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Doctor insights on: Hypothyroidism Low Rbc High Mcv Mch

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Suffering from incredible fatigue, muscle soreness, water retention lab results show normal wbc, low rbc, high mcv/mch, low lymph absolute. Dr ignore?

Suffering from incredible fatigue, muscle soreness, water retention  lab results show normal wbc, low rbc, high mcv/mch, low lymph absolute. Dr ignore?

Low RBC and fatigue: You need to go back to your physician, or whomever ordered the blood test. You have a low rbc, and i assume, by that, you are anemic. With a high mcv, you may have a b-12 or folate (folic acid) deficient anemia. See your physician asap to discuss your anemia's its cause and treatment. Also, get a referral to a cardiologist to evaluate your cardiac function once your anemia is no longer a problem. ...Read more

Dr. Su Fairchild
1,257 doctors shared insights

Hypothyroidism (Definition)

When the thyroid gland is overactive and too much thyroid hormone is produced, which speeds up metabolism. This results in weight loss, a quick heartbeat, sweating, nervousness, ...Read more


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Low RBC 4.440 x10(6)/mcL + WBC 4.20 x10(3)/mcL , high MCV 95.4 fL + MCH 32.2 pg , what does this mean and what could be the cause?

Low RBC 4.440 x10(6)/mcL + WBC 4.20 x10(3)/mcL , high MCV 95.4 fL  + MCH 32.2 pg , what does this mean and what could be the cause?

Further workup: This isn't a high MCV in my book, and the lowish red count can mean lots of things. If your hemoglobin / hematocrit are low, your physician should undertake an investigation of your anemia, beginning with a good history and physical exam, and confirmatory labs very likely including a reticulocyte count. ...Read more

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Lupus/150mg azathioprine..low rbc..WBC 3.4 .. mcv high(101)...high mch(34)..high rdw (16) concern or is side effect of medicine? My vit b is normal.

Lupus/150mg azathioprine..low rbc..WBC 3.4 .. mcv high(101)...high mch(34)..high rdw (16) concern or is side effect of medicine? My vit b is normal.

Suspect medication: I would first suspect medication. As you know we can find some of the same findings in people with lupus. It depends what your physician has noted before youyou started azathioprine your serial blood studies have shown ...Read more

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What does it mean to have low RBC, low hematocrit, low MPV, low Lymphocytes, low urea, low albumin, high MCV, and high MCH?

What does it mean to have low RBC, low hematocrit, low MPV, low Lymphocytes, low urea, low albumin, high MCV, and high MCH?

Macrocytic anemia: Please forgive my frankness and the appearance perhaps of flippancy. In our dysfunctional health care system, physicians often have less time to explain and educate. This is serious and you must insist on an explanation. ...Read more

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High MCV & MCH for few years. 2 yrs of low rbc. New CBC has folate (folic acid) & calc. Defic., low bun. 2 mnths ago found soft clavicle lymph "mass". Esophag spsm?

High MCV & MCH for few years. 2 yrs of low rbc. New CBC has folate (folic acid) & calc. Defic., low bun. 2 mnths ago found soft clavicle lymph "mass". Esophag spsm?

Lots of info: Here. Possible relevance undetermined. From a heme standpoint high MCV and folate (folic acid) deficiency would go together. Folate (folic acid) supplements would be indicated. Cannot relate to esophageal issues. ...Read more

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Have hypogammaglobulinanemia. Furth test-pretty low IgG and iga, but IgM not detected, lt chains norm. Cbc-my creatinine high, calc. Low, rbc's low, RDW low, MCV high, MCH high, mpv low. Back/hip pain?

Have hypogammaglobulinanemia. Furth test-pretty low IgG and iga, but IgM not detected, lt chains norm. Cbc-my creatinine high, calc. Low, rbc's low, RDW low, MCV high, MCH high, mpv low. Back/hip pain?

Too complex here: Your question is too complex to answer in a few sentences with little information you provide. When there is hypogammaglobulinemia, you should see a well trained immunologist. It could be primary immunodeficiency or it could be secondary due to protein loss in urine since you mention you have kidney disease. Protein losing nephropathy can cause igg loss too. ...Read more

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5 year old has persistent normocytic anemia. High WBC, platelets, low RBC and hemoglobin. Normal MCV, MCH, ferritin and reticulocyte. What's the cause?

5 year old has persistent normocytic anemia. High WBC, platelets, low RBC and hemoglobin. Normal MCV, MCH, ferritin and reticulocyte. What's the cause?

Need more tests,,,: This is hard to determine as this is the case of a child. Other tests like a peripheral blood smear might help to find the cause. It would be best to see the doctor, preferably a pediatrician, for more tests and an exam. Best of luck. ...Read more

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High MCV and MCH for a few years. 2 yrs of low rbc. Recent CBC now has folate (folic acid) & calc. Defic., low bun. 2 mnths ago found soft clavicle lymph "mass". Esophageal probls. & hypogammaglobulinemia. Help?

High MCV and MCH for a few years. 2 yrs of low rbc. Recent CBC now has folate (folic acid) & calc. Defic., low bun. 2 mnths ago found soft clavicle lymph "mass". Esophageal probls. & hypogammaglobulinemia. Help?

Needs more info: Difficult to say based on limited info. High MCV likely due to low folate (folic acid) (did you check b12?). Low BUN is good, so no worries. If you have a clavicular lymph node it needs evaluation for sure. See your doctor! ...Read more

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Male 26, low RBC 4.39*10^12, total haemoglobin 13.2g/dl, MCV 88fl, MCH 30pg, mchc 34 g/dl, reti index 0.84%, ESR 2ml/hr cause of low rbc?

Male 26, low RBC 4.39*10^12, total haemoglobin 13.2g/dl, MCV 88fl, MCH 30pg, mchc 34 g/dl, reti index 0.84%, ESR 2ml/hr cause of low rbc?

Borderline anemia: Your hemoglobin is also a wee bit low for a man (most men have 13.5 or more). The explanation might be something as simple as having drunk a few extra glasses of water before the blood draw so that you could also provide a urine sample. Your physician may want to check you now for occult blood loss, repeat the cbc, or begin an anemia workup now despite normal indices. Good luck. ...Read more

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28wks pregnant with hypothyroidism.Low = haemoglobin, platelets, RBC, haematocrit &lymphocytes. High MCH, MCV quite high. Anaemia? or possible cause?

28wks pregnant with hypothyroidism.Low = haemoglobin, platelets, RBC, haematocrit &lymphocytes. High MCH, MCV quite high. Anaemia? or possible cause?

Anemia and pregnancy: Being pregnant can cause anemia. Discuss with your obstetrician. It also depends what your haemoglobin was before you were pregnant. ...Read more

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Have low wbc 2.2 and low rbc. high mcv and rdw. UA RBC 1+ and WBC 3+ and protein H, I don not have a bladder infection. Does this indicate anything?

Have low wbc 2.2 and low rbc. high mcv and rdw.  UA RBC 1+ and WBC 3+ and protein H, I don not have a bladder infection.  Does this indicate anything?

Maybe serious see MD: That's a very low WBC count. Combined with anemia ("low RBC"), a serious nutritional or bone marrow problem is likely, including leukemia and other cancers. The abnormal urinalysis may be an entirely separate problem but also could be serious. You need to see a doctor -- or if already in care, ask her these questions and also whether you should see a specialist. Good luck! ...Read more

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My husband has a high lymphocyte %, low RBC count, and high mch, what does all this combined mean?

My husband has a high lymphocyte %, low RBC count, and high mch, what does all this combined mean?

Insufficient info: Your husband may be anemic and needs further evaluation for the cause. A high mean corpuscular hemoglobin concentration has little meaning absent a full picture of all other parameters measurable. The high % of lymphocytes, again, in and by itself, has little impact on establishment of a diagnosis. Labs are of little value absent good history, physical exam and a thoughtful knowledgeable doctor. ...Read more

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Hi. I am a bit freaked out. I have a high MCH, low MPV and low RBC. I am tired all the time. What is wrong with me?

Hi.  I am a bit freaked out.  I have a high MCH, low MPV and low RBC.  I am tired all the time.  What is wrong with me?

Need more info: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, it would have helped to have the actual results not high and low. What is your hemoglobin?
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex. ...Read more

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Low rbc, low hgb, high mcv, normal iron & B12 levels. What is the cause of anemia?

Low rbc, low hgb, high mcv, normal iron & B12 levels.  What is the cause of anemia?

Macrocytic anemia: The most common causes of macrocytic anemia are B12 (ruled out for you) and folate (folic acid) deficiencies. Folate (folic acid) deficiency can be caused by diet (very rare - folate (folic acid) is everywhere), celiac disease, alcoholism, or hemolysis (autoimmune process, for example). Rarer causes include aplastic anemia and myelodysplastic syndrome (mds). If not clear to your doc, may need to see hematologist. ...Read more

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My CBC results are WBC of 3.5 (low), rbc: normal, hemoglobin 12.3, MCH of 25.2 (low), mchc of 31.5, RDW of 18.4 (high), neutrophils 21, lymphs 74, ?

Need a work-up.: You might have one or more issues here. You have a low WBC count with about 75% lymphocytes, which can mean a leukemia or lymphoma. In addition you've a high RDW and low mch, with a normal rbc count which can mean that cells are being pushed out of your bone marrow by whatever is affecting your wbcs. You should see your doctor for more tests, a look at your blood smear, and a full work-up. ...Read more

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Hi, I have recurrent low RBC's (but Hgb & HCT usually normal), & low WBC's on CBC. Also, low NE# & LY#, High MCH. Does this look like leukemia or HIV?

Hi, I have recurrent low RBC's (but Hgb & HCT usually normal), & low WBC's on CBC. Also, low NE# & LY#, High MCH. Does this look like leukemia or HIV?

See hematologist: Can't tell what may be y9ur problem without more history. Suggest you consult a hematologist There is certainly no evidence that your problem is from leukemia. ...Read more

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Labs: *MILDLY* LOW: RBC, Hgb, Hematocrit. Ferritin/Iron studies are normal. Serum Folate is LOW. Would MCV + RDW have to be HIGH for Folate-Anemia?

Labs: *MILDLY* LOW: RBC, Hgb, Hematocrit.
Ferritin/Iron studies are normal.  Serum Folate is LOW.
Would MCV + RDW have to be HIGH for Folate-Anemia?

Try HealthTap PRIME: Lab results usually are numbers, and numbers are just numbers, with little meaning unless a doctor takes in the whole picture of what's going on with his patient. Getting all the details around a set of numbers is helpful in making interpretations. Try our premium forum, HealthTap PRIME, for a virtual consultation, in which a doctor can ask questions and look over the lab results to explain them. ...Read more

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Low wbc,low rbc,low igm,low neutrophil,low monocyte,hematocrit and hemoglobin levels are within range,mcv high,an ocassional myocelyte. Pt/ptt unknow?

See hematologist: You need to consult a hematologist. Some of the findings may be related to vitamin B12 or folic acid deficiency but the whole picture is unclear especially given that the hematocrit and hgb levels were normal. ...Read more

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Low RBC (4.3), high MCV (95), low platlets (190) high mpv (13.5). B12/iron ok+ ferritin high 270 ng/ml. Tsh - 2.5, suffering from fatigue spells..

Low RBC (4.3), high MCV (95), low platlets (190) high mpv (13.5). B12/iron ok+ ferritin high 270 ng/ml. Tsh - 2.5, suffering from fatigue spells..

What is the: Hemoglobin (hgb)? None of the values you are reporting are significantly abnormal. Need the whole clinical and lab picture to sort this out. ...Read more

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Pediatric cancer? low RBC, low WBC, low platelets, low IGM, high MCV, low neutrophils, low monocytes and low eosinophils, occasional myelocytes,

Pediatric cancer? low RBC, low WBC, low platelets, low IGM, high MCV, low neutrophils, low monocytes and low eosinophils, occasional myelocytes,

Tough set of labs: Suppression of multiple cell lines certainly is a concerning finding on a CBC. Yes, there are pediatric cancers that may present with this type of blood test results. Talking to your heme/onc specialist as soon as possible would be advisable! But don't jump to conclusions because a specialist with the "whole picture" may give you a very surprising answer! ...Read more

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I had a CBC that was normal. 7 days later, start Bactrim for Lyme. 5 days thereafter, CBC shows mild anemia (low: RBC, Hgb, Hematocrit), with normal iron/ferritin. Low Folate, normal MCV. IS THIS FOLATE DEFIC. ANEMIA OR BACTRIM: APLASTIC ANEMIA?

I had a CBC that was normal.  7 days later, start Bactrim for Lyme.  5 days thereafter, CBC shows mild anemia (low: RBC, Hgb, Hematocrit), with normal iron/ferritin.  Low Folate, normal MCV.  IS THIS FOLATE DEFIC. ANEMIA OR BACTRIM: APLASTIC ANEMIA?

Could be a problem: Red blood cells live about 3 months, which means there should not be a big drop in a previously normal person's blood count after just 12 days. That means 90% of a person's red blood cells present today, should still be present 12 days from now. A big drop in RBC's, Hgb, and Hct would mean a need to recheck the blood test and/or look for some cause of loss of existing red blood cells. ...Read more

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What does having low HB, HCT, MCV, MCH, MCHC & high RDW but normal RBC & ferritin mean? HB 10(11.2-14.1) RBC 4.15(3.85-5.02) Ferritin 5.7(4.6-204)

What does having low HB, HCT, MCV, MCH, MCHC & high RDW but normal RBC & ferritin mean?
HB 10(11.2-14.1) 
RBC 4.15(3.85-5.02) 
Ferritin 5.7(4.6-204)

Need iron: It means you have an iron deficiency leading to anemia. It could be not enough iron in your diet to replace menstrual losses but you should check with your doctor to be sure and to receive a recommendation for treatment. ...Read more

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Mcv 69, MCH 22.6, mchc 32.7 (low), high RDW 16.1. Hg/hct normal. Rbc 6.45 (high). Numbers have declined over past 7 months. Iron norm. What is cause?

Need evaluation: All lab results need to be evaluated in the clinical context and the doctor who ordered the test is usually in the best position to do that. It would also help to have the actual results of iron studies. Iron deficiency is a common cause of microcytic hypochromia. Mild thalassemia being another one. If your results are improving, recovery from iron deficiency is a likely explanation. ...Read more

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Should I be concerned about low MCV, MCH, MCHC, A/G RATIO and high Alkaline Phosphatase, RBC, and Glucose. Lvls in order are 67.0, 21.2, 31.7, 1.0,157?

Should I be concerned about low MCV, MCH, MCHC, A/G RATIO and high Alkaline Phosphatase, RBC, and Glucose. Lvls in order are 67.0, 21.2, 31.7, 1.0,157?

Need numbers & info: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, the numbers for the results are missing in your message. Why were these tests done? Do you have any symptoms? ...Read more

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My blood test shows: fraction immature reticylocytes high .19, RBC low 3.82, MCV high 382, MCH high 34.3, lymphocyte low 24%. What could be wrong?

My blood test shows: fraction immature reticylocytes high .19, RBC low 3.82, MCV high 382, MCH high 34.3, lymphocyte low 24%. What could be wrong?

B12/folate deficient: You need to be checked out for vitamin B12 or Folic Acid deficiency. I wonder why the doctor who ordered the blood test did not recommend getting these tests done. If these values were normal, then further studies will be required. ...Read more

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My RBC and hgb is low, while my MCV and MCH is high. Also my lymphocyte is 47, atypical lymphocyte is 5, and eosinophil is 5. What causes this?

My RBC and hgb is low, while my MCV and MCH is high.   Also my lymphocyte is 47, atypical lymphocyte is 5, and eosinophil is 5.   What causes this?

Need more info: Lab results need to be interpreted in the clinical context and the doctor who ordered the test is usually in the best position to do that. See this site for information about anemia and discuss the matter with your doctor.
http://www.mayoclinic.com/health/anemia/ds00321. ...Read more

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What does it mean to have normal Hb 13 with low mcv 76 (80-94) and low mch 23(27-32)?? my rbc count is high 5.5 (4-5.2 ) could it be thalassemia ?

What does it mean to have normal Hb 13 with low mcv 76 (80-94) and low mch 23(27-32)?? my rbc count is high 5.5 (4-5.2 ) could it be thalassemia ?

It could be: Thalassemia diagnostic tests may include a routine blood count, hemoglobin electrophoresis to find out the types of hemoglobin one has in one's blood, and sometimes DNA analysis to try to see if certain mutations are present. "Thal. minor" is somewhat common in certain parts of the world, and in certain populations. A doctor can evaluate to see if anything else might be causing the lab results. ...Read more