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Doctor insights on: Immunoglobulin Profile Serum

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What changes are seen in the immunoglobulin profile after a splenectomy?

What changes are seen in the immunoglobulin profile after a splenectomy?

Usually none: no changes in humoral immunity usually happens after splenectomy, however splenectomized patients should receive certain vaccines, pneumococcal, meningococcal, h flue and flu, ask your doctor about them, good luck ...Read more

Dr. Robert Dracker
97 doctors shared insights

Immune Globulin (Definition)

The immune globulins are a class of blood proteins elaborated by the immune system to fight infection, and then remember the antigens of the infecting agent to use for ...Read more


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Immunoglobulin a, qn, serum. came back 203 what does that mean?

Immunoglobulin a, qn, serum. came back 203 what does that mean?

Normal: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, your IgA level is normal. ...Read more

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What is immunoglobulin g, qn, serum? My results came back low for subclass 3 out of the four.

Don't worry: I presume that these tests were done because of recurrent sinus or lung infections. Ig g is a measurement of the major antibody type which is involved in fighting against infections. If the total is normal but the igg3 is low, it has little meaning. But if your total igg1 is low, then this may be of concern. ...Read more

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Is a serum immunofixation test focused on monoclonal immunoglobulins but can also detect polyclonal ones or just the former? Thanks.

Is a serum immunofixation test focused on  monoclonal immunoglobulins but can also detect polyclonal ones or just the former? Thanks.

Depends: This depends on what you are looking for. If you are just interested in antigen binding, any specific antibody would bind to the antigen. ...Read more

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What does it mean if I have high immunoglobulin m qn serum?

Waldenstrom's Dz: An elevation of immunoglobulin m (igm) in the serum esp. If monoclonal (of one kind) raises the possibility of waldenstrom's macroglobulinemia - a malignancy affecting lymphocytes or plasma cells that produce this abnormal IgM protein causing symptoms of hyperviscosity - confusion, shortness of breath, stroke, kidney damage etc. ...Read more

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My 3 year old immunoglobulin g qn serum level is high mg/dl 453-916 what does this mean?

IgG: It likely means nothing. Are they checking it for a possible immune deficiency or chronic/recurrent infections? You need to have a bit more information to truly get a better answer. ...Read more

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I have a very low igg3 and igg4, along with a very low immunoglobulin m and a high serum amyloid a - what does this mean?

See immunlogist: The low igg3 and igg4 in and of themselves may not mean much if your igg1 is normal. The fact that you also have low igm suggests that there may be an immune disorder. The high serum amyloid a likely signifies inflammation in your case. www.ncbi.nlm.nih.gov/.../10608507?. ...Read more

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I recently had a celiac panel done and it came back negative. However the immunoglobulin a, qn, serum level was low at 59. Is this serious?

I recently had a celiac panel done and it came back negative. However the immunoglobulin a, qn, serum level was low at 59. Is this serious?

Unlikely: Low IgA occurs in about 1/333 people. Most people with this isolated deficiency do not have problem. A very low IgA level may make a celiac test based on IgA antibody false-negative- ie. The disease is there but the test fails to detect it. However yours is not low enough. ...Read more

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My blood work indicated I have low Immunoglobulin A, QN, Serum and Low Igg 1 and 3as well as 14 low Pneumococcal types; could this be why I have fatig?

Possibly: The fatigue can be due to recurrent respiratory infections, secondary to the immunoglobulin defiencies, and the low antibodies titers, kindly keep the follow up with an allergist/immunologist preferably in a tertiary care facility, you may need intravenous immunoglobulins replacement therapy, wish you wellness ...Read more

Immunoglobulin (Definition)

Immunoglobulins are antibodies produced by b cells. They have a y shaped configuration. They are involved in protecting us ...Read more


Serum (Definition)

Serum is the component of blood that does not contain cells or clotting factors. It does contain electrolytes an ...Read more