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Doctor insights on: Immunoglobulin Profile Serum

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Inorgan.Phosphate0.77, serum total protein63, serum globulin14, all slightly low. Norm. Calcium &albumin.Tsh9.25, known hypothyroidism. Further tests?

Inorgan.Phosphate0.77, serum total protein63, serum globulin14, all slightly low. Norm. Calcium &albumin.Tsh9.25, known hypothyroidism. Further tests?

TSH is WAY high!: Must get on a higher dose of synthroid (thyroxine). This can be life threatening, get treated asap, ! other thyroid tests need to be done to know what needs to be done, and to come to a diagnosis. ...Read more

Dr. Robert Dracker
103 doctors shared insights

Immune Globulin (Definition)

The immune globulins are a class of blood proteins elaborated by the immune system to fight infection, and then remember the antigens of the infecting agent to use for ...Read more


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Total protein 8.3, serum albumin 4.2 , serum globulin 3.8, albumin globulin ratio 1.2.. Is this abnormal?

Total protein 8.3, serum albumin 4.2 , serum globulin 3.8, albumin globulin ratio 1.2.. Is this abnormal?

Abnormal labs: It would be helpful that for the labs mentioned above. If you. Can find the normal range or reference range and list it than our answer can be more educated and helpful. The reference range does vary from one lab to another. ...Read more

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Blood results: alt/sgpt serum level=40 iu/l, serum alkaline phosphatase=43 iu/l, serum bilirubin level=2 umol/l, serum urea level=2.3 mmol/l. Normal?

Blood results: alt/sgpt serum level=40 iu/l, serum alkaline phosphatase=43 iu/l, serum bilirubin level=2 umol/l, serum urea level=2.3 mmol/l. Normal?

Normal: It is very important to know why these were drawn in what sounds to be an otherwise healthy 19 year old. Did you expect to find something wrong? ...Read more

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Plasma Vitamin D <4.2 ng/mL Serum Vitamin B12 -197 Serum TSH-2.805 Serun Alkaline Phosphatase-356 WBC-3300 MCV-103 MCH-34 Platelet-141k?

Plasma Vitamin D  <4.2 ng/mL
Serum Vitamin B12  -197
Serum TSH-2.805
Serun Alkaline Phosphatase-356
WBC-3300
MCV-103
MCH-34
Platelet-141k?

Need Vits D3 and B12: You are severely deficient in Vitamins D3 and B12. I recommend 10,000 IU of Vit D3 per day, and 1,000 mcg methylcobalamin each day. Your D3 levels should be 60-70 ng/dl. ...Read more

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LP Done. Monocytes 1%, Serum IgG 587/mg/DL,Albumin 4100ml,IGG Index 1.1mg,WBC 23/mm3,RBC 1/mm3, CSF IGG 3.6 mg/DL,Lymphocytoid 97%, protein, neutrophils, glucose, CSF albumin all norm. Any ideas?

LP Done. Monocytes 1%, Serum IgG 587/mg/DL,Albumin 4100ml,IGG Index 1.1mg,WBC 23/mm3,RBC 1/mm3, CSF IGG 3.6 mg/DL,Lymphocytoid 97%, protein, neutrophils, glucose, CSF albumin all norm. Any ideas?

CSF Results: If I am reading the results correctly, there appears to be a mononuclear pleocytosis with normal protein, glucose and essentially normal immune response. The fluid analysis cn be seen in many disorders including viral meningitis. Need additional information. ...Read more

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Protein Total Serum 8.7 Globulin Serum 4.20 Albumin/ Globulin Ratio 1.07 ALP 132 Urea/ CreatinineRatio 18.54 rest normal . Any worries here ?

Need more info.: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, there is no immediate concern, however, your globulin level may be higher than normal and you should discuss it with the doctor who ordered the tests. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more

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Immunofixation, Serum FAH = Monoclonal IgG kappa immunoglobulin. Beta FAH = 10.5% Abnormal band, immunofixation to follow. I'm IgA deficient too. ??

Immunofixation, Serum FAH = Monoclonal IgG kappa immunoglobulin.   Beta FAH = 10.5% Abnormal band, immunofixation to follow. I'm IgA deficient too. ??

Possibly: If I am understaning this right you have a monoclonal protien band? The most important next steps here would be to identify the band (immunofixation) and then perfrom quantitvaive immunoglobulin levels. IF there is a monoclonal band, you may very well have reciprocal depriciation of alternative immunoglobulins and IgA deficiecny with an IgG monoclonal protein is possible. ...Read more

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Serum free light chain test shows normal kappa (8.7mg/dl), low lambda (3.80), high kap/lam ratio (2.31). Serum $ urine electrophoresis show no monoclonal protein, nor does serum immunofixation. Likely MGUS, myeloma, or admyloidosis? CBC/met panel ok.

Serum free light chain test shows normal kappa (8.7mg/dl), low lambda (3.80), high kap/lam ratio (2.31). Serum $ urine electrophoresis show no monoclonal protein, nor does serum immunofixation. Likely MGUS, myeloma, or admyloidosis? CBC/met panel ok.

False positive rate: There is 30% or so false positive rate of kappa/lambda ratio in people without MGUS, myeloma or other disorders. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more

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Increased aldolase, complement c3/c4 serum, sed rate, c-react. Protein, beta globulin, monocytes, bun/creatin low mcv-mch, vit d-possible causes?

Increased aldolase,  complement c3/c4 serum, sed rate, c-react. Protein, beta globulin, monocytes, bun/creatin low mcv-mch, vit d-possible causes?

Complicated: When i was doing clinical medicine, these were collectively sort of the flags for sarcoid disease but I am not saying that's the case here. This is because sarcoid is a diagnosis of exclusion so the advice is to rule out other diseases with additional diagnostic tests which can be done by a primary care physician or rheumatologist. ...Read more

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What causes elevated histone antibody levels in bloodworm?

What causes elevated histone antibody levels in bloodworm?

???: I am not sure about a correlation with blood worm and this antibody? Anti-histone antibodies are autoantibodies that are found in 50%-70% of patients with systemic lupus erythematosus (sle), but I am unawre of a correlation with blood worms? Posibly a pathologist may know of a correlation. ...Read more

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IgA TTG POSITIVE low level of ferritin?

IgA TTG POSITIVE low level of ferritin?

Gluten sensitivity: Typical findings for gluten intolerance with reduced iron absorption and thus the low ferritin. Need to avoid gluten and take some iron supplement (or even shots) ...Read more

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What causes high globulin, but low globulin albumin ratio?

What causes high globulin, but low globulin albumin ratio?

Liver blood tests: The liver is an amazing organ- it does many things including making proteins your body needs. Albumin is a major protein product of the liver. Chronic illness can cause that to decline- esp. if you're not eating. Globulins are other proteins usually made to fight diseases like infections- perhaps you've been fighting an illness for a few weeks/months that explain this pattern. ...Read more

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Antitissuetransglutaminase iga 0.5 u/ml is this ok?

Antitissuetransglutaminase iga	0.5 u/ml is this ok?

Probably: If this is considered normal value by your lab then it is normal. However this test is only reliable when you are consuming gluten. If you have avoided gluten for some time, then you will need to get alternate tests. ...Read more

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Total ck, sed rate, ana, ip ace, serum protein panel normal but gamma globulin (.6) cortisol am (30.8) Hx of low vit d and K. What could this mean?

Total ck, sed rate, ana, ip ace, serum protein panel normal but gamma globulin (.6) cortisol am (30.8)
Hx of low vit d and K. 
What could this mean?

Not much-: An important thing to remember is that lab results are not useful unless there is a clinical context. Advice is based on focusing on the patient, not the numbers. Though you mention a history of low vit D and K, did symptoms exist when the labs were drawn? Why were they drawn in the first place? Otherwise, it is best to ask your ordering doctor what the results mean. ...Read more

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Do these results mean low immunity? Diptheria Titer 0.95 int_units/ml ref range <0.10 and Tetanus Igg Titer 0.62 int_units/ml ref range <0.10

Do these results mean low immunity? Diptheria Titer 0.95 int_units/ml ref range <0.10 and Tetanus Igg Titer 0.62 int_units/ml ref range <0.10

It depends: on why this child required diphtheria and tetanus immunoglobulin titers in the first place. Most children go through the 3 stage DPaT vaccinations and never require Ig titers. Those titer concentrations mean that the necessary immunoglobulins against those conditions were undetectable in assay. Whether that means low immunity depends on the situation and the child. Ask MD that required titers. ...Read more

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Lupus panel negative. Sed rate 30 should b under 20. Ana positive w/ spec pattern. Serum protein electrophoresis test normal. Cbc ok. Metabolic ok.?

Lupus panel negative. Sed rate 30 should b under 20. Ana positive w/ spec pattern. Serum protein electrophoresis test normal. Cbc  ok. Metabolic ok.?

Any joint pain?: Positive ANA and elevated sed rate. If you have joint pains it would be advisable to follow up with a rheumatologist. You have some kind of inflammatory process going on. Both test are very nonspecific and further work-up is needed. ...Read more

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Immunoglobulin (Definition)

Immunoglobulins are antibodies produced by b cells. They have a y shaped configuration. They are involved in protecting us ...Read more


Serum (Definition)

Serum is the component of blood that does not contain cells or clotting factors. It does contain electrolytes an ...Read more