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Hypopituitarism Dwarfism Orphan
What are symptoms of hypopituitarism and when to be concerned? Hx of dwarfism caused by deficient pituitary.
Hypopituitarism: If entire pituitary affected, not just growth hormone, other hormones such as gonadotropins, TSH and ACTH will be low as well. Symptoms are those of target gland dysfunction - absent or diminished secondary sex characteristics or menses, thyroid or adrenal insufficiency. ...Read more
Hypopituitarism is a medical condition in which the pituitary gland, located in the brain, does not function. The pituitary gland is responsible for making many important hormones that tell other glands in the body to produce hormones such as thyroid hormone, growth hormone, estrogen, and testosterone. Children with hypopituitarism have inadequate levels of one or ...Read more
It could be a cause: Causes of hypopituitarism can directly affect the pituitary gland or indirectly through the hypothalamus, which in turn affects the pituitary gland. Causes of hypopituitarism, of which there are many, includes sarcoidosis - a rare inflammation of the lymph nodes and other tissues throughout the body. ...Read more
Dwarfism: There are multiple types of dwarfism: achondroplasia, diastrophic dysplasia, spondylo-epiphyseal dysplasia (SED), pseudoachondroplasia, hypochondroplasia, & osterogenesis imperfecta. Dwarfish is "An adult, height of 4 ft. 10 in. or under, as the result of a medical or genetic condition." per LPA. ...Read more
Enormously: the knowledge of the osteochondrodystrophies causing dwarfism has now reached the molecular level. Some are much better elucidated than others. In some, preventive therapy has become available. You may check of each entity, perhaps starting with Online Mendelian Inheritance in Man--OMIM.org ...Read more
Prenatal ultrasound.: Screening with prenatal ultrasound is one way to screen for certain types of dwarfism that could potentially be lethal. Prenatal screening and diagnosis are primarily performed in the second trimester, but late first trimester fetal structural assessment is becoming more common with advances in transvaginal ultrasound imaging and the widespread use of first trimester screening for down syndrome. ...Read more
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