Doctor insights on:
Immunoglobulin Profile Serum
Normal: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, your IgA level is normal. ...Read more
Likely nothing: You IgG level while at the low side is still within normal limits. If you do not have any symptoms, do not worry about the number. You may consult this site for info on this topic: https://medlineplus.gov/ency/article/003545.htm ...Read more
Don't worry: I presume that these tests were done because of recurrent sinus or lung infections. Ig g is a measurement of the major antibody type which is involved in fighting against infections. If the total is normal but the igg3 is low, it has little meaning. But if your total igg1 is low, then this may be of concern. ...Read more
Is a serum immunofixation test focused on monoclonal immunoglobulins but can also detect polyclonal ones or just the former? Thanks.
Waldenstrom's Dz: An elevation of immunoglobulin m (igm) in the serum esp. If monoclonal (of one kind) raises the possibility of waldenstrom's macroglobulinemia - a malignancy affecting lymphocytes or plasma cells that produce this abnormal IgM protein causing symptoms of hyperviscosity - confusion, shortness of breath, stroke, kidney damage etc. ...Read more
I have a very low igg3 and igg4, along with a very low immunoglobulin m and a high serum amyloid a - what does this mean?
See immunlogist: The low igg3 and igg4 in and of themselves may not mean much if your igg1 is normal. The fact that you also have low igm suggests that there may be an immune disorder. The high serum amyloid a likely signifies inflammation in your case. www.ncbi.nlm.nih.gov/.../10608507?. ...Read more
I recently had a celiac panel done and it came back negative. However the immunoglobulin a, qn, serum level was low at 59. Is this serious?
My blood work indicated I have low Immunoglobulin A, QN, Serum and Low Igg 1 and 3as well as 14 low Pneumococcal types; could this be why I have fatig?
Possibly: The fatigue can be due to recurrent respiratory infections, secondary to the immunoglobulin defiencies, and the low antibodies titers, kindly keep the follow up with an allergist/immunologist preferably in a tertiary care facility, you may need intravenous immunoglobulins replacement therapy, wish you wellness ...Read more
I had an immunoglobulin g, qn, serum appear on my blood test result of 2364, yet my doctor said it's not an issue. Is he right?
Correct.: Look at the person. Look at the numbers only when they shed light on the person. ...Read more
What can cause the Sedimentation Rate-Westergren - 70; Complement C4, Serum - 53; Immunoglobulin M, Qn, Serum - 36; Complement, Total (Ch50) >63?
Immunofixation, Serum FAH = Monoclonal IgG kappa immunoglobulin. Beta FAH = 10.5% Abnormal band, immunofixation to follow. I'm IgA deficient too. ??
Possibly: If I am understaning this right you have a monoclonal protien band? The most important next steps here would be to identify the band (immunofixation) and then perfrom quantitvaive immunoglobulin levels. IF there is a monoclonal band, you may very well have reciprocal depriciation of alternative immunoglobulins and IgA deficiecny with an IgG monoclonal protein is possible. ...Read more
My 3 yr old took an allergy test her immunoglobulin e total was 12
immunoglobulin g qn serum total 1111 they said was high
immunoglobulin a 90 means
Immunoglobulins: Ige is the allergic antibody (this was normal). An elevated igg level might simply be if he was fighting an active infection at the time (this is a good sign). Iga protects mucosal membranes (sinus, lungs, GI tract, urinary tract) and his level is normal. Feel reassured that these labs look very good. ...Read more
I have the following and no definitive diagnosis..low(8.3)hgb,hct(25), require IV iron every 4-6 mo. lately immunoglobulin m,qn serum 415.FATIGUE?
SEVERE ANEMIA: Can cause the fatigue you are having. Hope you are under the care of a hematologist or other specialist to get the right DX. ...Read more
What would cause free kappa &free lamba to be high but ratio normal also Immunoglobulin M, Qn, Serum high. platelets steady rising & WBC high for 1yr?
Polyclonal gammopath: Something is stimulating all the B cell lines to produce a lot of antibodies. That general condition is called polyclonal gammopathy. It can be caused by a chronic infection (virus) or 9 other broad categories of causes (liver problems, connective tissue diseases, bone marrow disorder like Waldenstrom's, drugs/meds, autoimmune probs, misc). It's too much to go into here. Use Healthtap Prime to tal ...Read moreSee 1 more doctor answer
Yes, look different: Immunoglobulins also known as antibodies or gamma-globulins, are made are made of light chains and heavy chains. The different heavy chains are the bid difference between the immunoglobulins. Alpha1 abd alpha2 (IgA), Gamma 1-4 (IgG),Epsilon (IgE) and Delta (IgD). IgM is made up of 5 antibodies(a pentamer) arranged like the spokes of a wheel. It takes Xray diffraction optics to "see" the differen ...Read more
It depends: There are several types of immunoglobulin, igg, iga, IgM and ige. Having a "high" level of each of them could mean different things. It is also important to know if it is a "high" overall level, or a "high" level of a specific kind of igg, iga, igm, or ige. In general, a high ige means "allergy". High igg/a/m can mean different things depending on their specificity (total or specific). ...Read more