Doctor insights on:
Igf 1 Somatomedin C
When igf-1 is shown as high at one lab so doctor runs test at other labs until normal result obtained, which is then relied on, are any of the results valid?
They aren't: There aren't any natural igf-1 supplements. Igf-1 is made in your body. It is also available by injection from a physician, not it is really in any supplement you can buy at the store or on the internet. Even if it were, it wouldn't work and would be broken down in you stomach. ...Read more
Growth: IGF-1 is one of the main "growth hormones" and is stimulated by pituitary growth hormone. During adolescence, the levels of IGF-1 are higher than at other times. A very high IGF-1 can occur due to acromegaly, which is a pituitary tumor making excess GH, but this is very rare. A pediatric endocrinologist is the expert on this. ...Read more
Don't waste money: The IGF-1 products sold in health stores and on the internet as anti-aging agents have not been clinical tested and are unlikely to have any real benefit so it probably makes no difference how you take them. My advice is not to waste you money on them but try eating healthier and getting more exercise ...Read more
Are you referring: To some sort of growth factor? Just not really certain what specific product this is in reference to. ...Read more
No GH excess: Hi. In our lab, that IGF-1 would be within normal limits for a 43 yo woman, so we have no evidence of growth hormone excess. However, the BMI is 36.4, diagnostic of obesity. The height is stated as "1.82 cm", but I strongly suspect you mean 1.82 m or 182 cm. This is taller than the average woman, but the IGF-1 suggests no GH excess. ...Read moreSee 1 more doctor answer
Probably not: The igf level is in the low normal range for age, and highly dependent upon time of day and other factors. Don't know why your doc would have been drawing an igf level at your age without having other abnormal lab prior to checking igf. Ask your doctor why. ...Read more
GH measurement: Gh levels fluctuate considerably throughout the day, often being high during the night, and very low other times of the day, which makes a single measurement unreliable. Igf1 is more stable. Adolescence is a time of many normal hormone fluctuations. There are diseases associated with very high gh/igf1 (eg. Acromegaly) but are rare. ...Read more
When igf-1 is high and gh are normal rule out the possibility of Acromegaly? Or get more complicated the Diagnosis?
Unlikely: Acromegaly as a result of excessive GH is extremely rare and symptoms are not straight forward but you can look them up. The IGF-1 is a good screening test for GH excess but if it was only mildly elevated the normal GH would be reassuring. After you read up, please discuss with the doctor who ordered the tests because it can be complicated ...Read more
Human vs synthesized: RhIGF-1 protein is synthetic, made in E. coli bacteria and sometimes yeast that have been modified in the lab to have the gene for human IGF-1, enabling them to produce IGF-1. Plain IGF-1 protein is endogenous, coming from humans, but this is not used nearly as much anymore as the rhIGF-1 (trade name is Increlex). ...Read more
Can IGF-1 be as effective as rhIGF-1 for height increase in children? And how is IGF-1 lr3 different from the two above?
Growth: IGF1 is the effector protein of growth hormone. rhIGF1 just means it is synthetic. IGR IR3 is an analog, which should work the same way. The most important question is why is this being given, and has the proper work-up been done. Is there GH or IGF1 deficiency? If not, is this just being done to (maybe) add 2 cm in height? See a Pediatric Endocrinologist. ...Read more
My igf-1 level is 75 (n=90-325)-is that good or bad? If I need to increase it, what can I do? I am trying high intensity interval training. What else?
Depends on patient: What sort of meaning a particular igf-1 level has depends on all the other issues that a patient has. A number is just a number. The endocrinologist can take into account the whole situation and help decide the next step. Low igf-1 can be due to gh deficiency, insensitivity to gh, reduced pituitary function, anorexia nervosa or other nutritional deficiencies, chronic liver or kidney disease, etc.. ...Read more
No: Besides, it's injection only and available only by prescription or black market, where who knows what you're getting. Give your body time to fully mature. ...Read more
Yes: Please go to this link and read it http://www. Ncbi. Nlm. Nih. Gov/pubmed/22784832 ...Read more
I'm 17 and 5'8" I want to be 6'0" will taking estrogen blockers and IGF-1 help me grow. My growth plates are still open.
No!: Do not take any drugs to try to help you grow. If your growth plates are open you will continue to grow some, but give up hope for six feet. That is VERY unlikely and no drugs will help in any meaningful way. ...Read more
My husband and me are on a lowcarb diet. Is a lowcarb diet counterproductive for our GH-deficient son due to lower IGF-1 production from lowcarb?
Unlikely to matter: The human body can create any "carb" it needs from any dietary protein or fat. It takes longer and more energy than simply processing dietary carbs, but that is why it works for weight loss. A reduced carb diet has been looked at in teens and found to be safe. Complete elimination of dietary carbs is almost impossible. I don't see any reason your GH kid would suffer. I would discuss it with his doc ...Read more