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Doctor insights on: Immunofixation Csf

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LP Done. Monocytes 1%, Serum IgG 587/mg/DL,Albumin 4100ml,IGG Index 1.1mg,WBC 23/mm3,RBC 1/mm3, CSF IGG 3.6 mg/DL,Lymphocytoid 97%, protein, neutrophils, glucose, CSF albumin all norm. Any ideas?

LP Done. Monocytes 1%, Serum IgG 587/mg/DL,Albumin 4100ml,IGG Index 1.1mg,WBC 23/mm3,RBC 1/mm3, CSF IGG 3.6 mg/DL,Lymphocytoid 97%, protein, neutrophils, glucose, CSF albumin all norm. Any ideas?

CSF Results: If I am reading the results correctly, there appears to be a mononuclear pleocytosis with normal protein, glucose and essentially normal immune response. The fluid analysis cn be seen in many disorders including viral meningitis. Need additional information. ...Read more

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Cerebrospinal Fluid (Definition)

The fluid that bathes the brain and spinal cord provides an exchange pathway and balancing system for brain and spinal cord metabolism, besides a cushioning system for routine impacts of our ...Read more


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What are the symptoms for csf?

What are the symptoms for csf?

CSF: CSF is fluid around your brain and spinal cord. What do you really want to ask? ...Read more

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2.8 oligoclonal bands IgG in CSF. Zero serum bands in CSF. Why does Mayo Clinic standards require 4 oligoclonal IGg CSF for MS diagnosis?

Other causes: Oligoclonal bands can be present in some other conditions such as infections and inflammation of the central nervous system. Increasing the threshold for diagnosing MS by requiring at least 4 oligoclonal bands, allows to exclude these other causes and diagnose MS with greater certainty. ...Read more

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What exactly is CSF rhinorrhea?

What exactly is CSF rhinorrhea?

A leaky brain : A CSF rhinorrhea occurs if there is an opening of the brain covering (dura) & the thin bone separating the nose from the base of the brain. This allows the sppinal fluid to leak into the nose.It is significant in revealing an open portal for nasal germs to get into the opening and cause repeated episodes of meningitis. ...Read more

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IgA lambda monoclonal gammopathy meaning?

IgA lambda monoclonal gammopathy meaning?

It is a medical diso: A medical disorder where your body is making excess of proteins(Gamma Globulins). It can manifest in 2-3 different ways(MGUS or Multiple Myeloma). So you need your doctor to explain which of these conditions do you have and theen get further testing, monitoring and you may or may not need treatment depending on whether it is mGUS(early) or Myeloma(later developemnt...that is a type of Blood Cancer ...Read more

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What causes low csf glucose, high csf monocytes ?

What causes low csf glucose, high csf monocytes ?

TB: This is not a suitable topic for this forum, as a proper diagnosis would require a whole lot additional information. TB meningitis can produce this picture. See this site for more info. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335590/ ...Read more

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What is IgA kappa monoclonal protein?

What is IgA kappa monoclonal protein?

IgA paraprotein: An IgA kappa monoclonal protein represents a single clone of bone marrow cells that have reproduced in an aberrant fashion. If this is what is found on immunofixation then a hematologist should be consulted for further workup. ...Read more

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Immunofixation, Serum FAH = Monoclonal IgG kappa immunoglobulin. Beta FAH = 10.5% Abnormal band, immunofixation to follow. I'm IgA deficient too. ??

Immunofixation, Serum FAH = Monoclonal IgG kappa immunoglobulin.   Beta FAH = 10.5% Abnormal band, immunofixation to follow. I'm IgA deficient too. ??

Possibly: If I am understaning this right you have a monoclonal protien band? The most important next steps here would be to identify the band (immunofixation) and then perfrom quantitvaive immunoglobulin levels. IF there is a monoclonal band, you may very well have reciprocal depriciation of alternative immunoglobulins and IgA deficiecny with an IgG monoclonal protein is possible. ...Read more

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Igg synthesis (csf +serum) 20.1, IgG index 1.86, albumin CSF 11.8 , IgG CSF 6.4 , IgG 1080 , albumin 3.7, protein 34 and glucose 54 what do they mean?

Igg synthesis (csf +serum) 20.1, IgG index 1.86, albumin CSF 11.8 , IgG CSF 6.4 , IgG 1080 , albumin 3.7, protein  34 and glucose 54 what do they mean?

Lab Values: These are results from CSF (cerebral spinal fluid) tests that identify values that tell your physician whether you have normal or abnormal levels of Immune Globulin (igg), whether the ratio compared to your blood is correct; adequate protein(albumin) and sugar in the csf. All of these help to diagnose what type of problem may be occurring in your body and nervous system especially. ...Read more

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Lumbar puncture results: Multiple IgG oligoclonal bands detected in CSF and serum, most bands unique to CSF. IgG value 9.43, range 6 - 15 Is this MS?

Consistent: But diagnosis of MS should be based on history, physical exam, results of MRI films, and spinal fluid is useful in ambiguous cases. However, elevation of oligoclonal bands can be seen in several disorders and NOT definitive on its own. Have your doctor now put the whole picture in place. Most likely MS, but other possibilities exist. ...Read more

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Pl tell me homeopathic medicine for CSF rhinorrhoea?

Csf: If you have CSF rhinorrhea you should see a neurosurgeon or specializzed ENT asap. No homeopathic medicine helps this. ...Read more

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What does high IgG kappa monoclonal protein in blood mean?

What does high IgG kappa monoclonal protein in blood mean?

See a specialist: You don't tell me how you were found to have that high level. If you have no symptoms to go with that finding and other laboratory blood tests are normal, you probably have what is called monoclonal gammopathy. If you have symptoms or tests are affected, there are several possible diagnosis. For proper evaluation, see an immunologist or hematologist. ...Read more

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Adnorm. Blood & cfs results: high: CSF protein-47, high cfs albumin-30.9; low total protein-5.7, low gamma globulin-.5, low IgG quantitative -621 worry?

Adnorm. Blood & cfs results: high: CSF protein-47, high cfs albumin-30.9; low total protein-5.7, low gamma globulin-.5, low IgG quantitative -621 worry?

CSF: Some experts consider CSF protein levels to be normal if the value is equal to or below your age in years. I don't think in your case there is a reason to worry. Other CSF components are important as well. Check with your physician to see if there is any reasons to worry. Hope you feel well soon. ...Read more

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Could you provide some information on dealing with CSF leakage?

See below: CSF leak may occur after a spinal tap. Rarely there can be a spontaneous CSF leak. It is usually associated with severe headache. See this site for more info. http://www.nlm.nih.gov/medlineplus/ency/article/001068.htm ...Read more

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Are IgG lambda monoclonal bands common?

IgG lambda rare: Only 20% of all human igg use lambda light chains. Monoclonal bands are not common in general and may be benign or a sign of myeloma. Most a kappa. ...Read more

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What is monoclonal gammopathie IgM kappa?

What is monoclonal gammopathie IgM kappa?

Plasma cell disorder: Monoclonal gammopathy refers to an abnormal production of proteins by cells in the immune system (plasma cells) that are growing out of control. It can be one of the signs of myeloma. A hematologist-oncologist can help. ...Read more

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Serum free light chain test shows normal kappa (8.7mg/dl), low lambda (3.80), high kap/lam ratio (2.31). Serum $ urine electrophoresis show no monoclonal protein, nor does serum immunofixation. Likely MGUS, myeloma, or admyloidosis? CBC/met panel ok.

Serum free light chain test shows normal kappa (8.7mg/dl), low lambda (3.80), high kap/lam ratio (2.31). Serum $ urine electrophoresis show no monoclonal protein, nor does serum immunofixation. Likely MGUS, myeloma, or admyloidosis? CBC/met panel ok.

False positive rate: There is 30% or so false positive rate of kappa/lambda ratio in people without MGUS, myeloma or other disorders. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more

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What does quantitative igg subclass measurement blood test show?

What does quantitative igg subclass measurement blood test show?

IgG subclasses: There are several classes of immunoglobulins like IgA, IgM, and IgE. IgG also has subclasses that we test for. A subclass deficiency can be an explanation for susceptibility to certain types of infections. An Allergist/Immunologist can put the results in perspective for you in the context of your history. ...Read more

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In protein's electrophoresis Is polyclonal gammopathy alway pathological? Thanks

Need more info: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, What is total gamma globulin level? If it is more than 2.0 gm/dL it needs to be evaluated. There are many causes of polyclonal gammopathy., and some of those are serious. ...Read more

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In CSF Volume=2.5mL total protein=119mg/dl Appearnce=Clear Suger=55mg/dl Cell count=5mm3 Rbcs=5mm3 Lymphocytes=100% Neutrophils=0% Is it GBS ?

In CSF Volume=2.5mL
total protein=119mg/dl
Appearnce=Clear
Suger=55mg/dl
Cell count=5mm3
Rbcs=5mm3
Lymphocytes=100%
Neutrophils=0%
Is it GBS ?

Possibly: Without knowing symptoms and history difficult to say for sure but the elevated protein with relatively normal cell count is something encountered in GBS. ...Read more

Csf (Definition)

Cerebrospinal fluid is the clear colorless fluid produced in the choroid plexus in the brain, and acts as a cushion or a buffer for the ...Read more