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Doctor insights on: Immunofixation Electrophoresis Procedure

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What is an immunofixation electrophoresis?

What is an immunofixation electrophoresis?

Blood test: This is a blood test it takes to look to see if you have a lot of the same antibodies in your blood. It can be useful in diagnosing multiple myeloma and waldendenstroms. Among other diseases. ...Read more

Electrophoresis (Definition)

Elecrophoresis is a process of running an electrical current through a matrix and separating items based on how fast they move through the matrix. Frequently in science and medicine, proteins or dna/rna is separated on gel based on the ...Read more


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What is the immunofixation electrophoresis?

What is the immunofixation electrophoresis?

Test for abnormal Ig: It is a test to characterize the nature of abnormal/monoclonal immunoglobulins in serum. It is often used in the diagnosis of multiple myeloma. ...Read more

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What is immunofixation electrophoresis? What is it used for?

What is immunofixation electrophoresis? What is it used for?

Immunofixation electrophoresis: This procedure identifies which kinds of antibodies are present and in what relative quantities, after they have been separated by moving in a gel exposed to an electric field. The gel supports the proteins and allows movement, which the size and type of charge on the antibody determines its rate of travel. ...Read more

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Doesn't immunofixation test for the same things as protein electrophoresis and even more than protein electrophoresis?

Doesn't immunofixation test for the same things as protein electrophoresis and even more than protein electrophoresis?

It is not same test: Serum protein electrophoresis (spe) is a screening test for myeloma and other paraproteinemias it simple shows the abnormal (m) protein peak.
Immunofixation is the next best test which provides a lot more additional information like the type of immunoglobulin which is causing the m spike and it will also tell us more useful info about further quantitation of the m peak and subtyping of your disease. ...Read more

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Will the serum protein electrophoresis test tell me anything that the immunofixation test would not tell me?

Will the serum protein electrophoresis test tell me anything that the immunofixation test would not tell me?

Yes.: The ife is very sensitive at finding an abnormal antibody (monoclonal antibody) in blood, but it does not measure the quantity. The spep is less sensitive at finding the monocloprotein protein, but it is a quantitative test, so it answers "how much" monoclonal protein is present. The spep is used to monitor therapy for that reason. ...Read more

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Slightly elevated beta fraction from serum protein electrophoresis. Beta 1.07 (high) (0.52-0.98) increased beta fraction, no monoclonal or polyclonal gammopathy seen. Immunofixation normal.

This report is of no: These values are of no particular concern. This test is mainly useful to check for monoclonal peaks...Which you do not have. ...Read more

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High KAPPA/LAMBDA LIGHT CHAIN/slightly high ratio. No Monoclonal protein immunofixation or serum electrophoresis. Is this a type of cancer? Normal WBC

High KAPPA/LAMBDA LIGHT CHAIN/slightly high ratio. No Monoclonal protein immunofixation or serum electrophoresis. Is this a type of cancer? Normal WBC

I bet it's nothing: Without free light chains or a monoclonal protein in blood or urine, the ratio's meaningless. And like most lab tests, the reference range is set so that a few percent of healthies fall outside on either end. ...Read more

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Serum free light chain test shows normal kappa (8.7mg/dl), low lambda (3.80), high kap/lam ratio (2.31). Serum $ urine electrophoresis show no monoclonal protein, nor does serum immunofixation. Likely MGUS, myeloma, or admyloidosis? CBC/met panel ok.

Serum free light chain test shows normal kappa (8.7mg/dl), low lambda (3.80), high kap/lam ratio (2.31). Serum $ urine electrophoresis show no monoclonal protein, nor does serum immunofixation. Likely MGUS, myeloma, or admyloidosis? CBC/met panel ok.

False positive rate: There is 30% or so false positive rate of kappa/lambda ratio in people without MGUS, myeloma or other disorders.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex. ...Read more

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My 4 months babies electrophoresis report is hb a2=2.4, hb a=4.2, hb f=68.4, hb e=25.How much severe?

My 4 months babies electrophoresis report is hb a2=2.4, hb a=4.2, hb f=68.4, hb e=25.How much severe?

NEED CONSULT HEMATOL: You to consult a pediatric hematologist about the above blood test as it suggest the baby may have e/beta thalassemia which is a genetic condition more common in suouth east asia
it can be mild condition with normal hemoglobin 9to12 grm/dl
or severe with hemoglobin 6to8grm/dl
please discuss with his pediatrician and consult a pediatric hematologist and you and your husband needs to tested as well. ...Read more

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My 4 months babies electrophoresis report is hb a2=2.4, hb a=4.2, hb f=68.4, hb e=25. Is iron based foods harmful for her?

My 4 months babies electrophoresis report is hb a2=2.4, hb a=4.2, hb f=68.4, hb e=25. Is iron based foods harmful for her?

Possibly: As I indicated in my previous post to you, your child has hemoglobin e / beta+ thalassemia. Some patients like your child will have problems with iron overload, even if they are not chronically transfused. For those patients, excess iron in the diet can be harmful. Please see a doctor with knowledge about hemoglobin e / beta+ thalassemia. ...Read more

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Could you tell me what electrophoresis means?

Electrophoresis: Electrophoresis: separates molecules by size & electric charge. ...Read more

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What is the definition or description of: electrophoresis?

What is the definition or description of: electrophoresis?

Separate things: Elecrophoresis is a process of running an electrical current through a matrix and separating items based on how fast they move through the matrix. Frequently in science and medicine, proteins or dna/rna is separated on gel based on the size of the proteins/dna/rna. ...Read more

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What to do if I am having trouble finding this question. Can all abnormal hemoglobin be diagnosed by electrophoresis?

No: Some may require more detailed analysis including DNA sequencing. Electrophoresis can detect most of the common and injurious variants. ...Read more

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What is d trait in hb electrophoresis report?

What is d trait in hb electrophoresis report?

A variant of normal: Hemoglobin d is a variant of normal hemoglobin. Is in unlikely to cause any significant problems but may be associated with mild anemia. You should discuss specifics about this with your physician. ...Read more

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My 4 months babies electrophoresis report hb a2=2.4, hb a=4.2, hb f=68.4, hb e=25.What type of medicine she needs? Please advice. Is it will be improve?

Hgb E/beta+thal: The child's electrophoresis report indicates the genetic and permanent condition known as hemoglobin e/beta+ thalassemia. The effects of this genetic condition are highly variable. Some children do relatively well, with rare transfusions; others are transfusion dependent. Problems with iron overload occur in some of these patients. Your child needs to see a pediatric hematologist for further care. ...Read more

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What is a hemoglobin electrophoresis?

Blood test: The idea is to separate the different hemoglobins in an electric field...They different ones migrate at different rates. So some of the composition of your blood is seen. ...Read more

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What are normal hemoglobin electrophoresis?

Values are: Hemoglobin f is present at birth and is replaced later with hemoglobin a and very small amount is made after birth
hemoglobin a1 96.5-98% of total hemoglobin
hg a2 1.5to3.5%of total hgb
hemoglobin 0to1%of total hemoglobin
no abnormal hemoglobin is present normally. ...Read more

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What does an abnormal protein band 1 mean on electrophoresis?

What does an abnormal protein band 1 mean on electrophoresis?

Bone marrow disorder: It means that you are making too much of a single antibody or just a part of an antibody because one clone of plasma cells from your bone marrow has developed over the normal population. This can be a benign condition for many years or progress into a condition called multiple myeloma that needs treatment. ...Read more

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What is the clinical applications of gel electrophoresis technique?

Gel electrophoresis: Separates gene digests for example so you can tell which gene it is.

It separates compounds based on size and electrical charge. If you want to chat I can give more details. ...Read more

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Hi I want to ask a question my report result say I have a condition anisocytosis and report suggests hb electrophoresis?

Hb electrophoresis: This test may be requested if there is a need to evaluate a patient for abnormalities of the hemoglobin molecule. If found, it can shed light on the cause of your abnormal blood report. ...Read more

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My babies blood electrophoresis report is hb a2=2.4, hb a=4.2, hb f=68.4, hb e=25. What's her physical condition? Please advice.

My babies blood electrophoresis report is hb a2=2.4, hb a=4.2, hb f=68.4, hb e=25. What's her physical condition? Please advice.

NEED CONSULT HEMATOL: You to consult a pediatric hematologist about the above blood test as it suggest the baby may have e/beta thalassemia which is a genetic condition more common in suouth east asia
it can be mild condition with normal hemoglobin 9to12 grm/dl
or severe with hemoglobin 6to8grm/dl
please discuss with his pediatrician and consult a pediatric hematologist and you and your husband needs to tested as well. ...Read more

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Sex: f, age: 2 yrs, hb electrophoresis report: hb a 0.5%, hb f 66.6%, hb e 30.3%, hb e2 2.6%. How much she is in danger? Her hemoglobin is 9.2.

Sex: f, age: 2 yrs, hb electrophoresis report: hb a 0.5%, hb f 66.6%, hb e 30.3%, hb e2 2.6%. How much she is in danger? Her hemoglobin is 9.2.

Hemoglobin EE: This is good news. Junior seems able to make plenty of Hemoglobin F and from my reading this is good news. Very glad a savvy physician started her on folic acid; a trial of Hydroxyurea is the only way to know if this will be helpful. She may have trouble keeping up in endurance sports but with a savvy parent like yourself, she should have a nice, happy, basically healthy life. ...Read more

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Why is hemoglobin hplc/ electrophoresis, blood done?

Variant hemoglobins: These tests are done to detect variants of hemoglobin as some of the variants, such as hemoglobin s, cause medical problems. Some states require all pregnant women be tested for hemoglobin variations as part of the antenatal care. ...Read more

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I did a hemoglobin electrophoresis test. The result negative and hemoglobin pattern are normal. What does this mean? I am not thalassemia carrirer?

Need more info: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, it would have helped to have the actual results, especially concentration of Hb A2. It would be prudent to discuss it with the doctor who ordered the tests.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex, if you have sex. ...Read more

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Are Lipoprotein Particle Size and Lipoprotein Electrophoresis test the same? I asked my Dr for Lipo Particle Size and Lp (a) but got Electrophor result

No: I don't think so. I think you need to use different technology to determine particle size. I believe the electrophoresis is only going to give LDL, HDL and VLDL concentration. You could check with the lab your doctor has sent you to to confirm this. ...Read more

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Electrophoresis : albumine 49 (normal 56-66%). Gamma 24 (normal 11-19). Ves 24 (normal < 15), CRP 5 (normal 0-0, 5). Is it all fault of obesity?

Electrophoresis : albumine 49 (normal 56-66%). Gamma 24 (normal 11-19). Ves 24 (normal < 15), CRP 5 (normal 0-0, 5). Is it all fault of obesity?

Probably more: This low an Albumin with what I will assume at your age is a polyclonal gammopathy makes me concerned about serious systemic disease or severe liver disease. Your obesity may have given you non-alcoholic steatohepatitis or you may have something else badly wrong. If your personal physician is not able to diagnose / explain, please ask for a consultation. ...Read more

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Can hemoglobin electrophoresis detect lupus?

Can hemoglobin electrophoresis detect lupus?

No.: Absolutely not. While both a clinical and lab diagnosis, lupus is not diagnosed with that test by any stretch! ...Read more