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See below: Iga is one of the antibodies that is made by our bodies. It is found in the blood but its main function is to be secreted into our tears, mucous membranes and the like. Iga functions as a first line of defense against infections. Pt with IgA deficiency can do quite well and have no symptoms or can have recurrent sinus infections. ...Read more
IgA serum: Iga is an antibody that plays a critical role in mucosal immunity including protection against sinus, ear, and lung infections. It is the main antibody produced daily and secreted in the breast milk, tears, mucous, gastrointestinal tract, lungs and sinuses. Patients with decreased IgA levels can present with recurrent sinus infections, ear infections, and pneumonia. ...Read more
No, IgE = allergies: A high ige is associated with allergies, parasitic infections and some rarer medical conditions. A slightly high IgA is a nonspecific finding and may not be clinically significant. If it's extremely high, like ten times normal, it could mean a plasma cell abnormality, like multiple myeloma. Autoimmune diseases may also cause IgA to become elevated. Ask an immunologist to evaluate you if concerned. ...Read more
My doc sent me for the Celiac panel, Gliadin & Transglutaminase were normal but IGA serum was 424, doc said the norm is 90, what does this mean?
Nonspecific test: IgA is the bodies first line of defense for many infections at the mucosal surfaces. An elevated IgA is often associated with inflammation or infection. The test is very nonspecific alone and I'd advise you to continue to follow up with your physician as per their request for the work up of your symptoms. ...Read more
High albicans, igg, iga, igm. Serum iron and % sat high, T4 low, folate (folic acid) low, b2 low (5.5), B6 high (64)-what do I focus on and what dr.? Bad fatigue
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Depends on values: Elevated IgA level might just represent an adequate response to an infection. If this is the case, when the infection is gone, the levels would come back to normal. Less common, they could be extremely high and might indicative of a proliferative disorder of the cells that produce the iga. ...Read more
Usaully gut!: Inflammation of the GI tract, usually subclinical, is present in all the seronegative arthopathies and IgA is frequently elevated. It is mostly made from lymph tissue ligning the small intestine, called peyer's patches. It is also elevated in regional enteritis and crohn's of the small intestine. In an older person, multiple myeloma must be excluded. ...Read more
How high?: Immunoglobulin A is present in serum (thus measurable by blood test), but its chief importance is in mucous membranes (respiratory tract and gut) and breast milk. Low levels can trigger infections like sinusitis and pneumonia. Mildly elevated levels can be normal, but higher values can be a sign of a form neoplasia (e.g. cancer) of plasma cells. See a hematologist/oncologist. ...Read more
My total serum IgA was 172( in range) in 2012. It has now dropped to 42(lower than normal range). What would cause such a substantial drop?
Unimportant: If that's the only thing in the immunglobulin panel that's abnormal, there is nothing to be concerned over at this time if you are otherwise healthy. ...Read more