Doctor insights on:
I Have A Brain Tumor Anaplastic Astrocytoma What Do You Do After Surgery
Astrocytoma is a tumor that is arising from a specific cell type in the central nervous system (brain or spine) that is called astrocyte. These are the cells that support the actual nerve cells (neurons). It is a common type of nervous system tumor, which has different types, benign to malignant. Treatment is tailored according to this as well ...Read more
Chemoradiation: I would recommend proceeding with a combination of chemotherapy and radiation. These tumors have a high likelihood of recurring. Chemoradiation gives the best chance to minimize that risk. Despite stories of how bad chemotherapy and radiation can be, these are 'life saving medicines' and 'healing beams.' I would recommend giving yourself the best chances you can. ...Read more
What are the chances of a brain tumor anaplastic astrocytoma gr 3 reaccuring in a child if the tumor was removed?
High: Unfortunately pediatric anaplastic astrocytoma (grade 3 glioma) has high recurrence rates. Degree of resection does impact prognosis. However, those with grade 3 astrocytoma tend to have pfs(progression free survival) of 40 to 50% even with adjuvant chemotherapy and radiation. ...Read moreSee 1 more doctor answer
Astrocytoma: Anaplastic astrocytoma is a rare malignant brain tumor. Astrocytomas are tumors that develop from certain star-shaped brain cells called astrocytes. Grades i or ii astrocytomas are nonmalignant and may be referred to as low-grade. Grades iii and IV astrocytomas are malignant and may be referred to as high-grade astrocytomas. ...Read more
Was a healthy 39 year old brain tumor patient who had a grade 3 astrocytoma brain tumor removed with 7 hours of brain surgery?
Question is vague: It seems that you are asking if it is possible for a 39 yo to have a grade iii astrocytoma and undergo 7 hours of brain surgery. This is not an unusual scenario. Often times these tumors are infiltrative and take a lot of time to dissect and remove.The prognosis is dependent on molecular markers, response to chemo and radiation. Work closely with your neurosurgeon, oncologist, radiation oncologist. ...Read more
What is an over expression of p53 brain tumor pathology? Is this good or bad? Grade2 astrocytoma 31 y/o male
Not clearly bad: Many low grade astrocytomas (grade ii) have p53 gene mutations which lead to overexpression of the protein (more precisely the protein is more stable than normal and isn't degraded. There is no completely clear evidence of a higher risk of progression to high grade, or of other bad outcomes, from the p53 gene status or protein levels. ...Read moreSee 1 more doctor answer
Please let me know if there is any effective way to treat brain tumor-junior pilocytic astrocytoma?
Yes: Most pilocytic astrocytomas occur in the cerebellum and the best treatment is neurosurgical removal, which is usually curative. Other locations also deserve surgery but total removal may be less feasible, for example in the optic chiasm and hypothalamus. In such cases some relatively well-tolerated chemotherapy may be helpful. Get several opinions from neuro-oncologists and neurosurgeons. ...Read more
The differential is: Between primary glial tumors and extra-cns metastasis. There are also meningioma, pituitary and pineal tunors that are extra-glial. But none are regular. Glial tumors are graded from low to hi grade with survival decreasing as grade rise from i-iv. ...Read moreSee 1 more doctor answer
If i quit my job to due the fact that I have been diagnosed with an astrocytoma brain tumor. Do i qualify for any benefits?
Depends: A lot would depend on the effects that you are suffering from the brain tumor and/or the treatments. If there are disabilities such as headaches, seizures, problems with thinking, problems with motor function there are disability benefits. Also, if this is a malignant form or if it is considered cancer, there certainly are health benefits such as qualifying for medicare or medicaid. ...Read more
I've gotten epilepsy all ur life, then developed a stage 3 astrocytoma brain tumor recently, how will the epilepsy affect the brain tumor and visa vera?
Complex: The epilepsy won't affect the tumor, indeed it may be a result of the tumor. Removing the tumor surgically and following with radiation and/or chemotherapy will help with seizure control. Some anti-seizure medications interfere with some chemotherapy, so your doctors will have to adjust what they give you to avoid problems with that. ...Read more
Operated for Astrocytoma Grade 3 left frontal brain tumor.Will go for radio nd chemo therapy in a few days.Which precautions/alternative can be taken?
Define your terms: Not clear what you mean by "precautions" or "alternatives." Precautions re XRT and chemo or for something else? The "alternative" to treatment is to do nothing; or to resort to traditional Indian medicine, which is the same as doing nothing, & don't let any well-meaning but ignorant laypeople or charlatans tell you different; unless all you're interested in is feeling better about dying. ...Read more
Depends: Some gliomas in the stem are focal and low grade, and may be located in places where they can be operated upon successfully and safely. However "brainstem glioma" is most often used to describe diffuse infiltrating pontine gliomas, which are high grade and almost always fatal. These are most commonly seen in children. ...Read more
Get best care: The optimal care for a high grade glioma will often be found at a major academic medical center. Treatment is first surgery, to remove the maximum amount of tumor possible, followed by radiation and chemotherapy, often together. All of this also requires good neuroradiology, good neuropathology, good nursing care and supportive care of all types. Don't be shy about asking for second opinions. ...Read more
Depends: Some gliomas are low grade, grow slowly, and are highly treatable, so patients live many years with them. Others are high grade, rapidly growing, and respond poorly to treatment, and do survival is shorter. Age, extent of resection, and some other genetic, epigenetic, and pathological variables also affect survival. Ask your doctor for referral to an expert. ...Read moreSee 2 more doctor answers
Can anyone tell me does radiation or chemo actually offer a decent quality of life for the limited life expectancy of a stage 4 glioma brain tumor?
Yes: For many patients (not all) surgery, then radiation with chemotherapy, and "maintenance" chemotherapy can give a good quality of life for a period of time for patients with grade IV astrocytomas. Half of all patients with current best therapy for these tumors live over a year, and most of that time should be reasonably good quality unless the tumor has caused irreversible neurological deficits. ...Read more
Location: It depends on the location of the tumor. If the tumor is close to memory centers then amnesia might happen, otherwise, if tumor is located in the motor center or sensory center of the brain then brain surgery might affect motion, sensation, speech etc based on the area affected. Always consult with neurosurgeon. ...Read more
Ask your doctor: Your surgeon who operated on your tumor must be the best person to guide you. So ask him. But in general most operations on the brain take 3-4 weeks to heal unless you have paralysis which can take much longer. I would ask you to go slow and temper your enthusiasm for ride roller coasters too soon. ...Read more
Not uncommon: Unfortunately, even with full tumor resection, only 80% of patients will have complete seizure disorder relief. 10% or so will note improved seizure frequency/intensity and the rest of the patients will have no improvement of their seizures despite surgery. ...Read moreSee 1 more doctor answer
This largely relates to cancer cells and is a description of how variant the structure and division pattern is from normal cells. An anaplastic cells has weird internal componens, sometimes extra nuclei, and a bizarre pattern of division. They are usually more rapidly dividing and are a serious type of abnormality ...Read more
"tumor" literally translates as "mass", so even a fresh bruise could be called a "tumor". Doctors use the term "neoplasm" (tranlates literally as new growth) to describe tumors that are abnormal growths of cells. These may be benign or malignant; "malignant" = cancer. In everyday usage, we use "tumor" ...Read more
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