 1 more doctor answer
Many; see below: Many of patients experience flu-like symptoms like fever, chills, headache, fatigue, and weakness within 1-2 hours of taking the medication. Symptoms like irregular heartbeat, chest pressure or tightness, hallucinations, irritability, insomnia, depressive mood, and suicidal thoughts may also occur. It’s important to report any of these to your doctor. ...Read more
Cetuximab injections: See: http://www.drugs.com/erbitux.htmlGet a more detailed answer ›
Drugs turn off Immunity: Our immune system is our natural defense mechanism to foreign invaders like bacteria, viruses and fungi. Unfortunately, it also "defends" against foreign organs that are transplanted. We use a variety of drugs to suppress different portions of that complicated system - trying to prevent the organ from being rejected without incapacitating the rest of your defenses. ...Read moreSee 2 more doctor answers
I have Dermatomyositis and have been receiving immunosuppressive therapy for about 6 years now. Yuck! I am very careful about cleanliness and wash my?
Good: It's good to hear that you take care of yourself and pay close attention to hygiene. Perhaps it is time to ask your rheumatologist about your dermatomyositis and how to measure the activity of the disease. If the disease is well-controlled, it may be possible to reduce or even stop the immunosuppressive medication. ...Read more
Skin and lymphoma: Skin cancer is already at an epidemic rate - immunosuppression increases that risk. The longer you take immunosuppression, the greater the risk of skin cancer. All immunosuppressed patients should have an annual skin check by a knowledgeable provider. By 5 years, 50% of australian patients had skin cancers (due to intense sun and very light skin). Lymphoma is second most frequent. ...Read moreSee 1 more doctor answer
Yes: Prognosis of aplastic anemia depends on age (younger is better) and the severity of the blood count abnormalities. While younger patients may be referred for stem cell transplant, older patients, perhaps those over 40, are given immunosuppressive therapy. Response rates are over 60% and durable remissions occur quite frequently. ...Read more
I don't want to try yag laser because its side effects , is there any therapy i can use to get better?
For what?: Yag lasers are used for many things. What are you contemplating? ...Read more
Interferon: Treatment-related side effects are nearly universal most common: fatigue (interferon and ribavirin) flulike symptoms: fever, headache, muscle ache (interferon and ribavirin) mild anxiety (interferon) skin rash (ribavirin) depression (interferon) gastrointestinal symptoms: nausea, diarrhea (interferon and ribavirin) monitoring for severe side effects (eg, marked anemia) is an important part of trea. ...Read moreSee 1 more doctor answer
Too many: Side effects depend the area of the body which is being radiated- dry mouth & mouth sores (oral cancers), diarrhea (pelvic radiation), shortness of breath (lung radiation), hair loss (brain radiation), stomach ulcers and bleeding (stomach radiation). General side effects can include severe fatigue, low blood counts, skin rash and discoloration. ...Read moreSee 1 more doctor answer
Oxygen as a drug: Mostly related to delivery through nose including dryness/bloody noses. This can create free radicals so it can contribute to negative changes to the airway itself. ...Read more
Wallet shrinking: I know of no side effects from this treatment other than changing of behavior. Some might not like the changes but I suspect most would appreciate it. One side effect might be breaking up abusive and controlling relationships and decreased neediness. Which side are you on? ...Read more
Many...: • pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating; • easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin; •fever, chills, body aches, flu symptoms, sores in your mouth and throat; • severe or ongoing vomiting;• stomach pain, dark urine, clay-colored stools, jaundice (yellowing of the sk. ...Read more
See below: Radioprotectants are really only useful if they offer differential radioprotection to normal tissues and not tumor cells. That's really the problem. A general radioprotectant would benefit the cancer cells as much as normal cells thus you haven't changed the therapeutic ratio. ...Read moreSee 2 more doctor answers
Can you let me know how many days does radiation therapy side effects need to recover completely?
6-8 wks: Following radiation to an organ site, there is a certain degree of edema and scarring. Like going into heavy sun and receiving sunburn. Effect not the same day after sun exposure but builds up over several days. If surgery needed to an organ receiving RT, one needs 6-8 wks before side effects minimized so that following resection, suture repair can be employed with minimal side effects. ...Read more
Is it acceptable to discontinue chemo after only two doses (due to side effects) and continue only with radio therapy?
Discuss with doctor: You should discuss this with your oncologist and radiation oncologist. The goal(s) of treatment are important in making a decision such as this. ...Read more
Are there bad side effects to valtrex (valacyclovir)? Why would anyone decide not to stay on it for daily suppressive therapy?
Is there anything i can do to decrease side effects for zoladex (goserelin) or make them more manageable? Add back therapy will be used.
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