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Doctor insights on: Igm Nephropathy

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IgA lambda monoclonal gammopathy meaning?

IgA lambda monoclonal gammopathy meaning?

It is a medical diso: A medical disorder where your body is making excess of proteins(Gamma Globulins). It can manifest in 2-3 different ways(MGUS or Multiple Myeloma). So you need your doctor to explain which of these conditions do you have and theen get further testing, monitoring and you may or may not need treatment depending on whether it is mGUS(early) or Myeloma(later developemnt...that is a type of Blood Cancer ...Read more

Dr. William Singer
104 doctors shared insights

Nephropathy (Definition)

Nephropathy is a medical term that refers to disease of the kidney. There are many causes. It can be caused by high blood pressure, diabetes, uric acid, abnormal proteins, cancers, blood vessel blockages in the kidney, it can be minimal or or it can be severe ...Read more


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Is IGA Nephropathy genetic/hereditary?

Is IGA Nephropathy genetic/hereditary?

IgA neph: Data have shown a genetic clustering for IgA nephropathy - however its genetic nature is not certain - ...Read more

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Ebvab VCA IgM <36 (range 0-35.9), ebvearly antigenab IgG 37 (0-8.9), ebvab VCA IgG >600 (0-17.9), EBV nuclearantigenab IgG 409 (0-17.9) mono? No mono?

Ebvab VCA IgM <36 (range 0-35.9), ebvearly antigenab IgG 37 (0-8.9), ebvab VCA IgG >600 (0-17.9), EBV nuclearantigenab IgG 409 (0-17.9) mono? No mono?

You had mono...: Your mono-like symptoms likely prompted the testing- i hope you are starting to feel a little better. Testing for different antibodies (igm and igg) against ebv, requires careful interpretation. In early phases of infection, the igm level peaks first followed by a decline; levels of igg peak afterwards, and may remain elevated for quite a while. ...Read more

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Recurring fever with 2g proteinuria with 1.1-2.2 serum creat. ebv b19 cmv igg positive/elevated. Neph says igg means no current infection. Workup?

Recurring fever with 2g proteinuria  with 1.1-2.2 serum creat. ebv b19 cmv igg positive/elevated.  Neph says igg means no current infection. Workup?

Still ask your doc: Since you have come this far in evaluation and care, it would be most logical and beneficial for you to bring all of your concerns and questions to your doctors since they would know your individual conditions more than anyone online. More online sporadic inquiry at this time may induce more unnecessary anxiety and fear. ...Read more

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What is monoclonal gammopathie IgM kappa?

What is monoclonal gammopathie IgM kappa?

Plasma cell disorder: Monoclonal gammopathy refers to an abnormal production of proteins by cells in the immune system (plasma cells) that are growing out of control. It can be one of the signs of myeloma. A hematologist-oncologist can help. ...Read more

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Cardiolipin antibodies IgM and urine protein 72mg/l ? Ana negative.

Cardiolipin antibodies IgM and urine protein 72mg/l ? Ana negative.

See details: The urine protein is within normal limits. How strongly positive is the igm cardiolipin. Only high levels of positivity have any clinical significance. Why were the tests ordered in the first place? ...Read more

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What is IgA kappa monoclonal protein?

What is IgA kappa monoclonal protein?

IgA paraprotein: An IgA kappa monoclonal protein represents a single clone of bone marrow cells that have reproduced in an aberrant fashion. If this is what is found on immunofixation then a hematologist should be consulted for further workup. ...Read more

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Ebv panel. Ebv nuc antigen igg=157, early ag igg=12.7, EBV VCA igg=112, EBV VCA igm=10.6. Please explain. Concerned about spleen. Symp=fatigue/fog?

Ebv panel. Ebv nuc antigen  igg=157, early ag igg=12.7, EBV VCA igg=112, EBV VCA igm=10.6.  Please explain.  Concerned about spleen. Symp=fatigue/fog?

? Active infection: It's impossible for me to answer with certainty since i don't know the normal ranges your lab uses. If early ag & vca igm are elevated above normal this indicates active ebv infection.I don't know if it is acute or chronic without knowing your history. If chronic i see that as a sign of poor immune function.Immune-boosting herbs/supplements & IV vit c drips may help, but find why immunity is poor. ...Read more

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LP Done. Monocytes 1%, Serum IgG 587/mg/DL,Albumin 4100ml,IGG Index 1.1mg,WBC 23/mm3,RBC 1/mm3, CSF IGG 3.6 mg/DL,Lymphocytoid 97%, protein, neutrophils, glucose, CSF albumin all norm. Any ideas?

LP Done. Monocytes 1%, Serum IgG 587/mg/DL,Albumin 4100ml,IGG Index 1.1mg,WBC 23/mm3,RBC 1/mm3, CSF IGG 3.6 mg/DL,Lymphocytoid 97%, protein, neutrophils, glucose, CSF albumin all norm. Any ideas?

CSF Results: If I am reading the results correctly, there appears to be a mononuclear pleocytosis with normal protein, glucose and essentially normal immune response. The fluid analysis cn be seen in many disorders including viral meningitis. Need additional information. ...Read more

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My serum test is negative for endomysial antibody iga, ttg tissue transglutasminase iga, gliadin antibody igg. But positive for gliadin antibody iga?

My serum test is negative for endomysial antibody  iga, ttg tissue transglutasminase iga, gliadin antibody igg. But positive for gliadin  antibody iga?

Treat the person: Lab tests mean nothing in isolation, and have many false positives and false negatives. The decision to make a trial of a gluten-free diet will be between you and your gastroenterologist or dermatologist based on the big picture. ...Read more

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Elevated EBV ab VCA IgG <8 and EBV nucleaer antigen ab IgG test 4.2. & anti-dna(ss)igg ab qn ( 119)& c react protien(5.6) what are implications?

Elevated EBV ab VCA IgG <8 and EBV nucleaer antigen  ab IgG test 4.2. & anti-dna(ss)igg ab qn ( 119)& c react protien(5.6)  what are implications?

Nothing.: Ebv antibodies indicate you had a previous infection, but not active. The c-reactive protein needs a units indicator - that is either normal or somewhat elevated. The anti ss dna is extremely nonspecific and very rarely indicated; I have no idea why that was ordered, discuss with your doctor. ...Read more

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Immunofixation, Serum FAH = Monoclonal IgG kappa immunoglobulin. Beta FAH = 10.5% Abnormal band, immunofixation to follow. I'm IgA deficient too. ??

Immunofixation, Serum FAH = Monoclonal IgG kappa immunoglobulin.   Beta FAH = 10.5% Abnormal band, immunofixation to follow. I'm IgA deficient too. ??

Possibly: If I am understaning this right you have a monoclonal protien band? The most important next steps here would be to identify the band (immunofixation) and then perfrom quantitvaive immunoglobulin levels. IF there is a monoclonal band, you may very well have reciprocal depriciation of alternative immunoglobulins and IgA deficiecny with an IgG monoclonal protein is possible. ...Read more

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ANA 1:80 speckled, SM, RNP, SCL-70 detected.Leukocyte, urate, alkaline phosphate,creatinine low. Albumin, triglycerides high. Pos HAV, HBV. Rhem. Neg?

ANA 1:80 speckled, SM, RNP, SCL-70 detected.Leukocyte, urate, alkaline phosphate,creatinine low. Albumin, triglycerides high. Pos HAV, HBV. Rhem. Neg?

Not enough info: Lab tests need to be evaluated in the context of the clinical symptoms. You need this issue evaluated by a rheumatologist ...Read more

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What does high anti EBV VCA IgA means?

Not much: It just means that you have been exposed (or infected) to EBV at an indeterminate time. ...Read more

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Reactivated EBV 9 months after first infection. Could i be immunodeficient? Antibody count: 65 ab VCA igm; 53 ea ab igg; 431 ab VCA igg; 289 ebna igg.

No: Unfortunately ebv stays alive forever in one's lymphocytes and can get activated easily in susceptible people without known immunodeficiency. However you may call that an immunodeficiency given that all people have been infected with it yet only few would have recurrent ebv problem. ...Read more

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Do elevated gliadin antibodies IgG and IgA mean gluten sensitivity?

Do elevated gliadin antibodies IgG and IgA mean gluten sensitivity?

TTG: I woul recommend having a ttg IgA antibody and possible duodenal bx , in doing so a diagnosis of celiac disease can be made. If if asymptomatic, there may be benefit from a gluten free diet especially if small bowel inflammation noted. ...Read more

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What does a high EBV viral capsid antibody IgM mean?

What does a high EBV viral capsid antibody IgM mean?

DIAGNOSIS IS MONO:: Acute phase of infectious mononucleosis is characterized by rapid igm and igg antibody response to viral capsid antibody(vca) in all patients. The test may remain positive from 4 weeks, occasionally up to 4 months. ...Read more

Dr. Gregory Lanza
821 doctors shared insights

Immunoglobulin M (Definition)

There are 5 classes of immune proteins: igg, iga, igm, ige and igd. Igm fights infection. If you produce too little then infections may occur and you have hypogammaglobulinemia. If you have too much you ...Read more


Dr. Tarek Naguib
2,396 doctors shared insights