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Doctor insights on: Igg Albumin Ratio Csf

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CSF IgG is 2.6, CSF Albumin is 28, CFS IgG/Albumin Ratio is 9%. Could this indicate MS or Lyme Disease if clinically the symptoms fit?

CSF IgG is 2.6, CSF Albumin is 28, CFS IgG/Albumin Ratio is 9%. Could this indicate MS or Lyme Disease if clinically the symptoms fit?

Test results: The IGG Index requires a comparison to the IGG in blood and CSF. It is a nonspecific test for inflammatory diseases like those you referred to. What were the blood levels? A better test for MS is CSF oligoclonal bands. Do you have that? Along with an MRI result? For Lyme disease you would want a CSF ELISA or Western blot for Lyme proteins. Hope that helps. ...Read more

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Dr. Raj Singh
254 doctors shared insights

Albumin (Definition)

Albumins are proteins which dissolve in water and are not covered with chains of sugars. The most common is serum albumin. These molecules transport other molecules which don't dissolve in water very well. But its main function is to regulate the amount of water in the blood. Another type of Albumin is the ...Read more


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Igg synthesis (csf +serum) 20.1, IgG index 1.86, albumin CSF 11.8 , IgG CSF 6.4 , IgG 1080 , albumin 3.7, protein 34 and glucose 54 what do they mean?

Igg synthesis (csf +serum) 20.1, IgG index 1.86, albumin CSF 11.8 , IgG CSF 6.4 , IgG 1080 , albumin 3.7, protein  34 and glucose 54 what do they mean?

Lab Values: These are results from CSF (cerebral spinal fluid) tests that identify values that tell your physician whether you have normal or abnormal levels of Immune Globulin (igg), whether the ratio compared to your blood is correct; adequate protein(albumin) and sugar in the csf. All of these help to diagnose what type of problem may be occurring in your body and nervous system especially. ...Read more

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Adnorm. Blood & cfs results: high: CSF protein-47, high cfs albumin-30.9; low total protein-5.7, low gamma globulin-.5, low IgG quantitative -621 worry?

Adnorm. Blood & cfs results: high: CSF protein-47, high cfs albumin-30.9; low total protein-5.7, low gamma globulin-.5, low IgG quantitative -621 worry?

CSF: Some experts consider CSF protein levels to be normal if the value is equal to or below your age in years. I don't think in your case there is a reason to worry. Other CSF components are important as well. Check with your physician to see if there is any reasons to worry. Hope you feel well soon. ...Read more

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LP Done. Monocytes 1%, Serum IgG 587/mg/DL,Albumin 4100ml,IGG Index 1.1mg,WBC 23/mm3,RBC 1/mm3, CSF IGG 3.6 mg/DL,Lymphocytoid 97%, protein, neutrophils, glucose, CSF albumin all norm. Any ideas?

LP Done. Monocytes 1%, Serum IgG 587/mg/DL,Albumin 4100ml,IGG Index 1.1mg,WBC 23/mm3,RBC 1/mm3, CSF IGG 3.6 mg/DL,Lymphocytoid 97%, protein, neutrophils, glucose, CSF albumin all norm. Any ideas?

CSF Results: If I am reading the results correctly, there appears to be a mononuclear pleocytosis with normal protein, glucose and essentially normal immune response. The fluid analysis cn be seen in many disorders including viral meningitis. Need additional information. ...Read more

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What causes high globulin, but low globulin albumin ratio?

Liver blood tests: The liver is an amazing organ- it does many things including making proteins your body needs. Albumin is a major protein product of the liver. Chronic illness can cause that to decline- esp. if you're not eating. Globulins are other proteins usually made to fight diseases like infections- perhaps you've been fighting an illness for a few weeks/months that explain this pattern. ...Read more

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Is there CSF IgG subclass deficiency? I have lowish IgG and IgG subclass deficiencies (1, 3, 4) and CSF IgG of 685 .

Is there CSF IgG subclass deficiency? 
I have lowish IgG and IgG subclass deficiencies (1, 3, 4)  and CSF IgG of 685 .

Csf labs: Lab values for cerebrospinal fluid tests must be interpreted in the context of the symptoms and signs and the time course, as well as imaging information. Your question cannot be answered in isolation. Please consult a neurologist. ...Read more

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I had a recent lp. What does slightly-below normal levels of IgG proteins in the CSF indicate?

I had a recent lp. What does slightly-below normal levels of IgG proteins in the CSF indicate?

Not of much concern: Why did you have an lp? Slightly low igg is not of much importance by itself. It would be prudent to the discus all of the results with your doctor as the context is important in interpreting lab results. ...Read more

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Had spinal tap. O bands were found in CSF and not blood sample. IgG Index, CSF was 1.20. Does this tell how many bands? Says MS or another disease?

Get diagnosed: The spinal fluid may well be consistent with an immune mediated disorder, but MS is a clinical diagnosis based on history, exam, and MRI patterns. Your neurologist should readily be able to sort out these findings. And no, you do not list the number of oligoclonal bands. ...Read more

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2.8 oligoclonal bands IgG in CSF. Zero serum bands in CSF. Why does Mayo Clinic standards require 4 oligoclonal IGg CSF for MS diagnosis?

2.8 oligoclonal bands IgG in CSF. Zero serum bands in CSF.  Why does Mayo Clinic standards require 4 oligoclonal IGg CSF for MS diagnosis?

Other causes: Oligoclonal bands can be present in some other conditions such as infections and inflammation of the central nervous system. Increasing the threshold for diagnosing MS by requiring at least 4 oligoclonal bands, allows to exclude these other causes and diagnose MS with greater certainty. ...Read more

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Lumbar puncture results: Multiple IgG oligoclonal bands detected in CSF and serum, most bands unique to CSF. IgG value 9.43, range 6 - 15 Is this MS?

Consistent: But diagnosis of MS should be based on history, physical exam, results of MRI films, and spinal fluid is useful in ambiguous cases. However, elevation of oligoclonal bands can be seen in several disorders and NOT definitive on its own. Have your doctor now put the whole picture in place. Most likely MS, but other possibilities exist. ...Read more

Cerebrospinal Fluid (Definition)

The fluid that bathes the brain and spinal cord provides an exchange pathway and balancing system for brain and spinal cord metabolism, besides a cushioning system for routine impacts of our ...Read more


Csf (Definition)

Cerebrospinal fluid is the clear colorless fluid produced in the choroid plexus in the brain, and acts as a cushion or a buffer for the ...Read more