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Doctor insights on: Hypothyroidism And Iron Overload

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What is iron overload, hemochromatosis?

What is iron overload, hemochromatosis?

Too much bodily iron: As a result of the inability to increase iron loss, iron overload is an inevitable response to increased iron entry into the body. This can occur by one of three mechanisms - nutritional intake, increased absorption, parenteral sources (i.e. Transfusions). Hemochromatosis is abnormally high absorption of iron as result of a genetic defect. Extra iron can be toxic. ...Read more

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Dr. Su Fairchild
1,212 doctors shared insights

Hypothyroidism (Definition)

The thyroid gland is an endocrine organ located in the front part of the neck. Its role is to make thyroid hormones, which control the way cells use energy. Hyperthyroidism results when the thyroid gland is overactive and too much thyroid hormone is produced, which speeds up metabolism. This results in weight loss, a quick heartbeat, sweating, nervousness, ...Read more


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What iron levels are considered "suspicious" for iron overload/hemochromatosis?

What iron levels are considered "suspicious" for iron overload/hemochromatosis?

Transferrin sat: Your best screen is transferrin saturation. Many of us think that the current recommendation of 45% or more for women, 50% of more for men miss too many people. If you actually have evidence of liver troubles (elevated SGOT / SGPT, for example), think about getting a serum ferritin. With a family history, get the gene testing to know early. ...Read more

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Is there a treatment for iron overload?

Yes: Phlebotomy which is removal of red blood cells or oral drugs that block iron absorption alos IV drug that binds iron see a md. ...Read more

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Is iron overload/hereditary hemochromatosis "curable"?

Is iron overload/hereditary hemochromatosis "curable"?

Yes: Yes as long as the iron is removed before irreversible damage like cirrhosis or diabetes has occurred. Phlebotomy is the best way to remove the iron. ...Read more

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Can iron overload be acquired?

Can iron overload be acquired?

Yes: Certain beers in the tropics caused iron load. So even in patients that did not have hemochromatosis did not develop iron overload. Also, patients with history of multiple blood transfusions can also develop iron overload. There was a famous bantu beer. Most patients cannnot get iron overload unless they have the genes. ...Read more

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What should I expect from iron overload?

What should I expect from iron overload?

Lots : Liver problems, heart disease, muscle disorders, brain problems, kidney disease. If you have iron overload, please get it treated as soon as you can. Not a nice thing to have. ...Read more

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What are some of the symptoms of iron overload?

What are some of the symptoms of iron overload?

Hemachromatosis: Iron overload or hemachromatosis hs following symptoms abdominal pain, fatigue, generalised darkening of skin colour, joint pains, lack of energy, loss of body hair, loss of sex desire, weakness. ...Read more

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How serious is iron overload, hemochromatosis?

Can be deadly: Over time, excesses of iron build up in major organs such as the heart, liver, pancreas, joints and pituitary. If the extra iron is not removed, these organs can become diseased, causing conditions like diabetes mellitus, irregular heart beat or heart attack, arthritis, cirrhosis of the liver or liver cancer, gall bladder disease, depression, impotence, infertility, hypothyroidism, hypogonadism. ...Read more

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Could I have iron overload if hemoglobin is normal?

Absolutely: Contrary to what anybody else might have told you, your hemoglobin level is not your "iron" level. The two numbers are quite different. In fact, in hemochromatosis (a life-threatening but easily treated and very common illness), the hemoglobin is usually normal while total body iron may exceed the upper limit of what's good by 20x or more. ...Read more

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What are the symptoms of iron overload, hemochromatosis?

What are the symptoms of iron overload, hemochromatosis?

A few: Lack of energy, abdominal pain, memory fog, loss of sex drive, heart flutters, irregular heart beat. When symptoms are associated with hemochromatosis, these usually begin in men in their late 20’s to early 30’s. In women, symptoms usually start about 10-15 years after they stop having a period due to menopause, birth control pills or hysterectomy. ...Read more

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Iron (Definition)

In the metal group ...Read more