Doctor insights on:
Immunoglobulin A Subclasses
IVIg, SCIg: Immunoglobulins are proteins that aour body produce with the major function of neutralizing microbes. They are also called antibodies. Some people are congenitally deficient and receive a concentrate of immunoglobulins prepared from blood donors. When given intravenously is called ivig, given subcutaneously is scig. Another function is anti-inflammation, and is used in autoimmune conditions. ...Read more
Immunoglobulin a is an antibody that plays a critical in mucosal immunity found in mucosal secretions, tears, saliva, breast milk, the gastrointestinal tract, and the lungs. It helps prevent against sinus infections, ear infections, and pneumonia. More IgA is prodced per day than ...Read more
Probably not...: Immunoglobulins (antibodies) are proteins used by the immune system to identify and eliminate unknown cells (like germs). They are found in body fluids like blood, tears, saliva, & breast milk. If foods are consumed raw or barely cooked, there is a chance that you are also consuming immunoglobulins from that animal. In most cases, the cooking or pasteurization process destroys these proteins. ...Read moreSee 1 more doctor answer
Antibody to one site: Monoclonal antibodies (mab or moab) are monospecific antibodies that are the same because they are made by identical immune cells that are all clones of a special parent cell. Monoclonal antibodies have monovalent affinity. That is, they bind to the same epitope/site. These can be used in treating cancer, autoimmune diseases, like rheumatoid arthritis, and in diagnostic tests, like western blot. ...Read more
Released immune cell: It is a single band shown on a special test of aprotein plasma cells or white cells called lymphocytes. It sometimes causes symtpoms and is usually nothing to worry about. But i presume your dr. Did this..So speak to him/her about whether any other tests are needed..Or followup with a specialist. ...Read more
Immunifixation identifies m spike as IGg Kappa polyclonal gamma globulin to consist mainly of IGg Kappa n Lamda with fair amounts of Iga means what?
?? Chronic Infection: M spike of polyclonal IgG (kappa & lambda) globulin mostly suggest chronic infectious or inflammatory process & rarely hematologic malignancies. You need a complete work up for ch. liver disease, hepatitis B/C, ch.bacterial, viral & fungal infection, HIV, autoimmune diseases & if negative then evaluate for hematological disorder. CHECK FOR Ch. INFECTION & HEPATITIS. Update me with your result. ...Read more
Protein, antibody: An immunoglobulin, also called an antibody, is a protein that binds susbtances to eliminate or neutralize them. Most of immunoglobulins are in the blood, but also in the lining of the respiratory tract and the gastrointestinal tract. Immunoglobulins are produced with small variations that allow them to bind the millions of different microbes. There are 5 types; igg, igm, iga, IgD and ige. ...Read more
General well tolerat: Ivig is a blood product that, in allergy, is used to treat those with immunodeficiency or a lack of igg ( that is the IG part of ivig). This is generally a well tolerated infusion but one can experience local discomfort from the insertion of the needle to infuse the ivig. Rarely, systemic reactions can occur including headache, nausea, hives and others. ...Read more
Is there CSF IgG subclass deficiency?
I have lowish IgG and IgG subclass deficiencies (1, 3, 4) and CSF IgG of 685 .
Maybe none: We need a lot more information. The positive ANA may not indicate anything. Just because there is a positive ANA does not mean you have lupus. The low IgA and low pneumococcal antibodies may not cause any symptoms. Your evaluation should include pneumococcal antigen stimulation to see if you are responsive. You need further evaluation. ...Read more
IVIg, SCIg: Immunoglobulins are proteins that our body produce with the major function of neutralizing microbes. They are also called antibodies. Some people are congenitally deficient and receive a concentrate of immunoglobulins prepared from blood donors. When given intravenously is called ivig, given subcutaneously is scig. Another function is anti-inflammation, and is used in autoimmune conditions. ...Read more
Unsure: In the past, the test was used to diagnose autoimmune diseases such as Lupus or Rheumatoid arthritis, but has largely been abandoned due to problems with the test. DNA is a double stranded (ds) molecule and anti-dsDNA is a marker for Lupus activity. However, IgG antibodies binding to single strand (ss) DNA occur in a high percentage of people without autoimmune disease. ...Read more
High KAPPA/LAMBDA LIGHT CHAIN/slightly high ratio.No Monoclonal protein immunofixation or serum electrophoresis. Is this a type of cancer?Normal WBC
Low gamma globulin: By itself, a slightly low level of one igg subclass is a very nonspecific finding. A very low level would be worrisome, but really, what is needed is to look at this information in the context of vaccine responses to Pneumovax vaccine. If the functional antibodies made by the immune system are at normal levels, the gross levels of antibody are less worrisome. ...Read more
Cells vs, animals: A monoclonal antibody is produced by in-vitro manipulation by expoanding a single cell making a desired antibody. Polyclonal antibodies are usually derived from immunizing an animal and colletcting its blood/serum containing the antibody. Polyclonal antibodies are a mixture of a large number of different cells. ...Read more
Celiac disease? Biopsy needed?Endomysial AB IGA Negative,Gliadin AB IGA High=16, Anti-Gliadin IGG A B High=22, t-transglutanimaze IGG Normal 1.7, t-transglutanimaze igA Normal 3.1, IGA Normal 186
Not Diagnostic of: These tests do not indicate a recent infection.IGM has to be above. 40 and IGG is positive which suggest you might have been infected in the past. Only tests to confirm acute infection are stool for H Pylori Antigen and/ or Urea Bresth Test.Or CLOE test during endoscopy . Discuss your case with your Doctor or Gastroenterologist ...Read more