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Doctor insights on: Igm Antibodies Equivocal For Lyme Disease

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Tested positive for Lyme disease IgM but my western blot test came back negtive?

Tested positive for Lyme disease IgM but my western blot test came back negtive?

Then it's not Lyme: Lyme disease can be tricky -and you want to make sure you see someone like an Infectious Diseases doctor who knows how to treat it. The diagnosis is actually based on clinical findings, and the lab testing is generally 'supportive'. Since you're Western blot is negative, then it's very unlikely you have Lyme. There are other diseases that could cause 'Lyme-like' symptoms -and good to get evaluated ...Read more

Dr. Randy Baker
639 doctors shared insights

Lyme Disease (Definition)

A condition caused by borrelia burgdorferi. Acute symptoms can include bullseye rash, headaches, joint pain, fever, and flu-like sx. Chronic symptoms can include fibromyalgia symptoms, nerve pain in extremities, mood swings, brain fog, heart problems. Lab diagnoses are not very reliable, and sometimes clinical ...Read more


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How long could the IgG in Lyme disease stay positive?Could it stay positive more than 5-10 years? I know the IgM ab convert to IgG just want an answer

How long could the IgG in Lyme disease stay positive?Could it stay positive more than 5-10 years? I know the IgM ab convert to IgG just want an answer

Yes,positive 20+ yrs: Research suggests igg antibodies can persist at least 20 years after infection. While igm antibodies appear first, unlike other infections they often persist ; are a good indicator of persistent infection. One may have chronic lyme with or without persistence of igg antibodies. Chronic lyme is difficult to fully eradicate ; no current test proves that it is no longer present in your body! ...Read more

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Could i have Lyme disease? Not posible its recent. Borrelia Oct 14 IgM = 1.00 (1-1.5 inconclusive), Jan 15 IgM = 1.53 (1.5+pos) IgG = 0.16 (<1.00neg)

Could i have Lyme disease? Not posible its recent. Borrelia  Oct 14 IgM = 1.00 (1-1.5 inconclusive), Jan 15 IgM = 1.53 (1.5+pos) IgG = 0.16 (<1.00neg)

See details: The lab results sre unimpressive. I strongly doubt Lyme disease based on your lab results. Without your symptoms and results of a Western blot it is impossible to answer. I ...Read more

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Was test for Lyme disease and test seem to be normal except for igm is 1.32 high and igm p23 present all else says absent, does this mean I have Lyme?

Infected yes: Elevated IgM points to recent or current infection. Whether you do have Lyme Disease or not will need further observation. For example, have you seen any target like lesion yet? ...Read more

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I tested positive for Lyme disease. I was given the EIA (result 6.1), IgG (10 bands present) and IgM WB (3 bands) Does this mean I've had LD for a whi?

I tested positive for Lyme disease. I was given the EIA (result 6.1), IgG (10 bands present) and IgM WB (3 bands) Does this mean I've had LD for a whi?

Yes: The presence of IgG usually indicates past infection which might have occurred months or even years ago. The presence of IgM indicates a current or recent infection. ...Read more

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Igm is negative but IgG is positive for Lyme disease, what to do?

Igm is negative but IgG is positive for Lyme disease, what to do?

Old Infection: This most likely means you had an old infection with lyme disease. Our bodies make IgM early in an infection and IgG later. Even once the infection is gone there will be detectable IgG for quite some time. This is part of how our body remembers previous infections so we can fight them off better if we get them again. ...Read more

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Why would my lyme disease western blot test show 4 igg bands as reactive? Could this mean I have the disease? None of the igm bands were reactive.

Why would my lyme disease western blot test show 4 igg bands as reactive? Could this mean I have the disease? None of the igm bands were reactive.

Not necessarily: IgM antibody means recent infection. IgG antibody usually means remote infection. You may not have the disease, just that you may have been infected at one time. ...Read more

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"p23 ab IgM reactive" "p41 & p39 non-reactive" do I have Lyme disease, or can something else cause this? (diagnosed w/ rheumatoid arthritis 7yrs ago.)

"p23 ab IgM reactive" "p41 & p39 non-reactive" do I have Lyme disease, or can something else cause this? (diagnosed w/ rheumatoid arthritis 7yrs ago.)

Complex: The diagnosis of lyme disease is usually on a clinical basis. Serologic testing should not be done for screening purposes. False positive results are very frequent in patients with autoimmune diseases, particularly rheumatoid arthritis, and particularly when these are IgM antibodies. ...Read more

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Lyme disease ab plus reflex to igg, igm-wb blood test done today. How long for results and how accurate are they?

About a week: The regular lyme test is specific but not very sensitive .There can be many reasons for a false positive result. If it is positive on the screening test it is then sent for the more sensitive western blot test. If the igm test is positive it could represent a recent exposure to lyme disease if the igg is positive it indicates a more distant orast exposure. If the igm is positive you should be eval. ...Read more

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Dr. Gregory Lanza
816 doctors shared insights

Immunoglobulin M (Definition)

There are 5 classes of immune proteins: igg, iga, igm, ige and igd. Igm fights infection. If you produce too little then infections may occur and you have hypogammaglobulinemia. If you have too much you ...Read more


Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more