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Doctor insights on: Hypothalamus Adrenals Cortisol Response Myasthenia

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Could my hypothalamus be giving orders to the adrenals to produce a surge of cortisol in response to my myasthenia gravis?

Could my hypothalamus be giving orders to the adrenals to produce a surge of cortisol in response to my myasthenia gravis?

Yes: The hypothalamus will stimulate the adrenals when there is any physical, mental or emotional stress. If the myasthenia is symptomatic, that is a stress and could stimulate the hypothalamus. ...Read more

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Hypothalamus (Definition)

An area of brain that deals with maintenance of homeostasis throughout the body. Important for temperature, appetite, weight regulation, coordination with other areas ...Read more


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I have vomiting episodes that lead to systemic inflammatory response syndrome without sepsis. What causes sirs? Insufficient cortisol from adrenals?

I have vomiting episodes that lead to systemic inflammatory response syndrome without sepsis.  What causes sirs?  Insufficient cortisol from adrenals?

Multifactorial: As a general rule, inflammatory conditions which produce the criteria necessary to term a condition sirs are induced by cytokine release, but there are many other possibilities. Generally not adrenal insufficiency. You seem to be trying to acquire a shorthand medical education. It is not that simple. ...Read more

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I found out that I have low fasting cortisol 111 nmol/l , does that mean all my adrenal hormones are low?

I found out that I have low fasting cortisol 111 nmol/l , does that mean all my adrenal hormones are low?

WHile your: Result is low, one abnormal test doesn't make a diagnosis. It needs to be repeated with an 8am blood cortisol at a quality lab and correlated with historical and physical exam data (plus potentially other lab tests) by your physician. Besides, the other adrenal hormones are controlled by different mechanisms than cortisol. ...Read more

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How is cortisol related to an adrenal imbalance?

How is cortisol related to an adrenal imbalance?

Too Much/Too Little: While the adrenal gland makes several hormones, too little or too much cortisol is usually the problem for adrenals that are under- or overactive. Adrenal insufficiency, or failure, causes weight loss, muscle weakness, low blood pressure, and can be fatal. In cushing's syndrome (too much cortisol) weight gain, the face may be round, and there is increased risk for diabetes and high bp. ...Read more

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Hi, (Adrenal question) Can you have a normal ACTH test and still have low cortisol or adrenal.issues?

Hi,

(Adrenal question)

Can you have a normal ACTH test and still have low cortisol or adrenal.issues?

Yes: A spot ACTH test is not especially helpful in the workup of possible adrenal disease. It's all about stimulation and suppression testing. ...Read more

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Cortisol, a.M. Test 15.7. No p.M. Test. Concerned re adrenal glands: 20+ cort. Inj. In 2011. Should I have the a.M. And p.M. Tests?

No: Your values are normal (both am cortisol and acth stimulation test). No concern about adrenal insufficiency at this time. The pm test is good to rule out cushing's syndrome, which is not a problem for you either. ...Read more

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Can high pm cortisol point to a problem with adrenal glands?

Can high pm cortisol point to a problem with adrenal glands?

Not at all: since the hormone is being put out. Could in theory could be a growth from the adrenal gland putting out extra hormones. We'd have to see the values the lab normally gets to know if this is even abnormal. ...Read more

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How do multiple steroid shots effect cortisol level and adrenal functioning?

Cortisol shots: Cortisol shots will increase your blood cortisol level and look after your adrenal glands. Please go online and look for "cortisol shots" - you will learn a lot. Take your time reading the several articles. ...Read more

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Adrenal stim test. Baseline cortisol at 0930 is 17.3, at 1000 is 18.9, at 1030 is 20. Ref range is 3.7-19.4. What causes wnl baseline/min elevation?

Normal: These cortisol levels are totally normal. Often the morning cortisol can be mildly elevated from expected norms as a result of stress. However, this stim test is normal. ...Read more

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Would acth and cortisol be low or high with adrenal insufficiency?

Would acth and cortisol be low or high with adrenal insufficiency?

Cortisol: Would be low. Acth would be high if it were an adrenal cause; low if it was a pituitary cause. ...Read more

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If high cortisol can decrease serotonin levels then can low cortisol(like due to iatrogenic adrenal suppression) increase serotonin levels?

If high cortisol can decrease serotonin levels then can low cortisol(like due to iatrogenic adrenal suppression) increase serotonin levels?

That: Is a tricky one because there is not enough evidence of low cortisol causing low levels of serotonin. Depression, chronic and severe, is associated with low serotonin and could lower cortisol levels. ...Read more

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In daily adrenal insufficiency supplementation, which is worse: one peak of cortisol in the upper 30s or low 40s, or three peaks between 16 and 22?

In daily adrenal insufficiency supplementation, which is worse: one peak of cortisol in the upper 30s or low 40s, or three peaks between 16 and 22?

Not studied: Hi. I hope very much you were correctly diagnosed. Assuming so, I do not know why your doc is even checking peak cortisol levels...well known and shown to not be valuable or predictive of problems. Use the lowest hydrocortisone (= cortisol) or prednisone dose needed to prevent hypo adrenal symptoms. Blood cortisol levels are not helpful. Good luck! ...Read more

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Am cortisol too high- taking metformin for hypoglycemic symptoms-would like to address adrenal problem also-can i take seriphos at the same time ?

Am cortisol too high- taking metformin for hypoglycemic symptoms-would like to address adrenal problem also-can i take seriphos at the same time  ?

You sound confused: Metformin is a medication used to treat hyperglycemia (high sugars) not hypoglycemia (low sugars). A single morning cortisol level is a fairly worthless test. What makes you think you have an adrenal problem? Seriphos is a supplement that has no medical studies that show that it does anything helpful for you. ...Read more

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Will srni s help after an adrenal insufficiency is treated? Struggling with symptoms and bloodwork (cortisol) is on the low side of normal in the morn

Will srni s help after an adrenal insufficiency is treated? Struggling with symptoms and bloodwork (cortisol) is on the low side of normal in the morn

Proven?: Adrenal insufficiency diagnosis requires more than a morning cortisol. Is this addison's or is it more central, from the hypothalamus/pituitary? Other associated hormone deficiencies? Moods may be directly affected by hormone imbalances. A complete work up is essential. If adrenal insufficiency is being considered as a diagnosis an endocrinologist has to be involved. Feel better! ...Read more

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What are the best supplement instead of cortisol for adrenal fatigue?

What are the best supplement instead of cortisol for adrenal fatigue?

May not need it: Adrenal fatigue is often a fake diagnosis. The adrenal makes cortisol and adrenaline, which are stress hormones. People who are stressed out and having trouble coping are sometimes persuaded that it’s the adrenal’s fault. This is usually not true. Poor adrenal function is determined by an acth (cotrosyn) stim test, and not by measuring just one blood or saliva level. See an endocrinologist. ...Read more

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Lo cortisol, all symptoms, no tumor, what can be cause for adrenal insufficiency that's not addisons?

Lo cortisol, all symptoms, no tumor, what can be cause for adrenal insufficiency that's not addisons?

Hard to test for: Hi. First of all, there's NO symptom associated with adrenal insufficiency that is SPECIFIC for adrenal insufficiency. If your endocrinologist suspects adrenal insufficiency, several tests can be used depending on clinical suspicion: insulin tolerance test and metyrapone test test the whole hypothalamic/pituitary/adrenal axis; ACTH 1-24 (Cosyntropin) can test only adrenal glands failure; useful 2 ...Read more