Top
10
Doctor insights on: Iga Deficiency

Share
Dr. Zamaneh Mikhak
64 doctors shared insights

Iga Deficiency (Overview)

Selective deficiency of IgA is the most common immune deficiency disorder. Persons with this disorder have low or absent levels of a blood protein called immunoglobulin A.


1

1
Anybody know much about this IgA deficiency?

Anybody know much about this IgA deficiency?

Maybe no issue: Ig a is one of the 5 known immunoglobulins in human. Isolated IgA deficiency occurs in 1/500 of the population and is not usually associated with susceptibility to infections unless there is an igg deficiency as well. If you are healthy otherwise, don't worry about it. On the other hand, was the blood test obtained because she gets frequent sinus or lung infections in the first place? ...Read more

See 1 more doctor answer
Dr. Zamaneh Mikhak
64 doctors shared insights

Iga Deficiency (Overview)

Selective deficiency of IgA is the most common immune deficiency disorder. Persons with this disorder have low or absent levels of a blood protein called immunoglobulin A.


2

2
How often does IgA deficiency progress to cvid? I was tested at 26 and don't have cvid. Is it likely to turn into cvid?

How often does IgA deficiency progress to cvid? I was tested at 26 and don't have cvid. Is it likely to turn into cvid?

Depends on level: If there is true deficiency, 20 % get symptoms before 16 years of age. Most people developed in their 3rd or 4th decade of life.Male and female equally. Recurrent infections of nose, ear, sinus, lung, abdomen, enlarged lymph nodes in neck and abdomen etc. But first of all one should determine if deficiency exit or not by using more sophisticated tests. ...Read more

4

4
I have negative celiac blood test and no IgA deficiency but biopsy shows chronic non-specific duodenitis and celiac symptoms are present.Need help. ?

I have negative celiac blood test and no IgA deficiency but biopsy shows chronic non-specific duodenitis and celiac symptoms are present.Need  help.
?

Be more specific: If IgA tTG was negative, there is a very little chance that you have celiac disease. However, other conditions may mimic gluten-sensitivity and some people may actually be allergic to wheat itself causing similar symptoms. The biopsy findings should be quite specific for gluten intolerance. What actually are your symptoms? ...Read more

See 2 more doctor answers
5

5
What are the tests for IgA deficiency?

What are the tests for IgA deficiency?

Blood test: To determine if you have an IgA deficiency, a simple blood test can be done. ...Read more

6

6
Iga was measured to be low at 40 mg/dl. Range was above 68mg/dl. Dr said it isn't IgA deficiency because it's too high. What caused this then?

Iga was measured to be low at 40 mg/dl. Range was above 68mg/dl. Dr said it isn't IgA deficiency because it's too high. What caused this then?

No IgA deficiency: Your IgA is a little lower than the average. It is not low enough to be called deficiency. Iga deficiency used to be IgA of less than 30mg/dl, occurring in 1 in 500 people. A level of less than 1mg/dl occurs in 1 in 2000 people. The primary cause is unknown, but there is failure of certain b lymphocytes to mature into IgA producing plasma cells. If you have no symptoms - no treatment necessary. ...Read more

7

7
What is IgA deficiency and does it need to be treated?

What is IgA deficiency and does it need to be treated?

Maybe no issue: Ig a is one of the 5 known immunoglobulins in human. Isolated IgA deficiency occurs in 1/500 of the population and is not usually associated with susceptibility to infections unless there is an igg deficiency as well. If you are healthy otherwise, don't worry about it. On the other hand, was the blood test obtained because she gets frequent sinus or lung infections in the first place? ...Read more

See 1 more doctor answer
8

8
What is the treatment for immune deficiency (iga)?

What is the treatment for immune deficiency (iga)?

Good hygiene: There is no medication or treatment for IgA deficiency. You must use good hygiene and hand washing to avoid infection. ...Read more

9

9
Could an IgA deficiency prevent my body from making antibodies?

Could an IgA deficiency prevent my body from making antibodies?

IgA deficiency: Iga is an antibody, so a deficiency of IgA means your body is having trouble making that type of antibody. Iga deficiency does not cause you to be unable to make other antibodies. It just means you aren't able to make the IgA class of antibodies, so antibodies of that type will probably not be detected if they are sought, for example, in a blood test for celiac or other diseases. ...Read more

10

10
My 2 1/2 yr old daughter has a genetic disorder called vcfs (22q11.2 deletion syndrome) with this she has an IgA deficiency which has manifested as recurrent bronchitis. Whats a good website for info?

My 2 1/2 yr old daughter has a genetic disorder called vcfs (22q11.2 deletion syndrome) with this she has an IgA deficiency which has manifested as recurrent bronchitis. Whats a good website for info?

The VCFS Educational: Foundation has webinars. Their conference for parents and professionals is in my home town this year. I couldn't resist adding the iconic photo. If your child has adhd, as is very common in people with vcfs, just know that circus circus can be an overstimulating environment for any child....Or adult. ...Read more

See 2 more doctor answers