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Doctor insights on: Idiopathic Thrombocytopenia Purpura In Children

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What is idiopathic thrombocytopenia purpura?

What is idiopathic thrombocytopenia purpura?

Autoimmune disease: Idiopathic thrombocytopenic purpura is a bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting. Persons with the disease have too few platelets in the blood. Check this site:
http://www. Ncbi. Nlm. Nih. Gov/pubmedhealth/pmh0001562/. ...Read more

Idiopathic (Definition)

An idiopathic medical condition is one of unknown or obscure cause. In some conditions, there may be known causes as well. For example, themajority of glaucoma cases are idiopathic (unknown cause), but there are some cases related to eye ...Read more


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What is the treatment for idiopathic thrombocytopenia purpura?

What is the treatment for idiopathic thrombocytopenia purpura?

Steroids & surgery: Many cases of itp resolve with supportive care and corticosteroid treatment. In resistant cases, spleen, the site of platelet destruction, may be removed. ...Read more

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Difference between idiopathic thrombocytopenia purpura and thrombotic thrombocytopenia purpura?

Difference between idiopathic thrombocytopenia purpura and thrombotic thrombocytopenia purpura?

The are completely: Different. Itp is the autoimmune destruction of platelets and is managed with immunosuppression - the first line is usually prednisone. Ttp is the microvascular consumption of platelets (small clots). This can be associated with anemia, renal failure, ha and fever. It is a medical emergency and is managed with plasma exchange. ...Read more

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In the case of idiopathic thrombocytopenia purpura is pregnancy dangerous?

High risk pregnancy: It is something that is manageable, however. You should see a perinatologist for your high risk pregnancy to make sure your baby is okay and also see a hematologist through out your pregnancy- to make sure you and baby are okay. Your hematologist will be able to help and give you the necessary treatment as indicated- like-platelet transfusion, ivig, steroid etc. ...Read more

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Painful calf for weeks, how can I tell muscle pain from DVT? 2013ultrasound neg. Have ITP, SLE&vasculitis. DVT possible w/persistent thrombocytopenia?

Painful calf for weeks, how can I tell muscle pain from DVT? 2013ultrasound neg. Have ITP, SLE&vasculitis. DVT possible w/persistent thrombocytopenia?

It is not possible: To tell on clinical exam alone whether a DVT exists. A venous doppler is the only way to know for sure. Yes, you CAN get DVT even with low platelets. Contact your hematology specialist for specific advice. ...Read more

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Itp - idiopathic thrombocytopenic purpura, what is this?

Itp - idiopathic thrombocytopenic purpura, what is this?

ITP is just what...: It sounds like. It is characterized by bleeding, bruising (purpura) and petechiae that develop because of a low PLT count (aka thrombocytopenia), and where the specific trigger for thrombocytopenia is not known (idiopathic). We do know that in itp, the pt makes antibodies to auto-antigens found on the PLT surface (often pla-1) which mark them for destruction. This makes the PLT count low. ...Read more

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How effective is it to be treated with rituximab if itp (thrombocitopenic idiopathic purpura)?

How effective is it to be treated with rituximab if itp (thrombocitopenic idiopathic purpura)?

Faily effective.: Most patients (30-40%) treated with Rituxan (rituximab) weekly x4 will develop normalization of their platelet counts. ...Read more

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Has anyone lost someone to idiopathic thrombocytopenic purpura (itp)? Is it a deadly disease?

Rarely deadly: The risk of dying from a complication of idiopathic thrombocytopenic purpura (itp) is fairly low. Death, if it occurs, is usually related to a bleeding event such as bleeding in the brain. The general estimates are that the risk of death is <1%. ...Read more

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Can you get itp (idiopathic thrombocytopenic purpura) from being around a person who has it? Is it contagious?

Can you get itp (idiopathic thrombocytopenic purpura) from being around a person who has it? Is it contagious?

Not contagious: Itp is an immune-mediated process that leads to a very low platelet count. It is not a contagious condition that you can get from being around somebody with the disorder. ...Read more

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Is thre any treatment for idiopathic thrombocytopenic purpura itp in pregnancy?

Yes.: Itp in pregnancy is treatable. It does depend on what medications have worked in the past. If the itp has never been treated, there are several options. Steroids are often used in pregnancy. The itp, even if treated in the mom, can cause low platelets in the newborn. This may be of more concern if mom has had her spleen removed or if othersib, inge have had trouble with low platelets at birth. ...Read more

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Is it less likely for someone who has idiopathic thrombocytopenic purpura (itp) to experience blood clot such as dvt?

Is it less likely for someone who has idiopathic thrombocytopenic purpura (itp) to experience blood clot such as dvt?

Yes: It can happen because the proteins in your blood that promote clotting are not affected by your deficiency of platelets. ...Read more

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Female, 30 years old, Idiopathic thrombocytopenic purpura (ITP) onset every year for the last 10 years. Each onset: immunoglobulin and oral prednisone, dexamethasone intravenous injection, injection of platelets. Any other solutions?

ITP: Your treatments do sound effective. I would also suggest a treatment to maintain a long-term response. I would see a rheumatologist. Rituxan has been used as well. ...Read more

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Does itp (immune thrombocytopenic purpura) weaken the immune system?

No: Itp does not supress immune system. Itp is treated commonly with immunesupressive agents such as corticosteroids, rituxan- and thse treatment would supresse immune system. ...Read more

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Is itp a form of cancer? Since they found out that I have low platelets in 07. I heaven on IV treatments. My platelets can be 168 an still taktreatment

Is itp a form of cancer? Since they found out that I have low platelets in 07. I heaven on IV treatments. My platelets can be 168 an still taktreatment

No: Ttp is a disorder causing clot formation in microscopic blood vessels and resulting in low platelet counts altered mental status and renal failure. It responds to plasmapheresis. Cause is unknown. Some forms of cancer may be complicated by ttp and there is a genetic form too. ...Read more

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Is it possible that I can get idiopathic thrombocytopenia pupura a second time?

Chronic disorder: Itp in adults is often a chronic disorder. There may be a period of remission which makes it appear that a person is getting the disease second time, when it in fact it was never cured. ...Read more

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How come I have thrombotic thrombocytopenia purpura, but nobody else in the family has it?

Not hereditary: Ttp of thrombotic thrombocytopenic purpura is not a hereditary disease. Most of them is idiopathic i.e. Unknown etiology in about 37 percent. Others are related to drugs, autoimmune disease, infection such as hiv, endothelial injury, stem cell transplant etc. ...Read more

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Can you die from thrombotic thrombocytopenia purpura?

Can you die from thrombotic thrombocytopenia purpura?

YES: Unfortunately, yes.
People can die from ttp. They can develop seizure, coma, renal failure, cardiac hemmorhage/bleeding, sudden cardiac arrest, myocardial infarction etc.
Need to get treatment as soon as possible. ...Read more

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What is the disease? Thrombotic thrombocytopenia purpura?

What is the disease? Thrombotic thrombocytopenia purpura?

Abnormal platelet: Function due to deficiency of a metaloproteinase. Deficiency, usually acquired, of an enzyme that breaks down large multimers of von willebrand factor causes overactivation of platelets leading to intravascular microthrombi that affect the functions of the kidneys, brain, lungs and other organs. It can be treated by transfusing normal donor plasma. ...Read more

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Most common symptoms of thrombotic thrombocytopenia purpura?

Range of symptoms: Ttp can involve many different organs. One can have renal dysfunction, fever, altered mental status, low platelet counts and hemolytic anemia. These signs can lead to symptoms of bleeding, bruising, petechiae, confusion, anemia, fatigue, and possible jaundice among other things. ...Read more

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How common is it for somebody to get thrombotic thrombocytopenia purpura?

Rare disease: This is a rare but life-threatening disease; approx 2-3 cases per 100, 000 population in the USA are seen. ...Read more

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What is the definition or description of: thrombotic thrombocytopenia purpura?

TTP is a serious: Medical condition in which the platelets form clots within the small blood vessels throughout the body. Patients usually come to attention due to low HGB or platelets, but also may have fever, kidney insufficiency, seveer headache, and even seizures and stroke.

This is an absolute medical emergency. ...Read more

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What is the treatment for thrombotic thrombocytopenia purpura?

Plasma transfusion: Ttp is due to deficiency of an enzyme normally present in blood. This enzyme controls the activation of platelets. The deficient enzyme is usually replaced by transfusing plasma and in severe cases by exchanging the patient's plasma with normal plasma. ...Read more

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Is thrombocytopenia purpura as the same as blood dyscrasia?

Is thrombocytopenia purpura as the same as blood dyscrasia?

Different: Thrombocytopenic purpura (ttp) is an acute condition involving destruction of blood components including red cells and platelets and can be life threatening. Blood dyscrasia is a general term referring to a chronic or inherited blood compnent disorder such as hemophilia, leukemia, thalassemia, etc. ...Read more

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Do people with thrombotic thrombocytopenia purpura have a lot of pain?

No usually: People with itp usually bleed more frequently following gently trauma, like a bump. In more severe forms, itp can be associated with gastric hemmorrages, which are painful, but this is rare. ...Read more

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Is being diagnosed with cancer during pregnancy common? 26/f. Itp, ibs-d, hashimotos. 2 children, want #3 but afraid of cancer diagnosis when pregnant

Is being diagnosed with cancer during pregnancy common? 26/f. Itp, ibs-d, hashimotos. 2 children, want #3 but afraid of cancer diagnosis when pregnant

No: It is extremely uncommon to be diagnosed with cancer while pregnant. Do you have itp? This is something to discuss with your doctor prior to getting pregnant but it does not increase your risk of cancer. ...Read more

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Does anyone knows how effective is rituximav if I have itp?

Response rate 20-30%: Recent review in blood in may 2012 looked at several articles and found a 5-year response rate in adults to be around 26%. Meaning these patients had a sustained elevation of their platelet count for 5 years. Initially the response rate is close to 60%. It is given weekly for 4 weeks. So in summary, it works well. Hope this helps. ...Read more

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I had acute itp 16 months ago. Can I donate a kidney?

I had acute itp 16 months ago. Can I donate a kidney?

ITP: Is your ITP controlled and with what agents. Kidney donation is like any other surgery, can be laparoscopic, and laparoscopic with hand assist and finally open. The risk of your bleeding and not the kidney itself. If your transplant ctr is willing to screen and ur plts are stable and functional and bleeding risk is reduced u may donate. Best to call the transplant center and see them and discuss. ...Read more

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Have scaling of the skin on chest history of ITP what should I do?

Have scaling of the skin on chest history of ITP what should I do?

Not related to ITP: If the scaling did not fllow purpuric rash due to ITP it is not related and if it is after purpura that is ok too
You can use Vaseline or Petrolium Jelly
or consult your doctor ...Read more

Non Blanching Red Or Purple Spots (Definition)

Non blanching red or purple spots can describe purpura, which is bleeding beneath the skin that does not blanch with pressure. It can be caused by platelet disorders, coagulation disordes, vascular ...Read more


Purpura (Definition)

Purpura are non blanching red or purple spots caused by bleeding beneath the skin. The spots do not blanch with pressure. They can be caused by platelet disorders, coagulation disordes, vascular ...Read more