Doctor insights on:
Ifex (ifosfamide): See: http://www. Rxlist. Com/ifex-drug. HtmGet a more detailed answer ›
Ifosfamide allergy: Ifosfamide is a chemotherapy medication. An allergy occurs when your body’s immune system creates antibodies to a foreign substance causing a reaction that can be mild to severe. For specific potential adverse effects see: https://www. Drugs. Com/sfx/ifosfamide-side-effects. Html ...Read more
Rarely affects it.: Chemotherapy when given over a prescribed period of time such as in the neoadjuvant setting or post surgery rarely effects fertility. In the presence of metastatic disease where long term therapy is given then there is a chance of infertility. This can be true when doxorubicin and Ifex (ifosfamide) are employed for advanced metastatic sarcoma. ...Read more
Not too good: Some studies have suggested a response to Ifosfamide in small cell Ca of the lung. However there is minimal activity and no evidence of marked survival improvement in non small cell Ca of lung such as adenocarcinoma which is the most prevalent form. Here the Platinum, Taxol drugs have had some improvement as well as in using Tarceva (erlotinib). A better response is being seen with the anti PD-1 drugs. ...Read more
Which is the better cytotoxic drug (adriamycin (doxorubicin) or ifosfamide) for synovial sarcoma?
Chemotherapy for SS: I would potentially seek out an opinion from the mayo clinic oncology department who are not very far north of you. I can help set that up for you. Please contact me at David. Stockman@orthopath. Com ...Read more
Same as before.: There shouldn't be much difference in terms of symptoms from one cycle to the next. It is possible that your bone marrow may rebound more slowly after multiple cycles of treatment, and that can cause lower blood counts, but otherwise the symptoms and side effects should be similar to your prior 2 cycles. ...Read more
The main side effects are alopecia, leukopenia (decline in white blood cells), blood in urine, which is related to a metabolite of the prodrug.Mesna is typically infused along with Ifosfamide to help neutralize the metabolite.
Nausea and neuro toxicities round out the rest of the side-effects. ...Read more
NO SPECIFIC REASON:
Here are 3 possible reasons:
1) Most clinical trials use this sequence, although it has been given after in other studies as well
2) Etoposide is a shorter infusion 1-2 hours, Ifosfamide typically hours to 24 hrs, requiring monitoring of urine
3) Giving etoposide 1st also allows opportunity to give IV hydration prior to ifosfamide ...Read more
Hair loss: Are you going to get more cycles of chemo? If not, your hair will start growing within several weeks in general. Be patient. It will grow. ...Read more
Peripheral t-cell lymphoma cure: chop induction+ifosfamide/mtx + autologous transplant or romidepsim+brenduximab?
Complex problem: Cannot comment with 2 lines of information. Need the entire clinical context. If you seek more detailed information get a formal second opinion. ...Read more
There are none...: Even the strongest opiates only "take the edge off" for people in chronic pain. Meds are only one part of dealing with the pain. A useful tool, but pain is so necessary for survival that we are not "allowed" to monkey with it much. In acute pain, the transition from miserable to less miserable can be great. In chronic pain, it's just part of the plan. ...Read more
Sometimes: Sometimes they are. For the most part, expired drugs simply lose potency once past their expiration date. There are, however, some drugs that actually become harmful if taken after they expire. As such, it is best to throw out any medications you have after a year. ...Read more
ASPRIN: Actually no one has decided on 'safest'. Asprin has been around since before you were born and unless you take too much (yes, too much of anything isn't good) most people are okay with it. If the pain it too severe for asprin you need to know what causes it. Good diagnosis is called for. See the dr. ...Read more