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Doctor insights on: I Have A Complex Ovarian Cyst Should I Request Ca 125 Test

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Hi, I'm 48 yo, have endometriosis, ovarian cysts, uterine fibroids, pre-menopausal. CA 125 was around 200's then 159 the last one was 210 any concerns?

Hi, I'm 48 yo, have endometriosis, ovarian cysts, uterine fibroids, pre-menopausal. CA 125 was around 200's then 159 the last one was 210 any concerns?

Likely, no: CA 125 is not recommended as a screening tool for ovarian cancer when used in risk-based stratification. Meaning, assuming that your mom or sister didn't get diagnosed with ovarian cancer. Normal for women with endometriosis to have elevated CA-125. It sounds like your doctor has done Ultrasound to evaluate ovaries as well. Your MD knows your history and risk, likely this CA-125 level is normal ...Read more

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Cyst (Definition)

A cyst is a structure or mass that consists of a cellular lined sac. It is typically filled with fluid but may be filled with solid material. It can be congenital, traumatic, or acquired. They may develop nearly anywhere in the body and usually require complete excision for eradication or they are likely to recur. Fluid filled sacs that are not cellular lined ...Read more


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I have a complex ovarian cyst should I request ca 125 test?

I have a complex ovarian cyst should I request ca 125 test?

Maybe: Talk it over with your doctor. Things to consider are 1) your age and menopausal status, 2) previous history of endometriosis, 3) size of the mass, 4) ultrasound appearance, 5) duration of the problem., 6) family history of ovarian cancer. Remember that ca-125 may be elevated in many benign conditions, as well as ovarian cancer. ...Read more

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Complex ovarian cyst, told need complete hysterectomy & need 2 see oncologic gyn. Is this standard or should I worry? Also sent 4 ca-125 & CEA tests

Complex ovarian cyst, told need complete hysterectomy & need 2 see oncologic gyn. Is this standard or should I worry? Also sent 4 ca-125 & CEA tests

Complex Ovarian Cyst: It is not uncommon for a doctor to be cautious and have you seen by a gyn oncologist with a complex ovarian cyst. Most ovarian cysts are benign but some can be cancerous. The size and ultrasound appearance of the cyst as well as the results of the blood tests may raise or lower the suspicion of cancer. It might be best to ask your doctor what they are thinking because they have those details. ...Read more

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Mildly complex ovarian cyst 4.5cm in postmenausal woman.Ca125 is 15. Having surgery tomorrow so worried! can it be something bad?Help!

Mildly complex ovarian cyst 4.5cm in postmenausal woman.Ca125 is 15. Having surgery tomorrow so worried! can it be something bad?Help!

Talk to doctor: Many women will develop cysts in their life. The vast majority are benign, but some do develop into cancer. Having a ca 125 that low is a good sign, but no one can tell until the cyst is examined by a pathologist after surgery. After surgery, your doctor will be able to give you more detailed answers. ...Read more

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Can an ovarian cyst raise a ca-125 test?

Can an ovarian cyst raise a ca-125 test?

Ovarian cyst: An ovarian cyst can raise the ca 125, but depending on the age, an elevated ca 125 and an ovarian cyst/mass/tumor/growth (all interchangeable names) can be worrisome. ...Read more

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I had a CA-125 done for ovarian cysts (10.5cm and 4cm) Test came back 190. Had another test weeks later and new u/s. Cyst is now 8.4 and CA-125 is 110. Is this even possible? Cysts are hypoechoic cystic lesions possibly endometriomas & endometriosis.

CA-125 testing: CA- 125 testing is notoriously inaccurate when it comes to testing for ovarian cancer especially when endometriosis is a part of the equation. IF there is continued concern most MD's will take a "look/see" with the laparoscope and confirm a definitive diagnosis. ...Read more

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If my roma test is negative why do I still have to see a gynocologist/oncologist for removal of a 7.1 complex ovarian cyst may be serous or municous. I am postmenopausal so the test is 100% right.?

If my roma test is negative why do I still have to see a gynocologist/oncologist for removal of a 7.1 complex ovarian cyst may be serous or municous.  I am postmenopausal so the test is 100% right.?

Ovarian cyst: Correct me if I am wrong. I think you are referring to ova-1 test. The test is designed to evaluate the possibility of benign vs malignant cyst. It is not 100% right. The purpose of the test is trying to designate who should be your surgeon, your gynecologist who usaully treat benign disease or your oncologist. ...Read more

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When your gyn checks you for an ovarian cyst and then asks you to take a blood test for ca-125. Is that a bad sign?

When your gyn checks you for an ovarian cyst and then asks you to take a blood test for ca-125. Is that a bad sign?

CA 125 - Why check?: Cancer antigen 125 (ca-125) is not a screening test for ovarian cancer. It is an adjunctive test for measuring tumor response (ie, a tumor marker) for pts w/ known ovarian cancer. It isn't perfect even when we know someone has ovarian cancer. In the appropriate clinical setting -- eg an abnormal ovary on imaging it might help determine if a mass is benign or malignant, but again is not perfect. ...Read more

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Dr. Sewa Legha
125 doctors shared insights

Ca125 (Definition)

Ca-125 (cancer antigen 125 or carbohydrate antigen 125) is a biomarker/tumor marker for ovarian cancer (etc); however, it is not sensitive or specific enough to use as a screening test. Also, a uk study showed that treating based on ca125 level did not improve outcomes. "125" comes from the 125th attempt to develop a marker. It was introduced by bast ...Read more


Dr. Lonnie Smith
2 doctors shared insights

Ovarian Cyst (Definition)

A growth (often balloon like) on an ovary. It is often thin walled ...Read more