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Doctor insights on: Immunofixation And Immunoglobulins

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Does raised immunoglobulin m (igm) mean I have some disease?

Does raised immunoglobulin m (igm) mean I have some disease?

High IgM: This is typically normal if seen on any one spot check. If it is high repeatedly on two or more checks, a test called " immunofixation" should be ordered to be sure it is not coming from only one population of blood cells; rarely, this could be due to a monoclonal gammopathy (a pre-cancerous condition). Or even rarer, a blood cell cancer called multiple myeloma. ...Read more

Immunoglobulin (Definition)

Immunoglobulins are antibodies produced by b cells. They have a y shaped configuration. They are involved in protecting us ...Read more


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Can anyone experienced with ivig (intravenous immunoglobulin) describe what one should expect?

General well tolerat: Ivig is a blood product that, in allergy, is used to treat those with immunodeficiency or a lack of igg ( that is the IG part of ivig). This is generally a well tolerated infusion but one can experience local discomfort from the insertion of the needle to infuse the ivig. Rarely, systemic reactions can occur including headache, nausea, hives and others. ...Read more

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Can you tell me about immunoglobulins: help me for biology?

See Below: Immunoglobulins are a type of protein made by your body to help protect it against infections. There are five types of immunoglobulins: IgA, IgD, IgE, IgG, and IgM. Each of these has a slightly different function in infection fitting. ...Read more

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What does low immunoglobulin g subclass 2 on blood work mean?

What  does low immunoglobulin g subclass 2 on blood work mean?

Low gamma globulin: By itself, a slightly low level of one igg subclass is a very nonspecific finding. A very low level would be worrisome, but really, what is needed is to look at this information in the context of vaccine responses to Pneumovax vaccine. If the functional antibodies made by the immune system are at normal levels, the gross levels of antibody are less worrisome. ...Read more

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Is it safe to take rabies immune globulin while pregnant or breastfeeding?

Is it safe to take rabies immune globulin while pregnant or breastfeeding?

Yes, IgG is safe: Immune globulin (igg) is concentrated antibodies, and helps protect against a variety of infections. It is safe for pregnant women, breastfeeding moms, and infants. Of course, there could be a rare allergic reaction on a rare occassion. Because IgG is purified from other people's blood plasma, there is also a very, very rare chance that something contagious could be transmitted in the injection. ...Read more

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Does intravenous immunoglobulin (ivig) infusions benefit someone with IgG defiency?

Possibly: If you are deficient and symptomatic (recurrent infections), they can possibly help your body fight infections better. Just because you have an igg deficiency does not mean your are immune deficient, however. Many people with low numbers have normal function and really are asymptomatic. ...Read more

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Is it possible for low immunoglobulin g (igg) to cause joint pain?

Is it possible for low immunoglobulin g (igg) to cause joint pain?

Yes: It depends on the type of deficiency (IgG subtype or total) and the level. You should see an immunologist or a rheumatologist with specific training in this area for evaluation ...Read more

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I just rec'd more bloodwork results. Immunoglobulin g subclass is low & lymphocytes absolute is low, what does it mean?

I just rec'd more bloodwork results. Immunoglobulin g subclass is low & lymphocytes absolute is low, what does it mean?

Deoends: Having one low igg subclass does not mean you have a problem. See a board- certified allergist (take your lab) and they can help you. ...Read more

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Elevated immunoglobulin a means what?

Different things: Immunoglobulin could be elevated in many different conditions such as infections, inflammation , other chronic diseases as well as certain blood malignancies. My suggestion is to go to see your pmd and discuss further with your doc. If the level is significantly high or if it is suspicious then your doc can refer you to see a specialist- a hematologist/oncologist for further investigation. ...Read more

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What does a high immunoglobulin mean ?

How high?: Minimally elevated probably not worth worrying about. Very or moderately high requires a test - serum immunoelectrophoresis - to rule-out multiple myeloma. Minimally high bears repeating twice a year. ...Read more