Doctor insights on:
My son was diagnosed w/ hypogammaglobulinemia, doctor wants to start immunoglobulin therapy should I worry?
HYPOGLOBULINEMIA: Yes he needs immunoglobulin therapy, otherwise he mau succumb to infections. You should let them treat him. Do you know what kind of hypogobulinemia he has. But he needs treatment. ...Read more
I have CVID and mixed connective tissue disease. My Immunologist has me on Immuran, Remicade as well as Immunoglobulin therapy, really?
CVID: Hope you are better, yes, auto-immune disorders are common with CVID, and you seem to be on the right medicines for your case, just keep the regular follow up, and you will be fine. I didn't clearly understand your question otherwise, best wishes ...Read more
My 4 yr old son got immunoglobin e level around 2800 what is the procedure to attain normal what type of diagnosis is needed and what is the treatment?
No procedure: The appropriate way to allow natural reduction in a serum antibodies is to first determine what is causing it to be elevated (treat the root cause). Elevated IgE most commonly indicates some sort of allergy, or less commonly, parasitic infection. ...Read more
What is the preferred mode of treatment for guillain barre syndrome: immunoglobulin or plasmepheresis?
None: There is no specific replacement therapy for low igm. This value, the low igm, needs to be interpreted in light of the rest of one's immunoglobulins. ...Read more
Combinatorial: The genes that encode our antigen receptors (immunoglobulin and T cell receptors) are made up of hundreds of gene segments. These "V-D-J" segments recombine in potentially millions of combinations so that each immune cell has one final version that makes a unique receptor. This process is random but if the cell encounters its antigen it will be activated and can turn into a "memory" cell. ...Read more
Ready made antibodies: Immunoglobulins are mainly used to replace deficiency, in other words people with weakened immune systems who don't produce enough antibodies for whatever reason. Immunoglobulins are used also for other conditions to combat some immunologic problems not otherwise helped by other treatments ...Read more
Immunoglobulin: Gammar-p is a brand name for a preparation of immunoglobulin, primarily igg. It is indicated for igg replacement in persons with low or absent igg levels. Such preparations are occasionally used off-label for other conditions. ...Read more
Different things: Immunoglobulin could be elevated in many different conditions such as infections, inflammation, other chronic diseases as well as certain blood malignancies. My suggestion is to go to see your pmd and discuss further with your doc. If the level is significantly high or if it is suspicious then your doc can refer you to see a specialist- a hematologist/oncologist for further investigation. ...Read more
It depends: There are several types of immunoglobulin, igg, iga, IgM and ige. Having a "high" level of each of them could mean different things. It is also important to know if it is a "high" overall level, or a "high" level of a specific kind of igg, iga, igm, or ige. In general, a high ige means "allergy". High igg/a/m can mean different things depending on their specificity (total or specific). ...Read more
Each lab's different: Normal ige levels are 0.05% of the total immune globulins. That's pretty low. Each commercial lab establishes its own normal ranges for these values, so you have to look at the range stated on your lab report, but generally speaking, the upper limit of normal for most labs is around 40-70 u/ml. The lower limit of normal is close to zero, often stated as 4. Truly absent ige = immunodeficiency. ...Read more
See an immunologist: Immunoglobulin g (igg) is the main type of antibody found in the blood and is used by your body to help fight off infections. Some people may have a slightly low igg but be perfectly healthy. In others, it may indicate a problem with the immune system that can put one at risk for getting infections. An immunologist can perform additional tests to determine the cause of the low igg. ...Read more
Depends: The "normal ranges" for all lab tests include 95% of the "normal" population; thus, 2.5% of people are above the upper limit, and 2.5% are below the lower limit. There's nothing to worry about if your values are a little bit above the normal range, but a very elevated IgM could be a sign of a problem. You need to check with the physician who ordered the tests to interpret your results. ...Read more
See immunologist: Immunoglobulin A and G are major parts of the immune system that protect us from serious bacterial infections. Lacking IgA is fairly common but lacking IgG can lead to severe infections. An immunologist can assess the rest of the immune system and review in detail the types of infections you have had to determine what the best treatment approach would be. ...Read more
Low IgE is normal: Ige is present when you have allergies. A low ige usually is normal and just means you do not have a lot of allergies. ...Read more
Immunoglobulin A: Immunoglobulin a is an antibody that plays a critical in mucosal immunity found in mucosal secretions, tears, saliva, breast milk, the gastrointestinal tract, and the lungs. It helps prevent against sinus infections, ear infections, and pneumonia. More IgA is prodced per day than all other antibodies combined. ...Read more
IgE level: Ige is an antibody increased in patients with allergies. Allergen specific ige levels often increase after exposure to a trigger such as a food, pollen season, or pet and decrease as the allergen is avoided. However, some patients with allergies have normal ige levels and those without allergies can have elevated ige levels (such as those with parasitic infections). ...Read more
IgE Levels: Dear Albert: It is difficult to address your question accurately. IgE is checked if allergy is suspected. However, the amount of IgE doesn't necessarily predict the severity of an allergy. For this reason, your doctor will interpret the results in comparison with your symptoms and other allergy tests. All the best! Nisha ...Read more
Don't worry but first: Thing I would be wondering is why did you have those tests done? Are you having recurrent infections? (not just "regular colds"?),,, but if you were my pt. First thing I would do is repeat the tests to confirm results. If you are having recurrent sinus infections, bronchitis, etc & the repeat tests are similar, next step would be see an allergist/immunologist to further evaluate. Good luck ...Read more
Check this link, would describe the complex market, supply and demand issues
http://aspe. Hhs. Gov/sp/reports/2007/IGIV/execsum. Htm ...Read more
Hard to know: Without more information, it is difficult to know if the levels are low due to lack of production (primary immune deficiency syndrome, medication side effect) or loss of antibodies (protein losing gastrointestinal disease). Also, most people will do well with these levels, but it would be important to know if you have had any recent, or a long history of recurrent, infections. ...Read more
Related often: Eosinophils fight off certain bugs like helminths and also are important for allergic reactions. Ige is an antibody which is produced when you are allergic or sensitized to something. People with allergies, asthma, eczema often have high ige and sometimes high eosinophils. If they are very high then some very rare diseases can be considered (hies). ...Read more
See A/I: A Board Certified Allergists should be able to provide proper guidance as to how to properly evaluate one's immune system. ...Read more
See details: That level is not extremely high, but why was the test ordered in the first place? You need to direct your question to the doctor who ordered the test in the first place. ...Read more