Doctor insights on:
Hypereosinophilic Syndrome In Children
Too many eosinophils: Eosinophils, a type of immune cell, are too abundant in hes. High eos can be seen in allergies and in some parasitic or viral infections. If these conditions are ruled out, you are left with hes. High eos can lead to inflammation in the skin, internal organs, nerves, and the lining of blood vessels and the heart. See a hematologist or immunologist for more information. ...Read more
Multiple tests: A complete blood count will determine if you have increased numbers of eosinophils. Then, common causes of high eosinophils must be excluded, usually by blood tests for parasites or other infections. Other blood tests and/or imaging tests can determine if the eosinophils are damaging internal organs. Finally, blood tests and bone marrow biopsy can help determine what is causing the condition. ...Read more
Here: Characterized by an eosinophil count > 1500 on repeat testing over 6 months, with involvement of the heart or other organs. Ruling out secondary causes of eosinophilia (infections, malignancy, etc). Ruling out a clonal bone marrow disorder. There are now essentially 6 different subtypes of he's (hypereosinophilic syndrome). If undefined, it is referred to as idiopathic. Hope this helps. ...Read more
Very variable: It depends on what organs are involved. Fatigue, increased blood coagulation, enlarged liver, strokes can occur, problems with nerves such as numbness, there can be recurrent swelling, shortness of breath, wheezing, and nonspecific rashes. Blood work and biopsies may needed to make the diagnosis as most symptoms are not specific to the condition. ...Read more
Hypereosinophilic syndrome is a rare disorder. See this site for more info.
http://www. Ncbi. Nlm. Nih. Gov/pmc/articles/PMC2045078/ ...Read more
High eos and exclude: HES is when there is elevated eosinophil count (≥ 1500 eosinophils/mm³) in the blood for at least 6 months without any recognizable cause, with involvement of either the heart, nervous system, or bone marrow. HES affects many organs at the same time, symptoms may include rash, hives, dizziness, cough, short of breath, confusion, memory loss, fever, fatigue and mouth sores. ...Read more
Typically prednisone: Prednisone or other corticosteroids are very effective at controlling eosinophil levels and are usually the first line of treatment. Do to the long-term side effects, other medications like Hydroxyurea and interferon-alpha can be used to lower the doses of steroids that are required. If the syndrome is related to a leukemia or a specific dna mutation, treatment with chemotherapy may be effective. ...Read more
For an assessment:
Of the child's developmental needs & toilet-training readiness, if < 3 yrs. Old, call Pam Barton,
Franklin County Help Me Grow Coordinator at (614) 227-9860. If 3-5 yrs. Old, call Lynn Brannon, Director of Early Childhood Special Education at (614) 542-4106.
At the same time, call (614) 355-8080 for an evaluation at the Down Syndrome Clinic, Nationwide Children's Hospital, (614) 355-8080. ...Read more
Many issues: This is a descriptive term indicating an infant or child who fails to meet the parameters for age and size and weight and in fact is falling down. This is an index of problems that need explanation. Categories: child abuse, malabsorption, severe infection, chronic illness, cancer, blood dyscrasias, inherited issues. Your pediatrician should be consulted immediately to sort this out. ...Read more
DS Phenotype: Flattened face, upward-slanting eyes, skin folds at inner corners of eyes, transverse palmar crease, & more. Many have congenital anomalies of the heart, intestine, skeletal system & other organs, along with hearing loss, vision problems & certain blood & neurological disorders. Intellectual Disability is usually mild-moderate. Guidelines for medical & developmental care are well-established. ...Read more
Yes.: :simply discuss this issue with your ob/gyn specialists to allay your concerns! ...Read more
No: As a phenomenologically defined entity, and considering that no reliable universal genetic marker was identified, it is impossible to predict with any level of certainty as of now. What is possible though is the diagnostic evaluation of a kid already exhibiting behaviors. ...Read more
ACOG charts show the: Risk of having a fetus with a Trisomy 21, Down Syndrome, at prenatal diagnosis vs. The risk of having a live-born infant with DS because ~ 25% are lost. If there is no family history or prior infant with DS, at age 42 at delivery, the risk is 1/63; risk at 16 weeks' gestation is 1/50 - 1/55. Risk of any chromosomal disorder at term is 1/42. If 43 at term, DS risk is 1/49; of any trisomy, 1/33. ...Read more
No good data: This is not quite rare, but also not common. It is more often reported in children but can occur at any age. It is not a mental illness, but a physical perceptual distortion and is usually not part of a dangerous condition. It may be associated w/ migraines or tle and a neurologist might help. Try not to worry about 'craziness' - it is not that. Wish I could offer #s, but I can't. ...Read more
Very rare: This syndrome, where objects or the person's own body appear larger or smaller than normal, is very rare. Some sources say only about 300 adults & children in the us have this. Another source said 9% of teens had transient experiences of micropsia. It can be a migraine equivalent, & can also appear in conditions like seizures, CNS infections, brain tumors, drug use, macular degeneration, etc. ...Read more
Infertility: It may be primary or secondary infertiliy ...Read more
Tachybrady syndrome: TachyBrady Syndrome can occur in young children albeit rare. Infants may present with poor feeding or easy fatigability, which may also be evident in toddlers and older children. Laboratory studies include electrolytes, thyroid studies, echocardiogram, holter monitoring in older children, EP studies. Patients with symptoms require pacemakers and avoidance of medications that can exacerbate the prob. ...Read more
Doubt it would Hapn: While females with ds are capable of reproduction (with difficult pregnancies) males with few exceptions are not. For a male to be capable, I would expect him to be a partially affected mosaic ds & fertility would depend on the tissues of his body that has ds info. Having family support thru their lives is a great asset to anyone with ds or any impairment. ...Read more
I need statistics on aspergers syndrome. How many people have it (children, young adults, adults).?
Not Well Established: The prevalence of Asperger syndrome (as) is not well established. Experts estimate that as many as 1 in 88 children age 8 will have an autism spectrum disorder. No studies have yet been conducted to determine the incidence of Asperger syndrome in adult populations, but studies of children with the disorder suggest that their problems with socialization and communication continue into adulthood. ...Read more
I am 28 and have foetal alcohol syndrome, I was just wondering if it could be inherited by my 3 children?
FAS: Fetal alcohol syndrome is a label applied to infants where alcohol exposure during pregnancy created toxic effects on otherwise normal tissues. The features range from altered facial appearance & heart defects to injury to brain cells. Add or learning problems is common. This is not genetic & no mom passes it to her kids unless she ingests alcohol during pregnancy & replicates the injuries. ...Read more
Hello. I was wondering how likely it is for a male Schmidt's syndrome patient to pass on the disease to his children. Thank you.
Risk is there: The genetic risk is there but it doesn't mean all of them will get it. It just means they have a higher chance than the general population to develop the disease. The best thing is to go see the endocrinologist or the geneticist to determine their individual risks. There are test that can be done to determine if they have the antibody and the HLA type ...Read more
See an expert!:
Most children with asperger's present a group of specific signs: having repetitive and unusual behaviors; having ritualistic behaviors and pre-occupations (obsessions) with certain topics; difficulties "reading" social cues and difficulties empathizing (sensitivity to other's feelings); in general, difficulties relating to others.
Please, seek a specialist to diagnose this condition properly! ...Read more