Doctor insights on:
Immunosuppressive Drugs Rituxan
Rituximab: Rituximab is one class of immunosuppresant therapy. It is an chimeric (composed of human and animal) monoclonal antibody directed against a surface marker (cd20) on your b-cells. Your b-cells naturally produce your own body's antibodies to help fight infections. There are other types of immunosuppresants which have different targets than b-cells, such as t-cells, and cytokines such as tnf-alpha. ...Read moreSee 1 more doctor answer
Immunosupressive : Immunosuppressive agents are agents that suppress immune function by one of several mechanisms of action-through t cell activation, ihbition of b cell helper, dna inhibition etc, such as cyclosporine, tacrolimus, sirolimus, corticosteroid. Rituxan (rituximab) is one of immunosupressive agents where it works by binding the cd 20 receptors on the b cell-lymphocytes which eventually leads to the cell’s death. ...Read more
To decrease immunity: Immunosuppresive agents are drugs that decrease immune function. While in most situations this would be undesirable, with certain conditions where the immune system is overactive or too aggressive, these drugs may be proper. Examples include to prevent rejection of transplanted organs, in autoimmune conditions to prevent tissue destruction, and in diseases with chronic inflammation like asthma. ...Read moreSee 1 more doctor answer
Immune disorders: Immune suppressive drugs works just as they sound- to suppress the type of overactive immune responses causing the illnesses . The type of drug used would depend on the type of immune reactions specific to that disease. ...Read more
Prednisone does: Prednisone does cause weight gain, along with other side effects. The doctor who is prescribing the immunosuppressives can list the medication options for a patient, and also list the more common side effects. Then, both the patient and doctor are aware of what to expect when some of the medications are used. ...Read more
Risk vs. Benefit: It depends on the drug.Get a more detailed answer ›
Is it true that there are new techniques to remove antigens of donated organs to avoid rejection instead of using immunosuppressive drugs?
Not aware of any: Monoclonal antibody therapy, which blocks immune responses of key white cells (T-cell lymphocytes) is relatively new, but I am unaware of novel techniques to remove antigens from donor organs. You may want to discuss this with a large medical center transplant program if you are interested in new therapies or even in participating in a research study. ...Read more
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