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Doctor insights on: Igg Subclass Igg3

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My ch50 is 394 and normal range upper limit is 300. C3 and C4 are normal. Can you tell me what this means? My IgG subclass 2 serotypes are all low

My ch50 is 394 and normal range upper limit is 300.  C3 and C4 are normal.  Can you tell me what this means?  My IgG subclass 2 serotypes are all low

Ignore it: Ch50 is hard to do correctly, unless the value is way off i would ignore it, and it may just be up from a transient infection or be your normal. Unless your igg subclass is very low, i would ignore this as well. We pathologists say, "focus on the person, not the numbers." by the way, i attended lfhs and perhaps we know one another. ...Read more

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What to do if I have high neutrophilis, low lymphs & monocytes , high glucose and low IgG subclass 1 &3?

What to do if I have high neutrophilis, low lymphs & monocytes , high glucose and low IgG subclass 1 &3?

Talk with your Dr: Labs mean nothing in isolation. This is concerning and you have a right to talk with a specialist if need be -- an endocrinology and clinical immunology consult may be in order. ...Read more

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I have an IgG subclass 3 deficiency. What diseases/disorders are associated with this? Are you more likely to acquire certain diseases/disorders?

IgG3 subclass def: Igg has four types. Igg3 is involved in fighting against carbohydrate covered infectious organisms. Igg1 is the most numerous and igg3 is of much less quantity. If you have normal antibody titers to vaccines, then you are likely safe. I would simply monitor all of your immunoglobulin levels yearly. ...Read more

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Could IgG subclass deficiencies be caused by plasma b cell diseases/disorders?

Yes: It is possible to have malfunction of immunoglobulins or low levels in b cell disorders. A subclass deficiency by itself is usually not clinically significant and does not warrant treatment but if an underlying b cell disorder exists, it should be remedied. ...Read more

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What to do if I have high neutrophilis, low lymphs & monocytes , high glucose and low IgG subclass 1 &3?

Talk with your Dr: Labs mean nothing in isolation. This is concerning and you have a right to talk with a specialist if need be -- an endocrinology and clinical immunology consult may be in order. ...Read more

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Is there CSF IgG subclass deficiency? I have lowish IgG and IgG subclass deficiencies (1, 3, 4) and CSF IgG of 685 .

Csf labs: Lab values for cerebrospinal fluid tests must be interpreted in the context of the symptoms and signs and the time course, as well as imaging information. Your question cannot be answered in isolation. Please consult a neurologist. ...Read more

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What does quantitative igg subclass measurement blood test show?

What does quantitative igg subclass measurement blood test show?

IgG subclasses: There are several classes of immunoglobulins like IgA, IgM, and IgE. IgG also has subclasses that we test for. A subclass deficiency can be an explanation for susceptibility to certain types of infections. An Allergist/Immunologist can put the results in perspective for you in the context of your history. ...Read more

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If igg subclass tests were all normal range, does it mean my immune system is ok? Unclear on meaning of tests and what it represents as far as my body

If igg subclass tests were all normal range, does it mean my immune system is ok? Unclear on meaning of tests and what it represents as far as my body

IgG subclasses: Why tested for? Those are rather special tests done if there is a suspicion of subclass deficiency guided by history and physical examination, if they were fine, means generally your immune system is functional, but there are some subtleties that need to be checked if still suspecting an immune problem. Kindly ask your doctor or your allergist/Immunologist about the results/other tests needed ...Read more