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Hypothalamus Adrenals Cortisol Response Myasthenia
Yes: Should there be loss of adrenocortical function, steroid replacement is advocated to rebuild the normal stamina. ...Read more
Test adrenal fxn.: This test is to check on whether or not your adrenal glands are working right. The acth action is to increase production and release of corticosteroids. In the test, a small amount of synthetic acth is injected and the amount of cortisol the adrenals produce in response is measured. This is used to check for things like primary and secondary adrenal insufficiency, and addison's disease. ...Read more
Adrenal gland: yesGet a more detailed answer ›
Poor correlation: Hi. Oral cortisol (aka hydrocortisone) does not reliably affect ACTH secretion nor aldosterone levels. That is somewhat unfortunate for those of us treated adrenal insufficiency, since determination of proper dose is based solely on clinical response, and not labs. Aldosterone is driven by the renin-angiotensin system bypassing the pituitary. UIHC is excellent, so you have great docs close at hand ...Read more
Why does acetylcholine, an inhibitory neurotransmitter, cause the adrenal glands to release stimulatory hormones?
Not correct: Hi. Acetyl choline (ACh) is not an inhibitory neurotransmitter. The sympathetic nervous system uses ACh as the neurotransmitter in the sympathetic ganglia (the 1st synapse outside the CNS). Usually that's from one neuron to another, but in the adrenal medulla, the cells are really the second neuron, but they release their contents (catecholamines) into the blood, not onto an organ (like the heart) ...Read moreSee 1 more doctor answer
What pituitary hormones cause the adrenal gland to produce mineralocorticoids, glucocorticoids, and androgens and estrogens including pregnenolone?
Pituitary & steroids: Hi. Pituitary ACTH regulates adrenal cortisol production; it also acutely stimulates aldosterone, but is not the principle regulator. LH principally stimulates gonadal steroid hormone production (both genders make androgens & estrogens, but in opposite dominance). Pregnenolone is early in the steroidogenic pathway in both adrenals and gonads. Good luck! ...Read more
43 yo f, afternoon cortisol high, cortisol suppression test high, CT of adrenal glands normal. Other causes of elevated cortisol?
Enlarged pituitary, no adenoma. Neurological endocrine system disregulation incl. fluctuating thyroid hormone w/goiter (when high). High urine pH 9.0.
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Yes: Glandulars have been a traditional source of these hormones, but there absorption is not realiable. Check with your doctor or check out acam which is an organization that has investigated and held standards on hormone supplementation. They even have a physician referral on there website. ...Read moreSee 1 more doctor answer
ACTH ALDO Cortisol: I have seen two families in which ACTH is the major driver for aldo production. They have the syndrome called GRA (Glucocorticoid Remedial Aldosteronism) caused by a cross over mutation in the genes controlling aldo production so that the major controller of aldo is ACTH. As you are young and making this question if you also have HTN your team should consider this. Many do not have low K. ...Read moreSee 1 more doctor answer
No: However, alcohol can cause various symptoms that can seem like the adrenal glands are releasing adrenalin. Some people will flush after drinking alcohol, this can occur for genetic reasons (common in asians) or rarely due to a medical disorder (carcinoid, lymphoma). ...Read moreSee 1 more doctor answer
Hormones: A tropic hormone is a hormone secreted by one gland and then stimulates another gland; for example, the pituitary makes TSH, which targets the thyroid and causes the thyroid to make T4 and T3 (liothyronine). The thyroid hormones (T4, T3 (liothyronine)) target other organs (heart, CNS, GI, etc), but not really other glands, so are not really tropic hormones. ...Read more
Depends on case: If you mean suppressing the gland, such as using bromocryptine for a pituitary adenoma, it can help control the symtpoms and prolactinomas can shrink. For other tumors, this may not be the case art all - for metastases to the pituitary or for craniopharyngioma, addressing hormone function generally does not affect the tumor's growth, although hormone symptoms can be relieved quite a bit. ...Read moreSee 1 more doctor answer
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