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Doctor insights on: Immunoglobulin A Subclasses

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Do foods contain immunoglobulins?

Do foods contain immunoglobulins?

Probably not...: Immunoglobulins (antibodies) are proteins used by the immune system to identify and eliminate unknown cells (like germs). They are found in body fluids like blood, tears, saliva, & breast milk. If foods are consumed raw or barely cooked, there is a chance that you are also consuming immunoglobulins from that animal. In most cases, the cooking or pasteurization process destroys these proteins. ...Read more

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Dr. Ben Glasgow
366 doctors shared insights

Immunoglobulin A (Definition)

Immunoglobulin a is an antibody that plays a critical in mucosal immunity found in mucosal secretions, tears, saliva, breast milk, the gastrointestinal tract, and the lungs. It helps prevent against sinus infections, ear infections, and pneumonia. More IgA is prodced per day than ...Read more


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Can anyone experienced with ivig (intravenous immunoglobulin) describe what one should expect?

Can anyone experienced with ivig (intravenous immunoglobulin) describe what one should expect?

General well tolerat: Ivig is a blood product that, in allergy, is used to treat those with immunodeficiency or a lack of igg ( that is the IG part of ivig). This is generally a well tolerated infusion but one can experience local discomfort from the insertion of the needle to infuse the ivig. Rarely, systemic reactions can occur including headache, nausea, hives and others. ...Read more

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Can you tell me about immunoglobulins: help me for biology?

See Below: Immunoglobulins are a type of protein made by your body to help protect it against infections. There are five types of immunoglobulins: IgA, IgD, IgE, IgG, and IgM. Each of these has a slightly different function in infection fitting. ...Read more

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What does low immunoglobulin g subclass 2 on blood work mean?

Low gamma globulin: By itself, a slightly low level of one igg subclass is a very nonspecific finding. A very low level would be worrisome, but really, what is needed is to look at this information in the context of vaccine responses to Pneumovax vaccine. If the functional antibodies made by the immune system are at normal levels, the gross levels of antibody are less worrisome. ...Read more

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Is it safe to take rabies immune globulin while pregnant or breastfeeding?

Is it safe to take rabies immune globulin while pregnant or breastfeeding?

Yes, IgG is safe: Immune globulin (igg) is concentrated antibodies, and helps protect against a variety of infections. It is safe for pregnant women, breastfeeding moms, and infants. Of course, there could be a rare allergic reaction on a rare occassion. Because IgG is purified from other people's blood plasma, there is also a very, very rare chance that something contagious could be transmitted in the injection. ...Read more

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Does intravenous immunoglobulin (ivig) infusions benefit someone with IgG defiency?

Possibly: If you are deficient and symptomatic (recurrent infections), they can possibly help your body fight infections better. Just because you have an igg deficiency does not mean your are immune deficient, however. Many people with low numbers have normal function and really are asymptomatic. ...Read more

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Is it possible for low immunoglobulin g (igg) to cause joint pain?

Is it possible for low immunoglobulin g (igg) to cause joint pain?

Yes: It depends on the type of deficiency (IgG subtype or total) and the level. You should see an immunologist or a rheumatologist with specific training in this area for evaluation ...Read more

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I just rec'd more bloodwork results. Immunoglobulin g subclass is low & lymphocytes absolute is low, what does it mean?

I just rec'd more bloodwork results. Immunoglobulin g subclass is low & lymphocytes absolute is low, what does it mean?

Deoends: Having one low igg subclass does not mean you have a problem. See a board- certified allergist (take your lab) and they can help you. ...Read more

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What does a high immunoglobulin mean ?

How high?: Minimally elevated probably not worth worrying about. Very or moderately high requires a test - serum immunoelectrophoresis - to rule-out multiple myeloma. Minimally high bears repeating twice a year. ...Read more

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Elevated immunoglobulin a means what?

Different things: Immunoglobulin could be elevated in many different conditions such as infections, inflammation , other chronic diseases as well as certain blood malignancies. My suggestion is to go to see your pmd and discuss further with your doc. If the level is significantly high or if it is suspicious then your doc can refer you to see a specialist- a hematologist/oncologist for further investigation. ...Read more

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What does low total immunoglobulin g levels mean?

See an immunologist: Immunoglobulin g (igg) is the main type of antibody found in the blood and is used by your body to help fight off infections. Some people may have a slightly low igg but be perfectly healthy. In others, it may indicate a problem with the immune system that can put one at risk for getting infections. An immunologist can perform additional tests to determine the cause of the low igg. ...Read more

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Are there any functional immunoglobulin subclasses assay available anywhere?

Are there any functional immunoglobulin subclasses assay available anywhere?

See A/I: A Board Certified Allergists should be able to provide proper guidance as to how to properly evaluate one's immune system. ...Read more

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What are structural differences of the immunoglobulins?

What are structural differences of the immunoglobulins?

Antibodies: Structural difference exist for all classes of antibody; igg, igm, iga, ige and igd. The structure of the antibody is insignificant when compared to the common ability to bind specifically to an antigen, typically a foreign protein or carbohydrate. Structural differences do account for different immune cell binding properties and also complement fixation (which helps in defense). ...Read more

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What is an immunoglobulin?

Part of immune sys: Immunoglobulins are proteins that we make that are part of our immune system. There are four main types igg, igm, IgA and ige all of which perform different functions. ...Read more

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What is an immunoglobulin fold?

Immunoglobulin fold: is part of the complex molecular structure of the Ig antibody ...Read more

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What does a high immunoglobulin mean ?

How high?: Minimally elevated probably not worth worrying about. Very or moderately high requires a test - serum immunoelectrophoresis - to rule-out multiple myeloma. Minimally high bears repeating twice a year. ...Read more

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Which is the largest type of immunoglobulin?

Which is the largest type of immunoglobulin?

IgM: Igm is the class of immunoglobulins which is the largest. The classes of immunoglobulin can be "sized" from largest to smallest is igm, iga, igd/ige, igg. ...Read more

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What is immunoglobulin diversity generated by?

Combinatorial: The genes that encode our antigen receptors (immunoglobulin and T cell receptors) are made up of hundreds of gene segments. These "V-D-J" segments recombine in potentially millions of combinations so that each immune cell has one final version that makes a unique receptor. This process is random but if the cell encounters its antigen it will be activated and can turn into a "memory" cell. ...Read more

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What does a high immunoglobulin level mean for you?

It depends: There are several types of immunoglobulin, igg, iga, IgM and ige. Having a "high" level of each of them could mean different things. It is also important to know if it is a "high" overall level, or a "high" level of a specific kind of igg, iga, igm, or ige. In general, a high ige means "allergy". High igg/a/m can mean different things depending on their specificity (total or specific). ...Read more

Dr. Robert Dracker
99 doctors shared insights

Immune Globulin (Definition)

The immune globulins are a class of blood proteins elaborated by the immune system to fight infection, and then remember the antigens of the infecting agent to use for ...Read more


Immunoglobulin (Definition)

Immunoglobulins are antibodies produced by b cells. They have a y shaped configuration. They are involved in protecting us ...Read more