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Doctor insights on: Hypothalamus Adrenals Cortisol Response Myasthenia

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Could my hypothalamus be giving orders to the adrenals to produce a surge of cortisol in response to my myasthenia gravis?

Could my hypothalamus be giving orders to the adrenals to produce a surge of cortisol in response to my myasthenia gravis?

Yes: The hypothalamus will stimulate the adrenals when there is any physical, mental or emotional stress. If the myasthenia is symptomatic, that is a stress and could stimulate the hypothalamus. ...Read more

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Hypothalamus (Definition)

An area of brain that deals with maintenance of homeostasis throughout the body. Important for temperature, appetite, weight regulation, coordination with other areas ...Read more


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I have vomiting episodes that lead to systemic inflammatory response syndrome without sepsis. What causes sirs? Insufficient cortisol from adrenals?

I have vomiting episodes that lead to systemic inflammatory response syndrome without sepsis.  What causes sirs?  Insufficient cortisol from adrenals?

Multifactorial: As a general rule, inflammatory conditions which produce the criteria necessary to term a condition sirs are induced by cytokine release, but there are many other possibilities. Generally not adrenal insufficiency. You seem to be trying to acquire a shorthand medical education. It is not that simple. ...Read more

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I found out that I have low fasting cortisol 111 nmol/l , does that mean all my adrenal hormones are low?

I found out that I have low fasting cortisol 111 nmol/l , does that mean all my adrenal hormones are low?

WHile your: Result is low, one abnormal test doesn't make a diagnosis. It needs to be repeated with an 8am blood cortisol at a quality lab and correlated with historical and physical exam data (plus potentially other lab tests) by your physician. Besides, the other adrenal hormones are controlled by different mechanisms than cortisol. ...Read more

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How is cortisol related to an adrenal imbalance?

How is cortisol related to an adrenal imbalance?

Too Much/Too Little: While the adrenal gland makes several hormones, too little or too much cortisol is usually the problem for adrenals that are under- or overactive. Adrenal insufficiency, or failure, causes weight loss, muscle weakness, low blood pressure, and can be fatal. In cushing's syndrome (too much cortisol) weight gain, the face may be round, and there is increased risk for diabetes and high bp. ...Read more

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Hi, (Adrenal question) Can you have a normal ACTH test and still have low cortisol or adrenal.issues?

Hi,

(Adrenal question)

Can you have a normal ACTH test and still have low cortisol or adrenal.issues?

Yes: A spot ACTH test is not especially helpful in the workup of possible adrenal disease. It's all about stimulation and suppression testing. ...Read more

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Cortisol, a.M. Test 15.7. No p.M. Test. Concerned re adrenal glands: 20+ cort. Inj. In 2011. Should I have the a.M. And p.M. Tests?

No: Your values are normal (both am cortisol and acth stimulation test). No concern about adrenal insufficiency at this time. The pm test is good to rule out cushing's syndrome, which is not a problem for you either. ...Read more

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Can high pm cortisol point to a problem with adrenal glands?

Can high pm cortisol point to a problem with adrenal glands?

Not at all: since the hormone is being put out. Could in theory could be a growth from the adrenal gland putting out extra hormones. We'd have to see the values the lab normally gets to know if this is even abnormal. ...Read more

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How do multiple steroid shots effect cortisol level and adrenal functioning?

Cortisol shots: Cortisol shots will increase your blood cortisol level and look after your adrenal glands. Please go online and look for "cortisol shots" - you will learn a lot. Take your time reading the several articles. ...Read more